Patrick MacDonald (Former)

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2020
Mark Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D
Viñuela, Ana ; Varshney, Arushi ; van de Bunt, Martijn ; Prasad, Rashmi B ^LU ; Asplund, Olof ^LU ; Bennett, Amanda ; Boehnke, Michael ; Brown, Andrew A ; Erdos, Michael R and Fadista, João ^LU , et al. (2020) In Nature Communications 11(1). p.4912-4912
- Contribution to journal › Article
2007
Mark Corelease and differential exit via the fusion pore of GABA, serotonin, and ATP from LDCV in rat pancreatic beta cells
Braun, Matthias ^LU ; Wendt, Anna ^LU ; Karanauskaite, Jovita ^LU ; Galvanovskis, Juris ^LU ; Clark, Anne ; MacDonald, Patrick ^LU and Rorsman, Patrik ^LU (2007) In Journal of General Physiology 129(3). p.221-231
- Contribution to journal › Article
2006
Mark Role of phosphatidylinositol 3-kinase gamma in the beta-cell: Interactions with glucagon-like peptide-1
Li, LX ; MacDonald, Patrick ^LU ; Ahn, DS ; Oudit, GY ; Backx, PH and Brubaker, PL (2006) In Endocrinology 147(7). p.3318-3325
- Contribution to journal › Article
2005
Mark Calcium increases endocytotic vesicle size and accelerates membrane fission in insulin-secreting INS-1 cells.
MacDonald, Patrick ^LU ; Eliasson, Lena ^LU and Rorsman, Patrik ^LU (2005) In Journal of Cell Science 118(Pt 24). p.5911-5920
- Contribution to journal › Article
Mark Glucose-sensing mechanisms in pancreatic beta-cells
MacDonald, Patrick ^LU ; Joseph, JW and Rorsman, Patrik ^LU (2005) In Philosophical Transactions of the Royal Society B: Biological Sciences 360(1464). p.2211-2225
- Contribution to journal › Article
Mark Regulated Exocytosis and Kiss-and-Run of Synaptic-Like Microvesicles in INS-1 and Primary Rat {beta}-Cells.
MacDonald, Patrick ^LU ; Obermüller, Stefanie ^LU ; Vikman, Jenny ^LU ; Galvanovskis, Juris ^LU ; Rorsman, Patrik ^LU and Eliasson, Lena ^LU (2005) In Diabetes 54(3). p.736-743
- Contribution to journal › Article
2004
Mark Impaired glucose-stimulated insulin secretion, enhanced IP insulin tolerance and increased {beta}-cell mass in mice lacking the p110{gamma} isoform of PI3-kinase.
MacDonald, Patrick ^LU ; Joseph, J. W. ; Yau, D. ; Diao, J. ; Asghar, Z. ; Dai, F. ; Oudit, G. Y. ; Patel, M. M. ; Backx, P. H. and Wheeler, M. B. (2004) In Endocrinology 145(9). p.4078-4083
- Contribution to journal › Article
Mark A pancreatic islet-specific microRNA regulates insulin secretion
Poy, MN ; Eliasson, Lena ^LU ; Krutzfeldt, J ; Kuwajima, S ; Ma, Xiaosong ^LU ; MacDonald, Patrick ^LU ; Pfeffer, B ; Tuschl, T ; Rajewsky, N and Rorsman, Patrik ^LU , et al. (2004) In Nature 432(7014). p.226-230
- Contribution to journal › Article
2003
Mark Antagonism of rat beta -cell voltage-dependent K+ currents by exendin-4 requires dual activation of the cAMP/PKA and PI3 kinase signalling pathways.
MacDonald, Patrick ^LU ; Wang, Xiaolin ; Xia, Fuzhen ; El-Kholy, Wasim ; Targonsky, Elisha ; Tsushima, Robert G. and Wheeler, Michael B. (2003) In Journal of Biological Chemistry 278(52). p.52446-52453
- Contribution to journal › Article