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Management of acute stroke in patients taking novel oral anticoagulants

Hankey, Graeme J. ; Norrving, Bo LU ; Hacke, Werner and Steiner, Thorsten (2014) In International Journal of Stroke 9(5). p.627-632
Abstract
Each year, 1 center dot 0-2 center dot 0% of individuals with atrial fibrillation and 0 center dot 1-0 center dot 2% of those with venous thromboembolism who are receiving one of the novel oral anticoagulants (dabigatran, rivaroxaban, or apixaban) can be expected to experience an acute ischemic stroke. Additionally, 0 center dot 2-0 center dot 5% of individuals with atrial fibrillation who are receiving one of the novel oral anticoagulants can be expected to experience an intracranial hemorrhage. This opinion piece addresses the current literature and offers practical approaches to the management of patients receiving novel oral anticoagulants who present with an ischemic or hemorrhagic stroke. Specifically, we discuss the role of... (More)
Each year, 1 center dot 0-2 center dot 0% of individuals with atrial fibrillation and 0 center dot 1-0 center dot 2% of those with venous thromboembolism who are receiving one of the novel oral anticoagulants (dabigatran, rivaroxaban, or apixaban) can be expected to experience an acute ischemic stroke. Additionally, 0 center dot 2-0 center dot 5% of individuals with atrial fibrillation who are receiving one of the novel oral anticoagulants can be expected to experience an intracranial hemorrhage. This opinion piece addresses the current literature and offers practical approaches to the management of patients receiving novel oral anticoagulants who present with an ischemic or hemorrhagic stroke. Specifically, we discuss the role of thrombolysis in anticoagulated patients with acute ischemic stroke and factors to consider concerning restarting anticoagulation after acute ischemic and hemorrhagic stroke. (Less)
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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
acute stroke, anticoagulants, intracerebral hemorrhage, secondary, prevention, thrombolytic therapy
in
International Journal of Stroke
volume
9
issue
5
pages
627 - 632
publisher
Wiley-Blackwell
external identifiers
  • wos:000337588200019
  • scopus:84902084942
  • pmid:24891030
ISSN
1747-4949
DOI
10.1111/ijs.12295
language
English
LU publication?
yes
id
419ffa44-aef3-4d17-b6f1-cda6bc540531 (old id 4609430)
date added to LUP
2016-04-01 11:12:39
date last changed
2022-04-20 17:50:52
@article{419ffa44-aef3-4d17-b6f1-cda6bc540531,
  abstract     = {{Each year, 1 center dot 0-2 center dot 0% of individuals with atrial fibrillation and 0 center dot 1-0 center dot 2% of those with venous thromboembolism who are receiving one of the novel oral anticoagulants (dabigatran, rivaroxaban, or apixaban) can be expected to experience an acute ischemic stroke. Additionally, 0 center dot 2-0 center dot 5% of individuals with atrial fibrillation who are receiving one of the novel oral anticoagulants can be expected to experience an intracranial hemorrhage. This opinion piece addresses the current literature and offers practical approaches to the management of patients receiving novel oral anticoagulants who present with an ischemic or hemorrhagic stroke. Specifically, we discuss the role of thrombolysis in anticoagulated patients with acute ischemic stroke and factors to consider concerning restarting anticoagulation after acute ischemic and hemorrhagic stroke.}},
  author       = {{Hankey, Graeme J. and Norrving, Bo and Hacke, Werner and Steiner, Thorsten}},
  issn         = {{1747-4949}},
  keywords     = {{acute stroke; anticoagulants; intracerebral hemorrhage; secondary; prevention; thrombolytic therapy}},
  language     = {{eng}},
  number       = {{5}},
  pages        = {{627--632}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{International Journal of Stroke}},
  title        = {{Management of acute stroke in patients taking novel oral anticoagulants}},
  url          = {{http://dx.doi.org/10.1111/ijs.12295}},
  doi          = {{10.1111/ijs.12295}},
  volume       = {{9}},
  year         = {{2014}},
}