Structural Biochemistry
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- 2021
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Mark
Structural and functional analysis of the inhibition of equine glutathione transferase A3-3 by organotin endocrine disrupting pollutants
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- Contribution to journal › Article
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Mark
NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir
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- Contribution to journal › Article
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Mark
NUDT15 polymorphism influences the metabolism and therapeutic effects of acyclovir and ganciclovir
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- Contribution to journal › Article
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Mark
Mechanism of Ganglioside Receptor Recognition by Botulinum Neurotoxin Serotype E
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- Contribution to journal › Article
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Mark
Re-engineering Botox : Botulinum neurotoxin is altered to recognize a different substrate
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- Contribution to journal › Debate/Note/Editorial
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Mark
Crystal structures of NUDT15 variants enabled by a potent inhibitor reveal the structural basis for thiopurine sensitivity
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- Contribution to journal › Article
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Mark
Structure of the native pyruvate dehydrogenase complex reveals the mechanism of substrate insertion
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- Contribution to journal › Article
- 2020
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Mark
Structure and steroid isomerase activity of Drosophila glutathione transferase E14 essential for ecdysteroid biosynthesis
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- Contribution to journal › Article
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Mark
Massively parallel variant characterization identifies NUDT15 alleles associated with thiopurine toxicity
2020) In Proceedings of the National Academy of Sciences of the United States of America 117(10). p.5394-5401(
- Contribution to journal › Article
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Mark
A ribonucleotide reductase from Clostridium botulinum reveals distinct evolutionary pathways to regulation via the overall activity site
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- Contribution to journal › Article