Bulk Acoustic Wave Activated Droplet Generation and Isolation
(2023) 48th National Conference on Fluid Mechanics and Fluid Power, FMFP 2021 In Lecture Notes in Mechanical Engineering p.145-150- Abstract
On-demand droplet generation from a continuously flowing stream of aqueous phase has profound applications in dropletbased microfluidics for rare event encapsulation studies. Here, we present acoustic relocation-based droplet generation from co-flowing immiscible fluids in an on-demand manner using bulk acoustic wave (BAW). After on-demand droplet generation, droplets are isolated using the same acoustic force resulted from BAW. Two different acoustic relocation regimes are observed, namely, stream to droplet relocation and stream to stream relocation regime. Our experimental observation reveals that to generate droplets from co-flowing fluids, the following conditions must be satisfied. First, the co-flowing immiscible stream should be... (More)
On-demand droplet generation from a continuously flowing stream of aqueous phase has profound applications in dropletbased microfluidics for rare event encapsulation studies. Here, we present acoustic relocation-based droplet generation from co-flowing immiscible fluids in an on-demand manner using bulk acoustic wave (BAW). After on-demand droplet generation, droplets are isolated using the same acoustic force resulted from BAW. Two different acoustic relocation regimes are observed, namely, stream to droplet relocation and stream to stream relocation regime. Our experimental observation reveals that to generate droplets from co-flowing fluids, the following conditions must be satisfied. First, the co-flowing immiscible stream should be maintained in acoustic relocation conditions (Cac > 1); Second, the capillary instability should be triggered during the relocation process, which happens at capillary numbers of the co-flowing fluids should be less than 0.2 (CaL and CaH < 0.2). Finally, using BAW microfluidic chip, droplets containing microparticle were produced ondemand from co-flowing streams wherein the microparticles are added in one of the phases.
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- author
- Hemachandran, E. ; Laurell, T. LU and Sen, A. K.
- organization
-
- LU Profile Area: Light and Materials
- LTH Profile Area: Nanoscience and Semiconductor Technology
- LTH Profile Area: Engineering Health
- LUCC: Lund University Cancer Centre
- Acoustofluidics group (research group)
- SEBRA Sepsis and Bacterial Resistance Alliance (research group)
- NanoLund: Centre for Nanoscience
- MultiPark: Multidisciplinary research focused on ParkinsonĀ“s disease
- publishing date
- 2023
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- Acoustic relocation, Bulk acoustic wave, Capillary instability, Co-flow, Encapsulation, On-demand droplet
- host publication
- Fluid Mechanics and Fluid Power (Vol. 3)- Select Proceedings of FMFP 2021
- series title
- Lecture Notes in Mechanical Engineering
- editor
- Bhattacharyya, Suvanjan ; Verma, Saket and Harikrishnan, A.R.
- pages
- 6 pages
- publisher
- Springer Science and Business Media B.V.
- conference name
- 48th National Conference on Fluid Mechanics and Fluid Power, FMFP 2021
- conference location
- Pilani, India
- conference dates
- 2021-12-27 - 2021-12-29
- external identifiers
-
- scopus:85161508186
- ISSN
- 2195-4356
- 2195-4364
- ISBN
- 9789811962691
- DOI
- 10.1007/978-981-19-6270-7_26
- language
- English
- LU publication?
- yes
- id
- 25e79170-a5b0-4ca7-bb33-735d276ea2a8
- date added to LUP
- 2023-08-23 12:29:50
- date last changed
- 2024-09-07 14:34:05
@inproceedings{25e79170-a5b0-4ca7-bb33-735d276ea2a8, abstract = {{<p>On-demand droplet generation from a continuously flowing stream of aqueous phase has profound applications in dropletbased microfluidics for rare event encapsulation studies. Here, we present acoustic relocation-based droplet generation from co-flowing immiscible fluids in an on-demand manner using bulk acoustic wave (BAW). After on-demand droplet generation, droplets are isolated using the same acoustic force resulted from BAW. Two different acoustic relocation regimes are observed, namely, stream to droplet relocation and stream to stream relocation regime. Our experimental observation reveals that to generate droplets from co-flowing fluids, the following conditions must be satisfied. First, the co-flowing immiscible stream should be maintained in acoustic relocation conditions (C<sub>ac</sub> &gt; 1); Second, the capillary instability should be triggered during the relocation process, which happens at capillary numbers of the co-flowing fluids should be less than 0.2 (Ca<sub>L</sub> and Ca<sub>H</sub> &lt; 0.2). Finally, using BAW microfluidic chip, droplets containing microparticle were produced ondemand from co-flowing streams wherein the microparticles are added in one of the phases.</p>}}, author = {{Hemachandran, E. and Laurell, T. and Sen, A. K.}}, booktitle = {{Fluid Mechanics and Fluid Power (Vol. 3)- Select Proceedings of FMFP 2021}}, editor = {{Bhattacharyya, Suvanjan and Verma, Saket and Harikrishnan, A.R.}}, isbn = {{9789811962691}}, issn = {{2195-4356}}, keywords = {{Acoustic relocation; Bulk acoustic wave; Capillary instability; Co-flow; Encapsulation; On-demand droplet}}, language = {{eng}}, pages = {{145--150}}, publisher = {{Springer Science and Business Media B.V.}}, series = {{Lecture Notes in Mechanical Engineering}}, title = {{Bulk Acoustic Wave Activated Droplet Generation and Isolation}}, url = {{http://dx.doi.org/10.1007/978-981-19-6270-7_26}}, doi = {{10.1007/978-981-19-6270-7_26}}, year = {{2023}}, }