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Doppler Audio Signal Analysis as an Additional Tool in Evaluation of Umbilical Artery Circulation.

Thuring, Ann LU ; Källén, Karin LU ; Brännström, Jonas LU ; Jansson, Tomas LU and Marsal, Karel LU (2015) In Ultraschall in der Medizin (Stuttgart, Germany : 1980)
Abstract
Purpose: To investigate the predictive capacity of a new method for sound spectrum analysis of Doppler signals recorded from the umbilical artery in high-risk pregnancies. Material and Methods: The retrospective study comprised 127 pregnant women with various pregnancy complications between 23 and 39 gestational weeks. Umbilical artery blood flow velocity waveforms were recorded with Doppler ultrasound and characterized by pulsatility index (PI) and blood flow class (BFC). Doppler audio signals were stored on a digital video recorder and the sound frequency at the energy level 15 dB below its peak (MAXpeak-15 dB) was estimated off-line. The prediction of probability for composite adverse pregnancy outcome (operative delivery for fetal... (More)
Purpose: To investigate the predictive capacity of a new method for sound spectrum analysis of Doppler signals recorded from the umbilical artery in high-risk pregnancies. Material and Methods: The retrospective study comprised 127 pregnant women with various pregnancy complications between 23 and 39 gestational weeks. Umbilical artery blood flow velocity waveforms were recorded with Doppler ultrasound and characterized by pulsatility index (PI) and blood flow class (BFC). Doppler audio signals were stored on a digital video recorder and the sound frequency at the energy level 15 dB below its peak (MAXpeak-15 dB) was estimated off-line. The prediction of probability for composite adverse pregnancy outcome (operative delivery for fetal distress, admission to neonatal intensive care unit, perinatal death) was evaluated using the area under the curve (AUC) of the receiver operating characteristics (ROC) curve. Results: With increasing umbilical artery BFC, the MAXpeak-15 dB frequencies decreased (p < 0.0001) and the PI increased (p < 0.0001). The ROC AUCs for adverse outcome for MAXpeak-15 dB and for PI were 0.842 and 0.836 (p = 0.88), respectively. For the combination of MAXpeak-15 dB and PI, the corresponding AUC was 0.894, significantly higher than that of PI (p < 0.03) and of MAXpeak-15 dB (p < 0.05). Conclusion: Umbilical artery Doppler sound spectrum analysis might be a useful supplement to PI in the clinical evaluation of fetoplacental circulation. (Less)
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author
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Contribution to journal
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published
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in
Ultraschall in der Medizin (Stuttgart, Germany : 1980)
external identifiers
  • PMID:26422669
ISSN
1438-8782
DOI
10.1055/s-0035-1553302
language
English
LU publication?
yes
id
a94a8fe3-1f2c-4e60-9ec3-1be9621e70c8 (old id 8159931)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26422669?dopt=Abstract
date added to LUP
2015-11-02 11:20:49
date last changed
2016-09-20 03:30:56
@misc{a94a8fe3-1f2c-4e60-9ec3-1be9621e70c8,
  abstract     = {Purpose: To investigate the predictive capacity of a new method for sound spectrum analysis of Doppler signals recorded from the umbilical artery in high-risk pregnancies. Material and Methods: The retrospective study comprised 127 pregnant women with various pregnancy complications between 23 and 39 gestational weeks. Umbilical artery blood flow velocity waveforms were recorded with Doppler ultrasound and characterized by pulsatility index (PI) and blood flow class (BFC). Doppler audio signals were stored on a digital video recorder and the sound frequency at the energy level 15 dB below its peak (MAXpeak-15 dB) was estimated off-line. The prediction of probability for composite adverse pregnancy outcome (operative delivery for fetal distress, admission to neonatal intensive care unit, perinatal death) was evaluated using the area under the curve (AUC) of the receiver operating characteristics (ROC) curve. Results: With increasing umbilical artery BFC, the MAXpeak-15 dB frequencies decreased (p &lt; 0.0001) and the PI increased (p &lt; 0.0001). The ROC AUCs for adverse outcome for MAXpeak-15 dB and for PI were 0.842 and 0.836 (p = 0.88), respectively. For the combination of MAXpeak-15 dB and PI, the corresponding AUC was 0.894, significantly higher than that of PI (p &lt; 0.03) and of MAXpeak-15 dB (p &lt; 0.05). Conclusion: Umbilical artery Doppler sound spectrum analysis might be a useful supplement to PI in the clinical evaluation of fetoplacental circulation.},
  author       = {Thuring, Ann and Källén, Karin and Brännström, Jonas and Jansson, Tomas and Marsal, Karel},
  issn         = {1438-8782},
  language     = {eng},
  month        = {09},
  series       = {Ultraschall in der Medizin (Stuttgart, Germany : 1980)},
  title        = {Doppler Audio Signal Analysis as an Additional Tool in Evaluation of Umbilical Artery Circulation.},
  url          = {http://dx.doi.org/10.1055/s-0035-1553302},
  year         = {2015},
}