Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Cancer Risk in Collagenous Colitis

Larsson, Johanna K LU ; Dabos, Konstantinos J ; Höglund, Peter LU ; Bohr, Johan ; Münch, Andreas ; Giannakou, Andry ; Nemeth, Artur LU ; Wurm-Johansson, Gabriele LU ; Toth, Ervin LU and Plevris, John N , et al. (2019) In Journal of Clinical Medicine 8(11).
Abstract

Data on malignancy in patients with collagenous colitis (CC) is scarce. We aimed to determine the incidence of cancers in patients with CC. In a two-stages, observational study, data on cancers in patients diagnosed with CC during 2000-2015, were collected from two cohorts. The risk was calculated according to the age-standardized rate for the first cohort and according to the standardized incidence ratio for the second cohort. The first cohort comprised 738 patients (394 from Scotland and 344 from Sweden; mean age 71 ± 11 and 66 ± 13 years, respectively). The incidence rates for lung cancer (RR 3.9, p = 0.001), bladder cancer (RR 9.2, p = 0.019), and non-melanoma skin cancer (NMSC) (RR 15, p = 0.001) were increased. As the majority of... (More)

Data on malignancy in patients with collagenous colitis (CC) is scarce. We aimed to determine the incidence of cancers in patients with CC. In a two-stages, observational study, data on cancers in patients diagnosed with CC during 2000-2015, were collected from two cohorts. The risk was calculated according to the age-standardized rate for the first cohort and according to the standardized incidence ratio for the second cohort. The first cohort comprised 738 patients (394 from Scotland and 344 from Sweden; mean age 71 ± 11 and 66 ± 13 years, respectively). The incidence rates for lung cancer (RR 3.9, p = 0.001), bladder cancer (RR 9.2, p = 0.019), and non-melanoma skin cancer (NMSC) (RR 15, p = 0.001) were increased. As the majority of NMSC cases (15/16) came from Sweden, a second Swedish cohort, comprising 1141 patients (863 women, mean age 65 years, range 20-95 years) was collected. There were 93 cancer cases (besides NMSC). The risk for colon cancer was decreased (SIR 0.23, p= 0.0087). The risk for cutaneous squamous cell carcinoma was instead markedly increased (SIR 3.27, p = 0.001).

(Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; ; ; ; and , et al. (More)
; ; ; ; ; ; ; ; ; ; ; and (Less)
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Clinical Medicine
volume
8
issue
11
article number
1942
publisher
MDPI AG
external identifiers
  • pmid:31718057
  • scopus:85082327847
ISSN
2077-0383
DOI
10.3390/jcm8111942
language
English
LU publication?
yes
id
be1a61d7-adef-46c5-b3fe-d47ba836ced9
date added to LUP
2023-01-02 09:45:03
date last changed
2024-06-27 14:49:28
@article{be1a61d7-adef-46c5-b3fe-d47ba836ced9,
  abstract     = {{<p>Data on malignancy in patients with collagenous colitis (CC) is scarce. We aimed to determine the incidence of cancers in patients with CC. In a two-stages, observational study, data on cancers in patients diagnosed with CC during 2000-2015, were collected from two cohorts. The risk was calculated according to the age-standardized rate for the first cohort and according to the standardized incidence ratio for the second cohort. The first cohort comprised 738 patients (394 from Scotland and 344 from Sweden; mean age 71 ± 11 and 66 ± 13 years, respectively). The incidence rates for lung cancer (RR 3.9, p = 0.001), bladder cancer (RR 9.2, p = 0.019), and non-melanoma skin cancer (NMSC) (RR 15, p = 0.001) were increased. As the majority of NMSC cases (15/16) came from Sweden, a second Swedish cohort, comprising 1141 patients (863 women, mean age 65 years, range 20-95 years) was collected. There were 93 cancer cases (besides NMSC). The risk for colon cancer was decreased (SIR 0.23, p= 0.0087). The risk for cutaneous squamous cell carcinoma was instead markedly increased (SIR 3.27, p = 0.001).</p>}},
  author       = {{Larsson, Johanna K and Dabos, Konstantinos J and Höglund, Peter and Bohr, Johan and Münch, Andreas and Giannakou, Andry and Nemeth, Artur and Wurm-Johansson, Gabriele and Toth, Ervin and Plevris, John N and Fineron, Paul and Koulaouzidis, Anastasios and Sjöberg, Klas}},
  issn         = {{2077-0383}},
  language     = {{eng}},
  month        = {{11}},
  number       = {{11}},
  publisher    = {{MDPI AG}},
  series       = {{Journal of Clinical Medicine}},
  title        = {{Cancer Risk in Collagenous Colitis}},
  url          = {{http://dx.doi.org/10.3390/jcm8111942}},
  doi          = {{10.3390/jcm8111942}},
  volume       = {{8}},
  year         = {{2019}},
}