Increasing prevalence of adenocarcinoma of the oesophagus and gastro-oesophageal junction: A study of the Swedish population between 1970 and 1997
(2001) In European Journal of Surgery 167(10). p.748-757- Abstract
- Objective: To see whether there was an increasing incidence of adenocarcinoma of the oesophagus and gastric cardia in the Swedish population. If there is a rising trend and variations in it can be found, could it be explained as a period or cohort phenomenon:? The data were also compared with the incidence of squamous cell carcinoma and gastric cancer with the gastric cardia excluded. Design: Retrospective study. Setting: Sweden. Subjects: Swedish population. Main Outcome measures: Age standardised incidence for each sex was calculated using the age distribution of the world population as a reference. Age-period-cohort models were fitted to data using Poisson regression to model log incidence rates. Results: For the combined group of... (More)
- Objective: To see whether there was an increasing incidence of adenocarcinoma of the oesophagus and gastric cardia in the Swedish population. If there is a rising trend and variations in it can be found, could it be explained as a period or cohort phenomenon:? The data were also compared with the incidence of squamous cell carcinoma and gastric cancer with the gastric cardia excluded. Design: Retrospective study. Setting: Sweden. Subjects: Swedish population. Main Outcome measures: Age standardised incidence for each sex was calculated using the age distribution of the world population as a reference. Age-period-cohort models were fitted to data using Poisson regression to model log incidence rates. Results: For the combined group of adenocarcinoma in the oesophagus and gastric cardia age standardised incidence gradually increased during the study period. The median increase between adjacent five-year intervals was 20% in women and 14% in men. A period effect was evident in men. Conclusion: This study shows that the incidence of adenocarcinoma of the oesophagus and gastroesophageal junction is rising for both men and women in the Swedish population. This is explained as a period effect. As well as previously-described risk factors such as gastro-oesophageal reflux, obesity, and smoking, the increasing incidence can be explained as a shift in classification from squamous cell carcinoma to adenocarcinoma after 1985. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1118555
- author
- Walther, Charles ; Zilling, Thomas ; Perfekt, Roland LU and Möller, Torgil LU
- organization
- publishing date
- 2001
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- adenocarcinoma, squamous cell carcinoma, Barrett's oesophagus, oesophagus, gastroesophageal junction, incidence
- in
- European Journal of Surgery
- volume
- 167
- issue
- 10
- pages
- 748 - 757
- publisher
- Oxford University Press
- external identifiers
-
- wos:000172759100005
- scopus:0035662714
- pmid:11775726
- ISSN
- 1102-4151
- DOI
- 10.1080/11024150152707725
- language
- English
- LU publication?
- yes
- id
- f698ead5-765b-43d9-9533-c74b9c4f11ef (old id 1118555)
- date added to LUP
- 2016-04-01 17:08:18
- date last changed
- 2022-01-29 00:39:11
@article{f698ead5-765b-43d9-9533-c74b9c4f11ef,
abstract = {{Objective: To see whether there was an increasing incidence of adenocarcinoma of the oesophagus and gastric cardia in the Swedish population. If there is a rising trend and variations in it can be found, could it be explained as a period or cohort phenomenon:? The data were also compared with the incidence of squamous cell carcinoma and gastric cancer with the gastric cardia excluded. Design: Retrospective study. Setting: Sweden. Subjects: Swedish population. Main Outcome measures: Age standardised incidence for each sex was calculated using the age distribution of the world population as a reference. Age-period-cohort models were fitted to data using Poisson regression to model log incidence rates. Results: For the combined group of adenocarcinoma in the oesophagus and gastric cardia age standardised incidence gradually increased during the study period. The median increase between adjacent five-year intervals was 20% in women and 14% in men. A period effect was evident in men. Conclusion: This study shows that the incidence of adenocarcinoma of the oesophagus and gastroesophageal junction is rising for both men and women in the Swedish population. This is explained as a period effect. As well as previously-described risk factors such as gastro-oesophageal reflux, obesity, and smoking, the increasing incidence can be explained as a shift in classification from squamous cell carcinoma to adenocarcinoma after 1985.}},
author = {{Walther, Charles and Zilling, Thomas and Perfekt, Roland and Möller, Torgil}},
issn = {{1102-4151}},
keywords = {{adenocarcinoma; squamous cell carcinoma; Barrett's oesophagus; oesophagus; gastroesophageal junction; incidence}},
language = {{eng}},
number = {{10}},
pages = {{748--757}},
publisher = {{Oxford University Press}},
series = {{European Journal of Surgery}},
title = {{Increasing prevalence of adenocarcinoma of the oesophagus and gastro-oesophageal junction: A study of the Swedish population between 1970 and 1997}},
url = {{http://dx.doi.org/10.1080/11024150152707725}},
doi = {{10.1080/11024150152707725}},
volume = {{167}},
year = {{2001}},
}