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2021
Mark NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir
Zhang, Si Min ; Rehling, Daniel ; Jemth, Ann-Sofie ; Throup, Adam ; Landázuri, Natalia ; Almlöf, Ingrid ; Göttmann, Mona ; Valerie, Nicholas C K ; Borhade, Sanjay R and Wakchaure, Prasad , et al. (2021) In Cell Chemical Biology 28(12). p.6-1702
- Contribution to journal › Article
2020
Mark Development of a chemical probe against NUDT15
Zhang, Si Min ; Desroses, Matthieu ; Hagenkort, Anna ; Valerie, Nicholas C K ; Rehling, Daniel ; Carter, Megan ; Wallner, Olov ; Koolmeister, Tobias ; Throup, Adam and Jemth, Ann-Sofie , et al. (2020) In Nature Chemical Biology 16(10). p.1120-1128
- Contribution to journal › Article
Mark Targeting OGG1 arrests cancer cell proliferation by inducing replication stress
Visnes, Torkild ; Benítez-Buelga, Carlos ; Cázares-Körner, Armando ; Sanjiv, Kumar ; Hanna, Bishoy M F ; Mortusewicz, Oliver ; Rajagopal, Varshni ; Albers, Julian J ; Hagey, Daniel W and Bekkhus, Tove , et al. (2020) In Nucleic Acids Research
- Contribution to journal › Article
2018
Mark Crystal Structures and Inhibitor Interactions of Mouse and Dog MTH1 Reveal Species-Specific Differences in Affinity
Narwal, Mohit ; Jemth, Ann-Sofie ; Gustafsson, Robert ; Almlöf, Ingrid ; Warpman Berglund, Ulrika ; Helleday, Thomas and Stenmark, Pål ^LU (2018) In Biochemistry 57(5). p.593-603
- Contribution to journal › Article
Mark MutT homologue 1 (MTH1) catalyzes the hydrolysis of mutagenic O6-methyl-dGTP
Jemth, Ann-Sofie ; Gustafsson, Robert ; Bräutigam, Lars ; Henriksson, Linda ; Vallin, Karl S A ; Sarno, Antonio ; Almlöf, Ingrid ; Homan, Evert ; Rasti, Azita and Warpman Berglund, Ulrika , et al. (2018) In Nucleic Acids Research 46(20). p.10888-10904
- Contribution to journal › Article
Mark Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
Page, Brent D G ; Valerie, Nicholas C K ; Wright, Roni H G ; Wallner, Olov ; Isaksson, Rebecka ; Carter, Megan ; Rudd, Sean G ; Loseva, Olga ; Jemth, Ann-Sofie and Almlöf, Ingrid , et al. (2018) In Nature Communications 9(1).
- Contribution to journal › Article
2017
Mark Fragment-Based Discovery and Optimization of Enzyme Inhibitors by Docking of Commercial Chemical Space
Rudling, Axel ; Gustafsson, Robert ; Almlöf, Ingrid ; Homan, Evert ; Scobie, Martin ; Warpman Berglund, Ulrika ; Helleday, Thomas ; Stenmark, Pål ^LU and Carlsson, Jens (2017) In Journal of Medicinal Chemistry 60(19). p.8160-8169
- Contribution to journal › Article