Inhibition of ConA-induced proliferative response in human lymphocytes by podophyllotoxin and a detergent, Tween80
(1988) In Clinical and Experimental Rheumatology 6(4). p.405-407- Abstract
- Podophyllotoxin (CPH86), at concentrations of 5 ng/ml or more, inhibited [3H]-thymidine uptake of ConA-induced proliferation of human peripheral mononuclear blood cells. Tween80, the detergent included in the anti-inflammatory drug Proresid, containing podophyllum lignan derivatives, also inhibited lymphocyte proliferation in a dose-dependent manner. Combination of the two drugs did not, or did only weakly, potentiate the inhibitory effect of each drug.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1104258
- author
- Månsson, Bengt LU ; Geborek, Pierre LU ; Hallberg, T and Sturfelt, Gunnar LU
- organization
- publishing date
- 1988
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Clinical and Experimental Rheumatology
- volume
- 6
- issue
- 4
- pages
- 405 - 407
- publisher
- Pacini
- external identifiers
-
- pmid:3229031
- ISSN
- 1593-098X
- language
- English
- LU publication?
- yes
- id
- 1e9713ca-a79d-4e09-bd4f-dc1734300b14 (old id 1104258)
- date added to LUP
- 2016-04-01 12:21:44
- date last changed
- 2018-11-21 20:06:39
@article{1e9713ca-a79d-4e09-bd4f-dc1734300b14, abstract = {{Podophyllotoxin (CPH86), at concentrations of 5 ng/ml or more, inhibited [3H]-thymidine uptake of ConA-induced proliferation of human peripheral mononuclear blood cells. Tween80, the detergent included in the anti-inflammatory drug Proresid, containing podophyllum lignan derivatives, also inhibited lymphocyte proliferation in a dose-dependent manner. Combination of the two drugs did not, or did only weakly, potentiate the inhibitory effect of each drug.}}, author = {{Månsson, Bengt and Geborek, Pierre and Hallberg, T and Sturfelt, Gunnar}}, issn = {{1593-098X}}, language = {{eng}}, number = {{4}}, pages = {{405--407}}, publisher = {{Pacini}}, series = {{Clinical and Experimental Rheumatology}}, title = {{Inhibition of ConA-induced proliferative response in human lymphocytes by podophyllotoxin and a detergent, Tween80}}, volume = {{6}}, year = {{1988}}, }