Limited effects of temafloxacin compared with ciprofloxacin on T- lymphocyte function
(1994) In Antimicrobial Agents and Chemotherapy 38(4). p.879-882- Abstract
Temafloxacin increased interleukin-2 production and mRNA levels and enhanced thymidine incorporation in stimulated lymphocyte cultures. Gamma interferon mRNA levels were unaffected. Temafloxacin also stimulated interleukin-2 gene induction, as revealed in a chloramphenicol acetyltransferase reporter gene system. However, temafloxacin exerted significantly weaker effects in these respects than did ciprofloxacin.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/c7bce6e1-bd22-417d-8fb7-aae74e3e224f
- author
- Riesbeck, Kristian LU and Forsgren, Arne LU
- organization
- publishing date
- 1994-01-01
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Antimicrobial Agents and Chemotherapy
- volume
- 38
- issue
- 4
- pages
- 879 - 882
- publisher
- American Society for Microbiology
- external identifiers
-
- scopus:0028265747
- pmid:8031064
- ISSN
- 0066-4804
- DOI
- 10.1128/AAC.38.4.879
- language
- English
- LU publication?
- yes
- id
- c7bce6e1-bd22-417d-8fb7-aae74e3e224f
- date added to LUP
- 2019-03-08 15:27:19
- date last changed
- 2024-01-15 15:35:46
@misc{c7bce6e1-bd22-417d-8fb7-aae74e3e224f, abstract = {{<p>Temafloxacin increased interleukin-2 production and mRNA levels and enhanced thymidine incorporation in stimulated lymphocyte cultures. Gamma interferon mRNA levels were unaffected. Temafloxacin also stimulated interleukin-2 gene induction, as revealed in a chloramphenicol acetyltransferase reporter gene system. However, temafloxacin exerted significantly weaker effects in these respects than did ciprofloxacin.</p>}}, author = {{Riesbeck, Kristian and Forsgren, Arne}}, issn = {{0066-4804}}, language = {{eng}}, month = {{01}}, number = {{4}}, pages = {{879--882}}, publisher = {{American Society for Microbiology}}, series = {{Antimicrobial Agents and Chemotherapy}}, title = {{Limited effects of temafloxacin compared with ciprofloxacin on T- lymphocyte function}}, url = {{http://dx.doi.org/10.1128/AAC.38.4.879}}, doi = {{10.1128/AAC.38.4.879}}, volume = {{38}}, year = {{1994}}, }