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A suggestion for the quantification of precise and bounded probability to quantify epistemic uncertainty in scientific assessments

Raices Cruz, Ivette LU ; Troffaes, Matthias C.M. and Sahlin, Ullrika LU orcid (2022) In Risk Analysis 42(2). p.239-253
Abstract

An honest communication of uncertainty about quantities of interest enhances transparency in scientific assessments. To support this communication, risk assessors should choose appropriate ways to evaluate and characterize epistemic uncertainty. A full treatment of uncertainty requires methods that distinguish aleatory from epistemic uncertainty. Quantitative expressions for epistemic uncertainty are advantageous in scientific assessments because they are nonambiguous and enable individual uncertainties to be characterized and combined in a systematic way. Since 2019, the European Food Safety Authority (EFSA) recommends assessors to express epistemic uncertainty in conclusions of scientific assessments quantitatively by subjective... (More)

An honest communication of uncertainty about quantities of interest enhances transparency in scientific assessments. To support this communication, risk assessors should choose appropriate ways to evaluate and characterize epistemic uncertainty. A full treatment of uncertainty requires methods that distinguish aleatory from epistemic uncertainty. Quantitative expressions for epistemic uncertainty are advantageous in scientific assessments because they are nonambiguous and enable individual uncertainties to be characterized and combined in a systematic way. Since 2019, the European Food Safety Authority (EFSA) recommends assessors to express epistemic uncertainty in conclusions of scientific assessments quantitatively by subjective probability. A subjective probability can be used to represent an expert judgment, which may or may not be updated using Bayes's rule to integrate evidence available for the assessment and could be either precise or approximate. Approximate (or bounded) probabilities may be enough for decision making and allow experts to reach agreement on certainty when they struggle to specify precise subjective probabilities. The difference between the lower and upper bound on a subjective probability can also be used to reflect someone's strength of knowledge. In this article, we demonstrate how to quantify uncertainty by bounded probability, and explicitly distinguish between epistemic and aleatory uncertainty, by means of robust Bayesian analysis, including standard Bayesian analysis through precise probability as a special case. For illustration, the two analyses are applied to an intake assessment.

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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Risk Analysis
volume
42
issue
2
pages
239 - 253
publisher
John Wiley & Sons Inc.
external identifiers
  • pmid:35007348
  • scopus:85122651970
ISSN
0272-4332
DOI
10.1111/risa.13871
language
English
LU publication?
yes
id
9bdf9b48-c314-4385-b3a8-81f3033346af
date added to LUP
2022-02-18 14:40:39
date last changed
2024-07-02 07:19:31
@article{9bdf9b48-c314-4385-b3a8-81f3033346af,
  abstract     = {{<p>An honest communication of uncertainty about quantities of interest enhances transparency in scientific assessments. To support this communication, risk assessors should choose appropriate ways to evaluate and characterize epistemic uncertainty. A full treatment of uncertainty requires methods that distinguish aleatory from epistemic uncertainty. Quantitative expressions for epistemic uncertainty are advantageous in scientific assessments because they are nonambiguous and enable individual uncertainties to be characterized and combined in a systematic way. Since 2019, the European Food Safety Authority (EFSA) recommends assessors to express epistemic uncertainty in conclusions of scientific assessments quantitatively by subjective probability. A subjective probability can be used to represent an expert judgment, which may or may not be updated using Bayes's rule to integrate evidence available for the assessment and could be either precise or approximate. Approximate (or bounded) probabilities may be enough for decision making and allow experts to reach agreement on certainty when they struggle to specify precise subjective probabilities. The difference between the lower and upper bound on a subjective probability can also be used to reflect someone's strength of knowledge. In this article, we demonstrate how to quantify uncertainty by bounded probability, and explicitly distinguish between epistemic and aleatory uncertainty, by means of robust Bayesian analysis, including standard Bayesian analysis through precise probability as a special case. For illustration, the two analyses are applied to an intake assessment.</p>}},
  author       = {{Raices Cruz, Ivette and Troffaes, Matthias C.M. and Sahlin, Ullrika}},
  issn         = {{0272-4332}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{239--253}},
  publisher    = {{John Wiley & Sons Inc.}},
  series       = {{Risk Analysis}},
  title        = {{A suggestion for the quantification of precise and bounded probability to quantify epistemic uncertainty in scientific assessments}},
  url          = {{http://dx.doi.org/10.1111/risa.13871}},
  doi          = {{10.1111/risa.13871}},
  volume       = {{42}},
  year         = {{2022}},
}