Randomised controlled trial of lifestyle interventions for abdominal obesity in primary health care
(2024) In Primary Health Care Research and Development 25.- Abstract
Aim: Assess effects on waist circumference from diet with or without cereal grains and with or without long-term physical exercise. Background: Elevated waist circumference is an indicator of increased abdominal fat storage and is accordingly associated with increased cardiovascular mortality. This is likely due to the association between lifestyle-induced changes in waist circumference and cardiovascular risk factors. Reductions in waist circumference may be facilitated by diet without cereal grains combined with long-term physical exercise. Methods: Two-year randomised controlled trial with factorial trial design in individuals at increased risk of cardiovascular disease with increased waist circumference. Participants were allocated... (More)
Aim: Assess effects on waist circumference from diet with or without cereal grains and with or without long-term physical exercise. Background: Elevated waist circumference is an indicator of increased abdominal fat storage and is accordingly associated with increased cardiovascular mortality. This is likely due to the association between lifestyle-induced changes in waist circumference and cardiovascular risk factors. Reductions in waist circumference may be facilitated by diet without cereal grains combined with long-term physical exercise. Methods: Two-year randomised controlled trial with factorial trial design in individuals at increased risk of cardiovascular disease with increased waist circumference. Participants were allocated diet based on current Swedish dietary guidelines with or without cereal grains (baseline diet information supported by monthly group sessions) and with or without physical exercise (pedometers and two initial months of weekly structured exercise followed by written prescription of physical activity) or control group. The primary outcome was the change in waist circumference. Findings: The greatest mean intervention group difference in the change in waist circumference among the 73 participants (47 women and 26 men aged 23-79 years) was at one year between participants allocated a diet without cereal grains and no exercise and participants allocated a diet with cereal grains and no exercise [M = -5.3 cm and -0.9 cm, respectively; mean difference = 4.4 cm, 4.0%, 95% CI (0.0%, 8.0%), P = 0.051, Cohen's d = 0.75]. All group comparisons in the change in waist circumference were non-significant despite the greatest group difference being more than double that estimated in the pre-study power calculation. The non-significance was likely caused by too few participants and a greater than expected variability in the change in waist circumference. The greatest mean intervention group difference strengthens the possibility that dietary exclusion of cereal grains could be related to greater reduction in waist circumference.
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- author
- Carrera-Bastos, Pedro LU ; Rydhög, Björn LU ; Fontes-Villalba, Maelán LU ; Arvidsson, Daniel ; Granfeldt, Yvonne LU ; Sundquist, Kristina LU and Jönsson, Tommy LU
- organization
- publishing date
- 2024-04
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- cardiovascular disease, cereal grains, disease prevention, obesity, physical exercise, waist circumference
- in
- Primary Health Care Research and Development
- volume
- 25
- article number
- e19
- publisher
- Cambridge University Press
- external identifiers
-
- pmid:38639002
- scopus:85190841946
- ISSN
- 1463-4236
- DOI
- 10.1017/S1463423624000069
- language
- English
- LU publication?
- yes
- id
- 3e824954-1868-4b2d-8760-d4408c3f4a6c
- date added to LUP
- 2025-01-10 14:40:29
- date last changed
- 2025-01-24 16:16:26
@article{3e824954-1868-4b2d-8760-d4408c3f4a6c,
abstract = {{<p>Aim: Assess effects on waist circumference from diet with or without cereal grains and with or without long-term physical exercise. Background: Elevated waist circumference is an indicator of increased abdominal fat storage and is accordingly associated with increased cardiovascular mortality. This is likely due to the association between lifestyle-induced changes in waist circumference and cardiovascular risk factors. Reductions in waist circumference may be facilitated by diet without cereal grains combined with long-term physical exercise. Methods: Two-year randomised controlled trial with factorial trial design in individuals at increased risk of cardiovascular disease with increased waist circumference. Participants were allocated diet based on current Swedish dietary guidelines with or without cereal grains (baseline diet information supported by monthly group sessions) and with or without physical exercise (pedometers and two initial months of weekly structured exercise followed by written prescription of physical activity) or control group. The primary outcome was the change in waist circumference. Findings: The greatest mean intervention group difference in the change in waist circumference among the 73 participants (47 women and 26 men aged 23-79 years) was at one year between participants allocated a diet without cereal grains and no exercise and participants allocated a diet with cereal grains and no exercise [M = -5.3 cm and -0.9 cm, respectively; mean difference = 4.4 cm, 4.0%, 95% CI (0.0%, 8.0%), P = 0.051, Cohen's d = 0.75]. All group comparisons in the change in waist circumference were non-significant despite the greatest group difference being more than double that estimated in the pre-study power calculation. The non-significance was likely caused by too few participants and a greater than expected variability in the change in waist circumference. The greatest mean intervention group difference strengthens the possibility that dietary exclusion of cereal grains could be related to greater reduction in waist circumference.</p>}},
author = {{Carrera-Bastos, Pedro and Rydhög, Björn and Fontes-Villalba, Maelán and Arvidsson, Daniel and Granfeldt, Yvonne and Sundquist, Kristina and Jönsson, Tommy}},
issn = {{1463-4236}},
keywords = {{cardiovascular disease; cereal grains; disease prevention; obesity; physical exercise; waist circumference}},
language = {{eng}},
publisher = {{Cambridge University Press}},
series = {{Primary Health Care Research and Development}},
title = {{Randomised controlled trial of lifestyle interventions for abdominal obesity in primary health care}},
url = {{http://dx.doi.org/10.1017/S1463423624000069}},
doi = {{10.1017/S1463423624000069}},
volume = {{25}},
year = {{2024}},
}