Effect of feeding colostrum versus exogenous immunoglobulin G on gastrointestinal structure and enteric nervous system in newborn pigs
(2012) In Journal of Animal Science 90. p.327-329- Abstract
- Colostrum is an indispensable source of antibodies (IgG) protecting the newborn pig against infection. We studied the effect of feeding colostrum and purified IgG on early structure and development of the gastrointestinal tract (GIT). Newborn littermate pigs were fed either colostrum, an elemental diet (ED), or an ED supplemented with purified serum IgG (ED + IgG) for 24 h or then only ED up to 72 h. Afterwards, pigs were slaughtered. Colostrum-fed pigs or ED supplemented with IgG (ED + IgG) increased thickness (P < 0.001) of stomach mucosa and muscularis (P < 0.05) compared to the ED group not receiving IgG. Feeding an ED supplemented with IgG improved morphology of the GIT towards that of colostrum-fed piglets and indicates a... (More)
- Colostrum is an indispensable source of antibodies (IgG) protecting the newborn pig against infection. We studied the effect of feeding colostrum and purified IgG on early structure and development of the gastrointestinal tract (GIT). Newborn littermate pigs were fed either colostrum, an elemental diet (ED), or an ED supplemented with purified serum IgG (ED + IgG) for 24 h or then only ED up to 72 h. Afterwards, pigs were slaughtered. Colostrum-fed pigs or ED supplemented with IgG (ED + IgG) increased thickness (P < 0.001) of stomach mucosa and muscularis (P < 0.05) compared to the ED group not receiving IgG. Feeding an ED supplemented with IgG improved morphology of the GIT towards that of colostrum-fed piglets and indicates a beneficial effect of IgG on GIT development in neonatal pigs. Immunohistochemical studies indicate that ED feeding may influence the expression of nitric oxide synthase in jejunal myenteric (but not submucous) neurons of newborn pigs. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3931381
- author
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- immunoglobulin G, elementary diet, colostrum, gut development
- in
- Journal of Animal Science
- volume
- 90
- pages
- 327 - 329
- publisher
- Oxford University Press
- external identifiers
-
- wos:000319673100105
- scopus:84882634075
- ISSN
- 1525-3163
- DOI
- 10.2527/jas.53926
- language
- English
- LU publication?
- yes
- id
- 6243351c-c074-499e-ba7a-5dedf4c4b1f5 (old id 3931381)
- date added to LUP
- 2016-04-01 10:52:52
- date last changed
- 2022-01-26 03:23:29
@article{6243351c-c074-499e-ba7a-5dedf4c4b1f5, abstract = {{Colostrum is an indispensable source of antibodies (IgG) protecting the newborn pig against infection. We studied the effect of feeding colostrum and purified IgG on early structure and development of the gastrointestinal tract (GIT). Newborn littermate pigs were fed either colostrum, an elemental diet (ED), or an ED supplemented with purified serum IgG (ED + IgG) for 24 h or then only ED up to 72 h. Afterwards, pigs were slaughtered. Colostrum-fed pigs or ED supplemented with IgG (ED + IgG) increased thickness (P < 0.001) of stomach mucosa and muscularis (P < 0.05) compared to the ED group not receiving IgG. Feeding an ED supplemented with IgG improved morphology of the GIT towards that of colostrum-fed piglets and indicates a beneficial effect of IgG on GIT development in neonatal pigs. Immunohistochemical studies indicate that ED feeding may influence the expression of nitric oxide synthase in jejunal myenteric (but not submucous) neurons of newborn pigs.}}, author = {{Wolinski, J. and Slupecka, M. and Weström, Björn and Prykhodko, O. and Ochniewicz, P. and Arciszewski, M. and Ekblad, E. and Szwiec, K. and Ushakova, X and Skibo, G. and Kovalenko, T. and Osadchenko, I. and Goncharova, K. and Botermans, J. and Pierzynowski, Stefan}}, issn = {{1525-3163}}, keywords = {{immunoglobulin G; elementary diet; colostrum; gut development}}, language = {{eng}}, pages = {{327--329}}, publisher = {{Oxford University Press}}, series = {{Journal of Animal Science}}, title = {{Effect of feeding colostrum versus exogenous immunoglobulin G on gastrointestinal structure and enteric nervous system in newborn pigs}}, url = {{http://dx.doi.org/10.2527/jas.53926}}, doi = {{10.2527/jas.53926}}, volume = {{90}}, year = {{2012}}, }