Structural Biochemistry
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- 2021
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Crystal structures of NUDT15 variants enabled by a potent inhibitor reveal the structural basis for thiopurine sensitivity
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- Contribution to journal › Article
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Structure of the native pyruvate dehydrogenase complex reveals the mechanism of substrate insertion
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- Contribution to journal › Article
- 2020
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Structure and steroid isomerase activity of Drosophila glutathione transferase E14 essential for ecdysteroid biosynthesis
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- Contribution to journal › Article
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The first structure of an active mammalian dCTPase and its complexes with substrate analogues and products
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- Contribution to journal › Article
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Massively parallel variant characterization identifies NUDT15 alleles associated with thiopurine toxicity
2020) In Proceedings of the National Academy of Sciences of the United States of America 117(10). p.5394-5401(
- Contribution to journal › Article
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Synaptotagmin binding to botulinum neurotoxins
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- Contribution to journal › Article
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Targeting OGG1 arrests cancer cell proliferation by inducing replication stress
2020) In Nucleic Acids Research(
- Contribution to journal › Article
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Development of a chemical probe against NUDT15
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- Contribution to journal › Article
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Structural and Biochemical Characterization of Botulinum Neurotoxin Subtype B2 Binding to Its Receptors
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- Contribution to journal › Article
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A ribonucleotide reductase from Clostridium botulinum reveals distinct evolutionary pathways to regulation via the overall activity site
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- Contribution to journal › Article