SPECT findings in children with specific language impairment.
(2005) In Cortex 41(3). p.316-326- Abstract
- Findings from 99mTc-HMPAO SPECT measurements at rest in a group of 19 school-age children with specific language
impairment (SLI) were compared to a group of 12 children with attention-deficit hyperactivity disorder (ADHD). The
regional cerebral blood flow (CBF) distributions were different in the two groups. Children with SLI showed significantly lower CBF values in the right parietal region and in the subcortical region compared to the ADHD group. In addition, the SLI group had symmetric CBF distributions in the left and right temporal regions, whereas the ADHD group showed the usual asymmetry with left-sided hemispheric predominance in the temporal regions. The findings give further evidence for anomalous... (More) - Findings from 99mTc-HMPAO SPECT measurements at rest in a group of 19 school-age children with specific language
impairment (SLI) were compared to a group of 12 children with attention-deficit hyperactivity disorder (ADHD). The
regional cerebral blood flow (CBF) distributions were different in the two groups. Children with SLI showed significantly lower CBF values in the right parietal region and in the subcortical region compared to the ADHD group. In addition, the SLI group had symmetric CBF distributions in the left and right temporal regions, whereas the ADHD group showed the usual asymmetry with left-sided hemispheric predominance in the temporal regions. The findings give further evidence for anomalous neurodevelopment with deviant hemispheric lateralization as an important factor in the aetiology of SLI. They also point to the role of subcortical structures in language impairment in childhood. Earlier focus on cortical structures in SLI research needs to be widened to include subcortical regions as well. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/138190
- author
- Ors, Marianne LU ; Ryding, Erik LU ; Lindgren, Magnus LU ; Gustafsson, Peik LU ; Blennow, Gösta LU and Rosén, Ingmar LU
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- lateralization, ADHD, specific language impairment, thalamus, language disorders, SPECT, basal ganglia
- in
- Cortex
- volume
- 41
- issue
- 3
- pages
- 316 - 326
- publisher
- Elsevier
- external identifiers
-
- wos:000228941100005
- pmid:15871597
- scopus:17644363685
- ISSN
- 1973-8102
- language
- English
- LU publication?
- yes
- id
- ef4c0a0d-c304-4200-8d52-66e76146919e (old id 138190)
- alternative location
- http://www.cortex-online.org/ftp/ftpDownloader.asp?action=downloadFile&dirID=158&fileID=812
- date added to LUP
- 2016-04-04 08:33:09
- date last changed
- 2022-03-15 08:18:59
@article{ef4c0a0d-c304-4200-8d52-66e76146919e,
abstract = {{Findings from 99mTc-HMPAO SPECT measurements at rest in a group of 19 school-age children with specific language<br/><br>
impairment (SLI) were compared to a group of 12 children with attention-deficit hyperactivity disorder (ADHD). The<br/><br>
regional cerebral blood flow (CBF) distributions were different in the two groups. Children with SLI showed significantly lower CBF values in the right parietal region and in the subcortical region compared to the ADHD group. In addition, the SLI group had symmetric CBF distributions in the left and right temporal regions, whereas the ADHD group showed the usual asymmetry with left-sided hemispheric predominance in the temporal regions. The findings give further evidence for anomalous neurodevelopment with deviant hemispheric lateralization as an important factor in the aetiology of SLI. They also point to the role of subcortical structures in language impairment in childhood. Earlier focus on cortical structures in SLI research needs to be widened to include subcortical regions as well.}},
author = {{Ors, Marianne and Ryding, Erik and Lindgren, Magnus and Gustafsson, Peik and Blennow, Gösta and Rosén, Ingmar}},
issn = {{1973-8102}},
keywords = {{lateralization; ADHD; specific language impairment; thalamus; language disorders; SPECT; basal ganglia}},
language = {{eng}},
number = {{3}},
pages = {{316--326}},
publisher = {{Elsevier}},
series = {{Cortex}},
title = {{SPECT findings in children with specific language impairment.}},
url = {{http://www.cortex-online.org/ftp/ftpDownloader.asp?action=downloadFile&dirID=158&fileID=812}},
volume = {{41}},
year = {{2005}},
}