Advancing breast tissue imaging with an ultrasound optical tomography (UOT) approach
(2024) SPIE Photonics Europe, 2024, Strasbourg, France 13010. p.1301006-1301006- Abstract
- Each year, about 30% of all newly diagnosed cancer cases in women worldwide are breast cancers [1]. One of the most common techniques for breast cancer diagnosis is mammography. However, this technique provides limited functional information regarding breast tissue morphology. In cases of suspected malignancy invasive techniques such as biopsy are implemented.
In this work an optical deep tissue imaging technique called ultrasound optical tomography (UOT) which combines laser light and ultrasound is implemented for a non-invasive lesion (tumour) characterization in breast tissue.
The experiments were performed using 794 nm laser wavelength, 6 MHz ultrasound frequency and a narrowband spectral filter material, Tm3+:LiNbO3. The... (More) - Each year, about 30% of all newly diagnosed cancer cases in women worldwide are breast cancers [1]. One of the most common techniques for breast cancer diagnosis is mammography. However, this technique provides limited functional information regarding breast tissue morphology. In cases of suspected malignancy invasive techniques such as biopsy are implemented.
In this work an optical deep tissue imaging technique called ultrasound optical tomography (UOT) which combines laser light and ultrasound is implemented for a non-invasive lesion (tumour) characterization in breast tissue.
The experiments were performed using 794 nm laser wavelength, 6 MHz ultrasound frequency and a narrowband spectral filter material, Tm3+:LiNbO3. The measurements were carried out in 5 cm thick agar phantoms using a range of tumor mimicking inclusions of 3 different sizes.
This work is the first deep tissue imaging demonstration using UOT at tissue relevant wavelengths. Current results indicate that the UOT technique can become an important and valuable tool for lesion characterization in breast tissue. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/b4cad3bf-83e4-4957-a54c-f94b92d87ac5
- author
- organization
-
- LTH Profile Area: Nanoscience and Semiconductor Technology
- LTH Profile Area: Engineering Health
- LU Profile Area: Light and Materials
- LTH Profile Area: Photon Science and Technology
- NanoLund: Centre for Nanoscience
- Atomic Physics
- Chemical Physics
- Centre for Environmental and Climate Science (CEC)
- LUCC: Lund University Cancer Centre
- EpiHealth: Epidemiology for Health
- Radiology Diagnostics, Malmö (research group)
- publishing date
- 2024
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- breast cancer, bio-medical imaging, diagnosis, ultrasound optical tomography, deep tissue imaging, acousto-optic effect, spectral-hole-burning filters, rare-earth-ion-doped crystals
- host publication
- Tissue Optics and Photonics III : PROCEEDINGS VOLUME 13010 SPIE PHOTONICS EUROPE | 7-12 APRIL 2024 - PROCEEDINGS VOLUME 13010 SPIE PHOTONICS EUROPE | 7-12 APRIL 2024
- editor
- Tuchin, Valery V. ; Blondel, Walter C.P.M. and Zalevsky, Zeev
- volume
- 13010
- pages
- 6 pages
- publisher
- SPIE
- conference name
- SPIE Photonics Europe, 2024, Strasbourg, France
- conference location
- Strasbourg, France
- conference dates
- 2024-06-18
- external identifiers
-
- scopus:85203186506
- DOI
- 10.1117/12.3023883
- language
- English
- LU publication?
- yes
- id
- b4cad3bf-83e4-4957-a54c-f94b92d87ac5
- date added to LUP
- 2024-09-13 14:38:08
- date last changed
- 2024-09-16 09:45:38
@inproceedings{b4cad3bf-83e4-4957-a54c-f94b92d87ac5, abstract = {{Each year, about 30% of all newly diagnosed cancer cases in women worldwide are breast cancers [1]. One of the most common techniques for breast cancer diagnosis is mammography. However, this technique provides limited functional information regarding breast tissue morphology. In cases of suspected malignancy invasive techniques such as biopsy are implemented.<br/>In this work an optical deep tissue imaging technique called ultrasound optical tomography (UOT) which combines laser light and ultrasound is implemented for a non-invasive lesion (tumour) characterization in breast tissue.<br/>The experiments were performed using 794 nm laser wavelength, 6 MHz ultrasound frequency and a narrowband spectral filter material, Tm3+:LiNbO3. The measurements were carried out in 5 cm thick agar phantoms using a range of tumor mimicking inclusions of 3 different sizes.<br/>This work is the first deep tissue imaging demonstration using UOT at tissue relevant wavelengths. Current results indicate that the UOT technique can become an important and valuable tool for lesion characterization in breast tissue.}}, author = {{Ruchkina, Maria and Zabiliute-Karaliune, Akvile and Bukarte, Egle and Kinos, Adam and Hill, David and Bengtsson, Alexander and Shortiss, Kevin and Reistad, Nina and Rippe, Lars and Swartling, Johannes and Zackrisson, Sophia and Bakic, Predrag and Kovacs, Laszlo and Kis, Zsolt and Szaller, Zsuzsanna and Lengyel, Krisztian and Thiel, Charles and Kröll, Stefan}}, booktitle = {{Tissue Optics and Photonics III : PROCEEDINGS VOLUME 13010 SPIE PHOTONICS EUROPE | 7-12 APRIL 2024}}, editor = {{Tuchin, Valery V. and Blondel, Walter C.P.M. and Zalevsky, Zeev}}, keywords = {{breast cancer; bio-medical imaging; diagnosis; ultrasound optical tomography; deep tissue imaging; acousto-optic effect; spectral-hole-burning filters; rare-earth-ion-doped crystals}}, language = {{eng}}, pages = {{1301006--1301006}}, publisher = {{SPIE}}, title = {{Advancing breast tissue imaging with an ultrasound optical tomography (UOT) approach}}, url = {{http://dx.doi.org/10.1117/12.3023883}}, doi = {{10.1117/12.3023883}}, volume = {{13010}}, year = {{2024}}, }