Multinodal high throughput acoustic trapping of exosomes from urine samples
(2019) 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 p.2-3- Abstract
We report a new design of an acoustophoretic trapping device with greatly increased capacity and throughput, compared to current commercial systems. Acoustic trapping enables nanoparticle and exosome enrichment without the need for ultracentrifugation. The commercial acoustic trapping technology, AcouTrap (AcouSort AB), typically operates at flow rates < 50 μl/min which limits processing of larger samples. Using a larger capillary that supports an acoustic multi-node resonance, capacity and throughput was increased a factor 40 compared to AcouTrap. It was possible to capture and enrich exosomes from urine samples at 30 times higher flow rate than previously reported.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/23b79b6f-0fe6-4e5e-92cd-304ceb6b2941
- author
- Broman, Axel LU ; Lenshof, Andreas LU ; Evander, Mikael LU ; Ku, Anson LU ; Ceder, Yvonne LU and Laurell, Thomas LU
- organization
- publishing date
- 2019
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- Acoustic trapping, Acoustophoresis, Exosomes, High throughput
- host publication
- 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
- series title
- 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
- pages
- 2 pages
- publisher
- Chemical and Biological Microsystems Society
- conference name
- 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
- conference location
- Basel, Switzerland
- conference dates
- 2019-10-27 - 2019-10-31
- external identifiers
-
- scopus:85094943795
- ISBN
- 9781733419000
- language
- English
- LU publication?
- yes
- id
- 23b79b6f-0fe6-4e5e-92cd-304ceb6b2941
- date added to LUP
- 2020-11-24 07:57:14
- date last changed
- 2023-10-22 20:48:38
@inproceedings{23b79b6f-0fe6-4e5e-92cd-304ceb6b2941, abstract = {{<p>We report a new design of an acoustophoretic trapping device with greatly increased capacity and throughput, compared to current commercial systems. Acoustic trapping enables nanoparticle and exosome enrichment without the need for ultracentrifugation. The commercial acoustic trapping technology, AcouTrap (AcouSort AB), typically operates at flow rates < 50 μl/min which limits processing of larger samples. Using a larger capillary that supports an acoustic multi-node resonance, capacity and throughput was increased a factor 40 compared to AcouTrap. It was possible to capture and enrich exosomes from urine samples at 30 times higher flow rate than previously reported.</p>}}, author = {{Broman, Axel and Lenshof, Andreas and Evander, Mikael and Ku, Anson and Ceder, Yvonne and Laurell, Thomas}}, booktitle = {{23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019}}, isbn = {{9781733419000}}, keywords = {{Acoustic trapping; Acoustophoresis; Exosomes; High throughput}}, language = {{eng}}, pages = {{2--3}}, publisher = {{Chemical and Biological Microsystems Society}}, series = {{23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019}}, title = {{Multinodal high throughput acoustic trapping of exosomes from urine samples}}, year = {{2019}}, }