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Extracellular Matrix Remodelling In COPD

Westergren-Thorsson, Gunilla LU orcid ; Bjermer, Leif LU and Hallgren, Oskar LU (2014) In European Medical Journal p.1-6
Abstract
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease that involves major remodelling of cells and tissue in the lung. There has been much focus on the inflammatory response, while less attention has been paid to structural changes and alterations of the extracellular matrix (ECM). In this review we revisit some of the latest findings on what is currently known about ECM alterations in COPD. We also discuss mechanisms involved in tissue repair and pay extra attention to the potential role of glycosaminoglycans in the disease.
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author
; and
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publishing date
type
Contribution to journal
publication status
published
subject
in
European Medical Journal
pages
1 - 6
language
English
LU publication?
yes
id
985d1945-0f98-473c-ab32-8841baed02d6
date added to LUP
2016-12-12 14:26:30
date last changed
2021-03-22 16:33:57
@article{985d1945-0f98-473c-ab32-8841baed02d6,
  abstract     = {{Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease that involves major remodelling of cells and tissue in the lung. There has been much focus on the inflammatory response, while less attention has been paid to structural changes and alterations of the extracellular matrix (ECM). In this review we revisit some of the latest findings on what is currently known about ECM alterations in COPD. We also discuss mechanisms involved in tissue repair and pay extra attention to the potential role of glycosaminoglycans in the disease.}},
  author       = {{Westergren-Thorsson, Gunilla and Bjermer, Leif and Hallgren, Oskar}},
  language     = {{eng}},
  month        = {{11}},
  pages        = {{1--6}},
  series       = {{European Medical Journal}},
  title        = {{Extracellular Matrix Remodelling In COPD}},
  url          = {{https://lup.lub.lu.se/search/files/18129965/Hallgren_2014_COPD_remodelling.pdf}},
  year         = {{2014}},
}