Walking by design : how to build artificial molecular motors made of proteins
(2024) In Nano Futures 8(4).- Abstract
To design an artificial protein-based molecular motor that can autonomously step along a track is a key challenge of protein design and synthetic biology. We lay out a roadmap for how to achieve this aim, based on a modular approach that combines the use of natural, non-motor proteins with de novo design. We define what can be considered to constitute a successful artificial protein motor, identify key steps along the path to achieve these designs, and provide a vision for the future beyond this aim.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/85648734-4591-4a6e-aad7-f83277087366
- author
- Nilsson, Patrik F.
LU
; Zink, Anna
; Laprévote, Olivier M.C.
; Korosec, Chapin S.
; Gustafsson, Nils
LU
; Robertson, Neil O.
; Forde, Nancy R.
; Eichhorn, Ralf
; Höcker, Birte
; Curmi, Paul M.G.
and Linke, Heiner
LU
(Less) - organization
-
- Solid State Physics
- Physical Chemistry
- Division of Translational Cancer Research
- NanoLund: Centre for Nanoscience
- LTH Profile Area: Nanoscience and Semiconductor Technology
- LU Profile Area: Light and Materials
- Ophthalmology Imaging Research Group (research group)
- LTH Profile Area: Engineering Health
- publishing date
- 2024-12-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- molecular motors, nanotechnology, protein design, proteins, synthetic biology
- in
- Nano Futures
- volume
- 8
- issue
- 4
- article number
- 042501
- publisher
- IOP Publishing
- external identifiers
-
- scopus:85206882043
- ISSN
- 2399-1984
- DOI
- 10.1088/2399-1984/ad7d7e
- language
- English
- LU publication?
- yes
- additional info
- Publisher Copyright: © 2024 The Author(s). Published by IOP Publishing Ltd.
- id
- 85648734-4591-4a6e-aad7-f83277087366
- date added to LUP
- 2024-11-26 10:56:02
- date last changed
- 2025-04-04 14:41:02
@article{85648734-4591-4a6e-aad7-f83277087366,
abstract = {{<p>To design an artificial protein-based molecular motor that can autonomously step along a track is a key challenge of protein design and synthetic biology. We lay out a roadmap for how to achieve this aim, based on a modular approach that combines the use of natural, non-motor proteins with de novo design. We define what can be considered to constitute a successful artificial protein motor, identify key steps along the path to achieve these designs, and provide a vision for the future beyond this aim.</p>}},
author = {{Nilsson, Patrik F. and Zink, Anna and Laprévote, Olivier M.C. and Korosec, Chapin S. and Gustafsson, Nils and Robertson, Neil O. and Forde, Nancy R. and Eichhorn, Ralf and Höcker, Birte and Curmi, Paul M.G. and Linke, Heiner}},
issn = {{2399-1984}},
keywords = {{molecular motors; nanotechnology; protein design; proteins; synthetic biology}},
language = {{eng}},
month = {{12}},
number = {{4}},
publisher = {{IOP Publishing}},
series = {{Nano Futures}},
title = {{Walking by design : how to build artificial molecular motors made of proteins}},
url = {{http://dx.doi.org/10.1088/2399-1984/ad7d7e}},
doi = {{10.1088/2399-1984/ad7d7e}},
volume = {{8}},
year = {{2024}},
}