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- 2023
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Mark
Optimization of N-Piperidinyl-Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8-Oxo-Guanine DNA Glycosylase 1
(
- Contribution to journal › Article
- 2022
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Mark
Pharmacological OGG1 inhibition decreases murine allergic airway inflammation
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- Contribution to journal › Article
- 2021
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Mark
Crystal structures of NUDT15 variants enabled by a potent inhibitor reveal the structural basis for thiopurine sensitivity
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- Contribution to journal › Article
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Mark
NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir
(
- Contribution to journal › Article
- 2020
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Mark
The first structure of an active mammalian dCTPase and its complexes with substrate analogues and products
(
- Contribution to journal › Article
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Mark
Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target
(
- Contribution to journal › Article
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Mark
MutT homologue 1 (MTH1) removes N6-methyl-dATP from the dNTP pool
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- Contribution to journal › Article
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Mark
Broadly Active Antiviral Compounds Disturb Zika Virus Progeny Release Rescuing Virus-Induced Toxicity in Brain Organoids
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- Contribution to journal › Article
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Mark
Development of a chemical probe against NUDT15
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- Contribution to journal › Article
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Mark
Targeting OGG1 arrests cancer cell proliferation by inducing replication stress
2020) In Nucleic Acids Research(
- Contribution to journal › Article
- 2019
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Mark
Structural basis of inhibition of the human serine hydroxymethyltransferase SHMT2 by antifolate drugs
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- Contribution to journal › Article
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Mark
Crystal Structure and Substrate Specificity of the 8-oxo-dGTP Hydrolase NUDT1 from Arabidopsis thaliana
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- Contribution to journal › Article
- 2018
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Mark
Crystal Structures and Inhibitor Interactions of Mouse and Dog MTH1 Reveal Species-Specific Differences in Affinity
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- Contribution to journal › Article
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Mark
Human NUDT22 Is a UDP-Glucose/Galactose Hydrolase Exhibiting a Unique Structural Fold
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- Contribution to journal › Article
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Mark
MutT homologue 1 (MTH1) catalyzes the hydrolysis of mutagenic O6-methyl-dGTP
(
- Contribution to journal › Article