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Developments in Biobanking Workflow Standardization Providing Samples Integrity and Stability

Malm, Johan LU ; Fehniger, Thomas LU ; Danmyr, Pia LU ; Végvári, Ákos LU ; Welinder, Charlotte LU ; Lindberg, Henrik LU ; Appelqvist, Roger LU ; Sjödin, Karin LU ; Wieslander, Elisabet LU and Laurell, Thomas LU , et al. (2013) In Journal of Proteomics 95. p.38-45
Abstract
Recommendations and outlines for standardization in biobanking processes are presented by a research team with long-term experiences in clinical studies. These processes have important bearing on the use of samples in developing assays. These measurements are useful to document states of health and disease that are beneficial for academic research, commercial healthcare, drug development industry and government regulating agencies. There is a need for increasing awareness within proteomics and genomics communities regarding the basic concepts of collecting, storing and utilizing clinical samples. Quality control and samples suitability for analysis needs to be documented and validated to ensure data integrity and establish contexts for... (More)
Recommendations and outlines for standardization in biobanking processes are presented by a research team with long-term experiences in clinical studies. These processes have important bearing on the use of samples in developing assays. These measurements are useful to document states of health and disease that are beneficial for academic research, commercial healthcare, drug development industry and government regulating agencies. There is a need for increasing awareness within proteomics and genomics communities regarding the basic concepts of collecting, storing and utilizing clinical samples. Quality control and samples suitability for analysis needs to be documented and validated to ensure data integrity and establish contexts for interpretation of results. Standardized methods in proteomics and genomics are required to be practiced throughout the community allowing datasets to be comparable and shared for analysis. For example, sample processing of thousands of clinical samples, performed in 384 high-density sample tube systems in a fully automated workflow, preserves sample content, is presented showing validation criteria. Large studies will be accompanied by biological, molecular information with corresponding clinical records from patients and healthy donors. These developments position biobanks of human patient samples as an increasingly recognized major asset in disease research, future drug development and within patient care. (Less)
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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Biobank, Proteins, Antibodies, Mass spectrometry, Diseases, Standardization
in
Journal of Proteomics
volume
95
pages
38 - 45
publisher
Elsevier
external identifiers
  • wos:000332495700004
  • scopus:84888305959
  • pmid:23856607
ISSN
1874-3919
DOI
10.1016/j.jprot.2013.06.035
language
English
LU publication?
yes
id
6b8c4861-890c-462d-b224-bdda89274bd4 (old id 3970506)
date added to LUP
2016-04-01 10:42:32
date last changed
2023-08-31 09:30:10
@article{6b8c4861-890c-462d-b224-bdda89274bd4,
  abstract     = {{Recommendations and outlines for standardization in biobanking processes are presented by a research team with long-term experiences in clinical studies. These processes have important bearing on the use of samples in developing assays. These measurements are useful to document states of health and disease that are beneficial for academic research, commercial healthcare, drug development industry and government regulating agencies. There is a need for increasing awareness within proteomics and genomics communities regarding the basic concepts of collecting, storing and utilizing clinical samples. Quality control and samples suitability for analysis needs to be documented and validated to ensure data integrity and establish contexts for interpretation of results. Standardized methods in proteomics and genomics are required to be practiced throughout the community allowing datasets to be comparable and shared for analysis. For example, sample processing of thousands of clinical samples, performed in 384 high-density sample tube systems in a fully automated workflow, preserves sample content, is presented showing validation criteria. Large studies will be accompanied by biological, molecular information with corresponding clinical records from patients and healthy donors. These developments position biobanks of human patient samples as an increasingly recognized major asset in disease research, future drug development and within patient care.}},
  author       = {{Malm, Johan and Fehniger, Thomas and Danmyr, Pia and Végvári, Ákos and Welinder, Charlotte and Lindberg, Henrik and Appelqvist, Roger and Sjödin, Karin and Wieslander, Elisabet and Laurell, Thomas and Hober, Sophia and Berven, Frode and Fenyö, David and Wang, Xiangdong and Andrén, Per E and Edula, Goutham and Carlsohn, Elisabet and Fuentes, Manuel and Nilsson, Carol and Dahlbäck, Magnus and Rezeli, Melinda and Erlinge, David and Marko-Varga, György}},
  issn         = {{1874-3919}},
  keywords     = {{Biobank; Proteins; Antibodies; Mass spectrometry; Diseases; Standardization}},
  language     = {{eng}},
  pages        = {{38--45}},
  publisher    = {{Elsevier}},
  series       = {{Journal of Proteomics}},
  title        = {{Developments in Biobanking Workflow Standardization Providing Samples Integrity and Stability}},
  url          = {{http://dx.doi.org/10.1016/j.jprot.2013.06.035}},
  doi          = {{10.1016/j.jprot.2013.06.035}},
  volume       = {{95}},
  year         = {{2013}},
}