Purkinje Neurons During Eye Blink Conditioning and New Mechanisms of Cerebellar Learning and Timing
(2021) p.1335-1344- Abstract
During eyeblink conditioning, Purkinje cells that control blinking develop an inhibitory response to the conditional stimulus. This conditional response (CR) in the Purkinje cell shows a number of striking similarities to the overt blink CR, including adaptive timing. The evidence suggests that the Purkinje cell CR drives the overt CR. Recent results show that the Purkinje cell CR does not depend on long-term depression but on a novel mechanism that enables the cell to learn the temporal interval between conditional and unconditional stimuli and time of the CR accordingly.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/0cf3d9ea-4ebc-44bf-86c6-0634fafa7acd
- author
- Hesslow, Germund LU ; Jirenhed, Dan Anders LU and Johansson, Fredrik LU
- organization
- publishing date
- 2021
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- Cerebellum, Classical conditioning, Purkinje cells, Simple spikes, Timing
- host publication
- Handbook of the Cerebellum and Cerebellar Disorders : Second Edition: Volume 3 - Second Edition: Volume 3
- pages
- 10 pages
- publisher
- Springer International Publishing
- external identifiers
-
- scopus:85153661403
- ISBN
- 9783030238100
- 9783030238094
- DOI
- 10.1007/978-3-030-23810-0_115
- language
- English
- LU publication?
- yes
- id
- 0cf3d9ea-4ebc-44bf-86c6-0634fafa7acd
- date added to LUP
- 2023-07-21 15:04:03
- date last changed
- 2024-08-10 09:54:10
@inbook{0cf3d9ea-4ebc-44bf-86c6-0634fafa7acd, abstract = {{<p>During eyeblink conditioning, Purkinje cells that control blinking develop an inhibitory response to the conditional stimulus. This conditional response (CR) in the Purkinje cell shows a number of striking similarities to the overt blink CR, including adaptive timing. The evidence suggests that the Purkinje cell CR drives the overt CR. Recent results show that the Purkinje cell CR does not depend on long-term depression but on a novel mechanism that enables the cell to learn the temporal interval between conditional and unconditional stimuli and time of the CR accordingly.</p>}}, author = {{Hesslow, Germund and Jirenhed, Dan Anders and Johansson, Fredrik}}, booktitle = {{Handbook of the Cerebellum and Cerebellar Disorders : Second Edition: Volume 3}}, isbn = {{9783030238100}}, keywords = {{Cerebellum; Classical conditioning; Purkinje cells; Simple spikes; Timing}}, language = {{eng}}, pages = {{1335--1344}}, publisher = {{Springer International Publishing}}, title = {{Purkinje Neurons During Eye Blink Conditioning and New Mechanisms of Cerebellar Learning and Timing}}, url = {{http://dx.doi.org/10.1007/978-3-030-23810-0_115}}, doi = {{10.1007/978-3-030-23810-0_115}}, year = {{2021}}, }