Improved sensibility of the foot after temporary cutaneous anesthesia of the lower leg.
(2009) In NeuroReport 20. p.37-41- Abstract
- Cutaneous anesthesia (EMLA_cream) of the forearm results in rapid improvement of hand sensibility, and here we applied this concept in the lower extremity. This double-blind study with 40 volunteers randomized to cutaneous application of anesthetic cream to the lower leg showed a significant improvement 2 h after treatment in touch thresholds in the EMLA group as compared with the placebo group. In 12 volunteers, fMRI examination was performed before and after treatment. Improvement was not associated with a visible cortical expansion of the cortical foot area. This novel finding may have considerable therapeutic potential in the treatment of foot sensibility disturbances in various neuropathies, such as diabetic neuropathy.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1271112
- author
- Rosén, Birgitta LU ; Björkman, Anders LU ; Weibull, Andreas LU ; Svensson, Jonas LU and Lundborg, Göran LU
- organization
- publishing date
- 2009
- type
- Contribution to journal
- publication status
- published
- subject
- in
- NeuroReport
- volume
- 20
- pages
- 37 - 41
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- wos:000262208800008
- pmid:19033877
- scopus:58149236787
- ISSN
- 1473-558X
- DOI
- 10.1097/WNR.0b013e32831b4486
- language
- English
- LU publication?
- yes
- id
- 422f0230-cc64-451e-a6e1-1bada4ffd2d9 (old id 1271112)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/19033877?dopt=Abstract
- date added to LUP
- 2016-04-04 08:33:50
- date last changed
- 2022-01-29 03:37:35
@article{422f0230-cc64-451e-a6e1-1bada4ffd2d9,
abstract = {{Cutaneous anesthesia (EMLA_cream) of the forearm results in rapid improvement of hand sensibility, and here we applied this concept in the lower extremity. This double-blind study with 40 volunteers randomized to cutaneous application of anesthetic cream to the lower leg showed a significant improvement 2 h after treatment in touch thresholds in the EMLA group as compared with the placebo group. In 12 volunteers, fMRI examination was performed before and after treatment. Improvement was not associated with a visible cortical expansion of the cortical foot area. This novel finding may have considerable therapeutic potential in the treatment of foot sensibility disturbances in various neuropathies, such as diabetic neuropathy.}},
author = {{Rosén, Birgitta and Björkman, Anders and Weibull, Andreas and Svensson, Jonas and Lundborg, Göran}},
issn = {{1473-558X}},
language = {{eng}},
pages = {{37--41}},
publisher = {{Lippincott Williams & Wilkins}},
series = {{NeuroReport}},
title = {{Improved sensibility of the foot after temporary cutaneous anesthesia of the lower leg.}},
url = {{http://dx.doi.org/10.1097/WNR.0b013e32831b4486}},
doi = {{10.1097/WNR.0b013e32831b4486}},
volume = {{20}},
year = {{2009}},
}