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2022
Mark Pharmacological OGG1 inhibition decreases murine allergic airway inflammation
Tanner, Lloyd ^LU ; Bergwik, Jesper ^LU ; Bhongir, Ravi K. V. ^LU ; Pan, Lang ; Dong, Caijuan ; Wallner, Olov ; Kalderén, Christina ; Helleday, Thomas ; Boldogh, Istvan and Adner, Mikael ^LU , et al. (2022) In Frontiers in Pharmacology 13.
- Contribution to journal › Article
Mark Optimization of N-Piperidinyl-Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8-Oxo-Guanine DNA Glycosylase 1
Wallner, Olov ; Cázares-Körner, Armando ; Scaletti, Emma Rose ; Masuyer, Geoffrey ; Bekkhus, Tove ; Visnes, Torkild ; Mamonov, Kirill ; Ortis, Florian ; Lundbäck, Thomas and Volkova, Maria , et al. (2022) In ChemMedChem
- Contribution to journal › Article
2021
Mark Crystal structures of NUDT15 variants enabled by a potent inhibitor reveal the structural basis for thiopurine sensitivity
Rehling, Daniel ; Zhang, Si Min ; Jemth, Ann-Sofie ; Koolmeister, Tobias ; Throup, Adam ; Wallner, Olov ; Scaletti, Emma ^LU ; Moriyama, Takaya ; Nishii, Rina and Davies, Jonathan , et al. (2021) In The Journal of biological chemistry 296.
- Contribution to journal › Article
Mark NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir
Zhang, Si Min ; Rehling, Daniel ; Jemth, Ann-Sofie ; Throup, Adam ; Landázuri, Natalia ; Almlöf, Ingrid ; Göttmann, Mona ; Valerie, Nicholas C K ; Borhade, Sanjay R and Wakchaure, Prasad , et al. (2021) In Cell Chemical Biology 28(12). p.6-1702
- Contribution to journal › Article
2020
Mark The first structure of an active mammalian dCTPase and its complexes with substrate analogues and products
Scaletti, Emma ^LU ; Claesson, Magnus ; Helleday, Thomas ; Jemth, Ann-Sofie and Stenmark, Pål ^LU (2020) In Journal of Molecular Biology 432(4). p.1126-1142
- Contribution to journal › Article
Mark Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target
Škerlová, Jana ; Unterlass, Judith ; Göttmann, Mona ; Marttila, Petra ; Homan, Evert ; Helleday, Thomas ; Jemth, Ann-Sofie and Stenmark, Pål ^LU (2020) In Journal of Biological Chemistry 295(33). p.11656-11668
- Contribution to journal › Article
Mark MutT homologue 1 (MTH1) removes N6-methyl-dATP from the dNTP pool
Scaletti, Emma Rose ^LU ; Vallin, Karl S ; Bräutigam, Lars ; Sarno, Antonio ; Berglund, Ulrika Warpman ; Helleday, Thomas ; Stenmark, Pål ^LU and Jemth, Ann-Sofie (2020) In Journal of Biological Chemistry 295(15). p.4761-4772
- Contribution to journal › Article
Mark Broadly Active Antiviral Compounds Disturb Zika Virus Progeny Release Rescuing Virus-Induced Toxicity in Brain Organoids
Pettke, Aleksandra ; Tampere, Marianna ; Pronk, Robin ; Wallner, Olov ; Falk, Anna ^LU ; Warpman Berglund, Ulrika ; Helleday, Thomas ; Mirazimi, Ali and Puumalainen, Marjo-Riitta (2020) In Viruses 13(1).
- Contribution to journal › Article
Mark Development of a chemical probe against NUDT15
Zhang, Si Min ; Desroses, Matthieu ; Hagenkort, Anna ; Valerie, Nicholas C K ; Rehling, Daniel ; Carter, Megan ; Wallner, Olov ; Koolmeister, Tobias ; Throup, Adam and Jemth, Ann-Sofie , et al. (2020) In Nature Chemical Biology 16(10). p.1120-1128
- Contribution to journal › Article
Mark Targeting OGG1 arrests cancer cell proliferation by inducing replication stress
Visnes, Torkild ; Benítez-Buelga, Carlos ; Cázares-Körner, Armando ; Sanjiv, Kumar ; Hanna, Bishoy M F ; Mortusewicz, Oliver ; Rajagopal, Varshni ; Albers, Julian J ; Hagey, Daniel W and Bekkhus, Tove , et al. (2020) In Nucleic Acids Research
- Contribution to journal › Article

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