X-ray structure analysis of free-standing lipid membranes facilitated by micromachined apertures
(2008) In Langmuir 24(9). p.4952-4958- Abstract
Silicon and Teflon substrates have been structured by wet etching and a focused ion beam (FIB) to obtain very defined, clean apertures. Planar, free-standing lipid membranes (black lipid membranes (BLM)) with enhanced long-term stability have been prepared on these apertures by the methods of Montal and Müller1.2 as well as Müller and Rudin. 3 The stability and geometric control enables the use of X-ray analysis of free-standing single bilayers. With the presented setup, simultaneous structural and electrophysiological measurements will become feasible.
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https://lup.lub.lu.se/record/25aa24ee-d6ca-4cba-a11f-b8a6e7329ebd
- author
- Beerlink, André ; Wilbrandt, P. J. ; Ziegler, E. ; Carbone, D. LU ; Metzger, T. H. and Salditt, Tim
- publishing date
- 2008-05-06
- type
- Contribution to journal
- publication status
- published
- in
- Langmuir
- volume
- 24
- issue
- 9
- pages
- 7 pages
- publisher
- The American Chemical Society (ACS)
- external identifiers
-
- scopus:44249127772
- pmid:18370435
- ISSN
- 0743-7463
- DOI
- 10.1021/la703704x
- language
- English
- LU publication?
- no
- id
- 25aa24ee-d6ca-4cba-a11f-b8a6e7329ebd
- date added to LUP
- 2021-12-15 11:54:46
- date last changed
- 2024-05-04 19:38:30
@article{25aa24ee-d6ca-4cba-a11f-b8a6e7329ebd, abstract = {{<p>Silicon and Teflon substrates have been structured by wet etching and a focused ion beam (FIB) to obtain very defined, clean apertures. Planar, free-standing lipid membranes (black lipid membranes (BLM)) with enhanced long-term stability have been prepared on these apertures by the methods of Montal and Müller<sup>1.2</sup> as well as Müller and Rudin. <sup>3</sup> The stability and geometric control enables the use of X-ray analysis of free-standing single bilayers. With the presented setup, simultaneous structural and electrophysiological measurements will become feasible.</p>}}, author = {{Beerlink, André and Wilbrandt, P. J. and Ziegler, E. and Carbone, D. and Metzger, T. H. and Salditt, Tim}}, issn = {{0743-7463}}, language = {{eng}}, month = {{05}}, number = {{9}}, pages = {{4952--4958}}, publisher = {{The American Chemical Society (ACS)}}, series = {{Langmuir}}, title = {{X-ray structure analysis of free-standing lipid membranes facilitated by micromachined apertures}}, url = {{http://dx.doi.org/10.1021/la703704x}}, doi = {{10.1021/la703704x}}, volume = {{24}}, year = {{2008}}, }