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Rabbit bone matrix induces bone formation in the athymic rat

Aspenberg, Per LU ; Thorngren, Karl Göran LU and Lohmander, Stefan LU orcid (1988) In Acta Orthopaedica 59(3). p.276-278
Abstract

Rabbit and rat bone matrix were implanted in athymic rat muscle, and the bone yield was measured as total calcium content after 4, 6, and 8 weeks. Matrix from both species induced equal amounts of new bone in the athymic rat. In rabbit and normal rat, the xenogenic matrix induced little or no bone formation. Thus, in the case of rabbit and rat, bone induction is species specific due to immunogenic mechanisms. the athymic rat can be used to measure inductive properties of bone matrix from different species.

Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Orthopaedica
volume
59
issue
3
pages
3 pages
publisher
Taylor & Francis
external identifiers
  • scopus:0023898031
  • pmid:3381658
ISSN
1745-3674
DOI
10.3109/17453678809149362
language
English
LU publication?
yes
id
3ceb9827-e590-41d3-a5ec-294005ab1c87
date added to LUP
2016-05-04 13:03:11
date last changed
2024-01-04 02:43:04
@article{3ceb9827-e590-41d3-a5ec-294005ab1c87,
  abstract     = {{<p>Rabbit and rat bone matrix were implanted in athymic rat muscle, and the bone yield was measured as total calcium content after 4, 6, and 8 weeks. Matrix from both species induced equal amounts of new bone in the athymic rat. In rabbit and normal rat, the xenogenic matrix induced little or no bone formation. Thus, in the case of rabbit and rat, bone induction is species specific due to immunogenic mechanisms. the athymic rat can be used to measure inductive properties of bone matrix from different species.</p>}},
  author       = {{Aspenberg, Per and Thorngren, Karl Göran and Lohmander, Stefan}},
  issn         = {{1745-3674}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{276--278}},
  publisher    = {{Taylor & Francis}},
  series       = {{Acta Orthopaedica}},
  title        = {{Rabbit bone matrix induces bone formation in the athymic rat}},
  url          = {{http://dx.doi.org/10.3109/17453678809149362}},
  doi          = {{10.3109/17453678809149362}},
  volume       = {{59}},
  year         = {{1988}},
}