Gelation By Design
(2026)- Abstract
- In order to meet the demands of consumers, personal care products, like any other product, must undergo constant innovation in order to stay up to date with consumer needs, preferences whilst conforming to commercial regulation. Here, the works contained within this thesis firstly aim to gain greater understanding of current actives in aluminium antiperspirant products, through the manufacture and use of a custom built in situ SAXS microfluidic device, which is discussed in Paper i. This study aimed to observe the gel formation and therefore eccrine sweat gland plugging capabilities of aluminium antiperspirants within a model environment.
Secondly, we studied type V eutectic solvent mixtures as potential novel carriers for personal... (More) - In order to meet the demands of consumers, personal care products, like any other product, must undergo constant innovation in order to stay up to date with consumer needs, preferences whilst conforming to commercial regulation. Here, the works contained within this thesis firstly aim to gain greater understanding of current actives in aluminium antiperspirant products, through the manufacture and use of a custom built in situ SAXS microfluidic device, which is discussed in Paper i. This study aimed to observe the gel formation and therefore eccrine sweat gland plugging capabilities of aluminium antiperspirants within a model environment.
Secondly, we studied type V eutectic solvent mixtures as potential novel carriers for personal care products, but with a focus on the fundamental interactions occurring within the systems rather than an application based approach. These solvents are novel, composing of mixtures of non-ionic hydrogen bond donors and hydrogen bond acceptors. Their simple preparation, without the need for elaborate synthesis or expensive chemicals, makes them accessible to chemists both in the research lab and potentially industrially. They are normally are composed of naturally sourced, environmentally benign compounds such as fatty acids and terpenes, which causes them to be hydrophobic and considered much more ’green’ comparedto petrochemically derived oils, which they are suggested as suitable candidates to replace. A (deep) eutectic solvent was used initially as the dispersed (droplet) phase in an emulsion system in Paper ii. In this study, the addition of stearate salts to the droplet phase formulations were found to affect the surfactant packing of non-ionic poloxamer surfactants at the emulsion interface, improving the emulsion stability.
Finally, in Paper iii, the tunable nature of 25 ES mixtures were explored by comparing
the gelation properties of the low molecular weight gelator, 12-hydroxystearic acid, within them. This work compared how the pairings of compounds in the ES mixtures interacted via hydrogen bonding with themselves and in turn the HSA, to form a range of eutectogels, illustrating the tunable nature of these novel solvents. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1267e6ad-16ae-4f4e-af33-bd78309c87a2
- author
- Green, Bradley LU
- supervisor
-
- Karen Edler LU
- opponent
-
- Prof. Cabral, Joao, Imperial College London, The United Kingdom.
- organization
- publishing date
- 2026-08-19
- type
- Thesis
- publication status
- published
- subject
- pages
- 165 pages
- publisher
- Centre for Analysis and Synthesis, Department of Chemistry, Lund University
- defense location
- Lecture Hall KC:A, Kemicentrum, Naturvetarvägen 22, Faculty of Engineering LTH, Lund University, Lund.
- defense date
- 2026-09-14 09:00:00
- ISBN
- 978-91-90202-88-3
- 978-91-90202-87-6
- language
- English
- LU publication?
- yes
- id
- 1267e6ad-16ae-4f4e-af33-bd78309c87a2
- date added to LUP
- 2026-08-13 13:27:00
- date last changed
- 2026-08-20 09:38:14
@phdthesis{1267e6ad-16ae-4f4e-af33-bd78309c87a2,
abstract = {{In order to meet the demands of consumers, personal care products, like any other product, must undergo constant innovation in order to stay up to date with consumer needs, preferences whilst conforming to commercial regulation. Here, the works contained within this thesis firstly aim to gain greater understanding of current actives in aluminium antiperspirant products, through the manufacture and use of a custom built in situ SAXS microfluidic device, which is discussed in Paper i. This study aimed to observe the gel formation and therefore eccrine sweat gland plugging capabilities of aluminium antiperspirants within a model environment.<br/>Secondly, we studied type V eutectic solvent mixtures as potential novel carriers for personal care products, but with a focus on the fundamental interactions occurring within the systems rather than an application based approach. These solvents are novel, composing of mixtures of non-ionic hydrogen bond donors and hydrogen bond acceptors. Their simple preparation, without the need for elaborate synthesis or expensive chemicals, makes them accessible to chemists both in the research lab and potentially industrially. They are normally are composed of naturally sourced, environmentally benign compounds such as fatty acids and terpenes, which causes them to be hydrophobic and considered much more ’green’ comparedto petrochemically derived oils, which they are suggested as suitable candidates to replace. A (deep) eutectic solvent was used initially as the dispersed (droplet) phase in an emulsion system in Paper ii. In this study, the addition of stearate salts to the droplet phase formulations were found to affect the surfactant packing of non-ionic poloxamer surfactants at the emulsion interface, improving the emulsion stability.<br/>Finally, in Paper iii, the tunable nature of 25 ES mixtures were explored by comparing<br/>the gelation properties of the low molecular weight gelator, 12-hydroxystearic acid, within them. This work compared how the pairings of compounds in the ES mixtures interacted via hydrogen bonding with themselves and in turn the HSA, to form a range of eutectogels, illustrating the tunable nature of these novel solvents.}},
author = {{Green, Bradley}},
isbn = {{978-91-90202-88-3}},
language = {{eng}},
month = {{08}},
publisher = {{Centre for Analysis and Synthesis, Department of Chemistry, Lund University}},
school = {{Lund University}},
title = {{Gelation By Design}},
url = {{https://lup.lub.lu.se/search/files/257950473/Bradley_George_Green_-_WEBB-4.pdf}},
year = {{2026}},
}