Endoscopic versus Laparoscopic Full-Thickness Biopsy in the Pathological Evaluation of the Enteric Nervous System
(2018) In Case Reports in Gastroenterology 12(1). p.32-40- Abstract
A full-thickness biopsy of the bowel wall is required to evaluate the enteric nervous system. A patient with aggravating gastrointestinal symptoms underwent a laparoscopic full-thickness biopsy of the ileum and, 1 year later, an endoscopic full-thickness biopsy of the sigmoid colon. Both samples showed enteric neuropathy characterized by vacuolated and enlarged neurons. The length of the myenteric plexus was greater in the endoscopic (23 mm) compared to the laparoscopic (11 mm) biopsy, with fewer tissue artefacts in the laparoscopic approach. Clinical deterioration was paralleled by enteric neuropathy with an increase in the percentage of vacuolated and enlarged enteric neurons from 24 to 35%.
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- author
- Ohlsson, Bodil LU ; Gustafsson, Rita J. LU ; Toth, Ervin LU ; Veress, Bèla LU and Thorlacius, Henrik LU
- organization
- publishing date
- 2018-01-19
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Enteric dysmotility, Enteric neuropathy, Full-thickness biopsy, Gastrointestinal symptoms
- in
- Case Reports in Gastroenterology
- volume
- 12
- issue
- 1
- pages
- 32 - 40
- publisher
- Karger
- external identifiers
-
- pmid:29515343
- scopus:85041014499
- ISSN
- 1662-0631
- DOI
- 10.1159/000486390
- language
- English
- LU publication?
- yes
- id
- c5284bb8-f41c-4822-8f8d-41645bbf4b2c
- date added to LUP
- 2018-02-06 15:55:42
- date last changed
- 2024-06-24 09:36:35
@article{c5284bb8-f41c-4822-8f8d-41645bbf4b2c, abstract = {{<p>A full-thickness biopsy of the bowel wall is required to evaluate the enteric nervous system. A patient with aggravating gastrointestinal symptoms underwent a laparoscopic full-thickness biopsy of the ileum and, 1 year later, an endoscopic full-thickness biopsy of the sigmoid colon. Both samples showed enteric neuropathy characterized by vacuolated and enlarged neurons. The length of the myenteric plexus was greater in the endoscopic (23 mm) compared to the laparoscopic (11 mm) biopsy, with fewer tissue artefacts in the laparoscopic approach. Clinical deterioration was paralleled by enteric neuropathy with an increase in the percentage of vacuolated and enlarged enteric neurons from 24 to 35%.</p>}}, author = {{Ohlsson, Bodil and Gustafsson, Rita J. and Toth, Ervin and Veress, Bèla and Thorlacius, Henrik}}, issn = {{1662-0631}}, keywords = {{Enteric dysmotility; Enteric neuropathy; Full-thickness biopsy; Gastrointestinal symptoms}}, language = {{eng}}, month = {{01}}, number = {{1}}, pages = {{32--40}}, publisher = {{Karger}}, series = {{Case Reports in Gastroenterology}}, title = {{Endoscopic versus Laparoscopic Full-Thickness Biopsy in the Pathological Evaluation of the Enteric Nervous System}}, url = {{http://dx.doi.org/10.1159/000486390}}, doi = {{10.1159/000486390}}, volume = {{12}}, year = {{2018}}, }