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Decreasing Blood Pressure Over Time is the Strongest Predictor of Depressive Symptoms in Octogenarian Men.

Siennicki-Lantz, Arkadiusz LU orcid ; André-Petersson, Lena LU and Elmståhl, Sölve LU (2013) In The American Journal of Geriatric Psychiatry
Abstract
OBJECTIVE: The aim of this study was to examine the longitudinal impact of blood pressure variations and vascular risk factors on depressive symptoms in the elderly. DESIGN: Longitudinal and cross-sectional cohort study. SETTING: Urban population of elderly men, city of Malmö, Sweden. PARTICIPANTS: A total of 809 randomly included men took part in a prospective cohort study, "Men born in 1914", and 171 survivors reached the age of 81 years. MEASUREMENTS: Depressive symptoms were estimated at the age of 81 using the Zung Self-Rating Depression Scale (ZSDS). Vascular risk factors were identified at both 68 and 81 years of age. RESULTS: At the age of 68, diagnosis of hypertension and on-going antihypertensive therapy were more frequent in... (More)
OBJECTIVE: The aim of this study was to examine the longitudinal impact of blood pressure variations and vascular risk factors on depressive symptoms in the elderly. DESIGN: Longitudinal and cross-sectional cohort study. SETTING: Urban population of elderly men, city of Malmö, Sweden. PARTICIPANTS: A total of 809 randomly included men took part in a prospective cohort study, "Men born in 1914", and 171 survivors reached the age of 81 years. MEASUREMENTS: Depressive symptoms were estimated at the age of 81 using the Zung Self-Rating Depression Scale (ZSDS). Vascular risk factors were identified at both 68 and 81 years of age. RESULTS: At the age of 68, diagnosis of hypertension and on-going antihypertensive therapy were more frequent in subjects with high than low ZSDS scores. In contrast, at age 81, the highest ZSDS scores correlated with low systolic blood pressure (SBP). Declining SBP between the ages of 68 and 81 was more frequent in high-scoring than in low-scoring groups. Subjects with high ZSDS scores took more drugs and had more clinical diagnoses at age 81. Those taking hypnotics and sedatives had higher ZSDS scores, lower SBP at 81, and showed more frequent decrease in SBP during the observation period. CONCLUSION: Depressive symptoms in octogenarian men could be predicted by hypertension earlier in life, and were strongly associated with decreasing SBP during the last decade. (Less)
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author
; and
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publishing date
type
Contribution to journal
publication status
published
subject
in
The American Journal of Geriatric Psychiatry
issue
Jan.,2013
publisher
Elsevier
external identifiers
  • pmid:23567417
  • wos:000330361900007
  • scopus:84884573343
  • pmid:23567417
ISSN
1545-7214
DOI
10.1016/j.jagp.2012.11.007
language
English
LU publication?
yes
id
b81c36b6-dc22-465b-93e6-b5041d27c7c2 (old id 3734015)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/23567417?dopt=Abstract
date added to LUP
2016-04-04 07:54:00
date last changed
2023-01-05 07:42:28
@article{b81c36b6-dc22-465b-93e6-b5041d27c7c2,
  abstract     = {{OBJECTIVE: The aim of this study was to examine the longitudinal impact of blood pressure variations and vascular risk factors on depressive symptoms in the elderly. DESIGN: Longitudinal and cross-sectional cohort study. SETTING: Urban population of elderly men, city of Malmö, Sweden. PARTICIPANTS: A total of 809 randomly included men took part in a prospective cohort study, "Men born in 1914", and 171 survivors reached the age of 81 years. MEASUREMENTS: Depressive symptoms were estimated at the age of 81 using the Zung Self-Rating Depression Scale (ZSDS). Vascular risk factors were identified at both 68 and 81 years of age. RESULTS: At the age of 68, diagnosis of hypertension and on-going antihypertensive therapy were more frequent in subjects with high than low ZSDS scores. In contrast, at age 81, the highest ZSDS scores correlated with low systolic blood pressure (SBP). Declining SBP between the ages of 68 and 81 was more frequent in high-scoring than in low-scoring groups. Subjects with high ZSDS scores took more drugs and had more clinical diagnoses at age 81. Those taking hypnotics and sedatives had higher ZSDS scores, lower SBP at 81, and showed more frequent decrease in SBP during the observation period. CONCLUSION: Depressive symptoms in octogenarian men could be predicted by hypertension earlier in life, and were strongly associated with decreasing SBP during the last decade.}},
  author       = {{Siennicki-Lantz, Arkadiusz and André-Petersson, Lena and Elmståhl, Sölve}},
  issn         = {{1545-7214}},
  language     = {{eng}},
  number       = {{Jan.,2013}},
  publisher    = {{Elsevier}},
  series       = {{The American Journal of Geriatric Psychiatry}},
  title        = {{Decreasing Blood Pressure Over Time is the Strongest Predictor of Depressive Symptoms in Octogenarian Men.}},
  url          = {{http://dx.doi.org/10.1016/j.jagp.2012.11.007}},
  doi          = {{10.1016/j.jagp.2012.11.007}},
  year         = {{2013}},
}