Peter Ellmark

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2022
Mark Bispecific antibodies targeting CD40 and tumor-associated antigens promote cross-priming of T cells resulting in an antitumor response superior to monospecific antibodies
Hägerbrand, Karin ^LU ; Varas, Laura ^LU ; Deronic, Adnan ^LU ; Nyesiga, Barnabas ; Sundstedt, Anette ^LU ; Ljung, Lill ; Sakellariou, Christina ^LU ; Werchau, Doreen ; Thagesson, Mia and Gomez Jimenez, David ^LU , et al. (2022) In Journal for ImmunoTherapy of Cancer 10(11).
- Contribution to journal › Article
Mark Transcriptional profiling demonstrates altered characteristics of CD8 + cytotoxic T-cells and regulatory T-cells in TP53-mutated acute myeloid leukemia
Abolhalaj, Milad ^LU ; Sincic, Viktor ^LU ; Lilljebjörn, Henrik ^LU ; Sandén, Carl ^LU ; Aab, Alar ^LU ; Hägerbrand, Karin ^LU ; Ellmark, Peter ^LU ; Borrebaeck, Carl ^LU ; Fioretos, Thoas ^LU and Lundberg, Kristina ^LU (2022) In Cancer Medicine 11(15). p.3023-3032
- Contribution to journal › Article
2021
Mark CD137 (4-1BB) costimulation of CD8⁺ T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation
Otano, Itziar ; Azpilikueta, Arantza ; Glez-Vaz, Javier ; Alvarez, Maite ; Medina-Echeverz, José ; Cortés-Domínguez, Ivan ; Ortiz-de-Solorzano, Carlos ; Ellmark, Peter ^LU ; Fritzell, Sara ^LU and Hernandez-Hoyos, Gabriela , et al. (2021) In Nature Communications 12(1).
- Contribution to journal › Article
Mark Rationale and clinical development of CD40 agonistic antibodies for cancer immunotherapy
Enell Smith, Karin ^LU ; Deronic, Adnan ^LU ; Hägerbrand, Karin ^LU ; Norlén, Per ^LU and Ellmark, Peter ^LU (2021) In Expert Opinion on Biological Therapy 21(12). p.1635-1646
- Contribution to journal › Scientific review
Mark The human anti-CD40 agonist antibody mitazalimab (ADC-1013; JNJ-64457107) activates antigen-presenting cells, improves expansion of antigen-specific T cells, and enhances anti-tumor efficacy of a model cancer vaccine in vivo
Deronic, Adnan ^LU ; Nilsson, Anneli ; Thagesson, Mia ; Werchau, Doreen ; Enell Smith, Karin ^LU and Ellmark, Peter ^LU (2021) In Cancer Immunology, Immunotherapy 70(12). p.3629-3642
- Contribution to journal › Article
2020
Mark Transcriptomic profiling of T-cell populations in non-muscle invasive and muscle invasive bladder cancer.
Sincic, Viktor ^LU ; Abolhalaj, Milad ^LU ; Lilljebjörn, Henrik ^LU ; Aab, Alar ^LU ; Hägerbrand, Karin ^LU ; Ellmark, Peter ^LU ; Fioretos, Thoas ^LU ; Borrebaeck, Carl ^LU ; Liedberg, Fredrik ^LU and Lundberg, Kristina ^LU (2020) The Society for Immunotherapy of Cancer's (SITC) 35th annual meeting In Journal for ImmunoTherapy of Cancer 8(Suppl. 3).
- Contribution to journal › Published meeting abstract
Mark Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy
Georganaki, Maria ; Ramachandran, Mohanraj ; Tuit, Sander ; Núñez, Nicolás Gonzalo ; Karampatzakis, Alexandros ; Fotaki, Grammatiki ; van Hooren, Luuk ; Huang, Hua ; Lugano, Roberta and Ulas, Thomas , et al. (2020) In OncoImmunology 9(1).
- Contribution to journal › Article
2019
Mark The CTLA-4 x OX40 bispecific antibody ATOR-1015 induces anti-tumor effects through tumor-directed immune activation
Kvarnhammar, Anne Månsson ; Veitonmäki, Niina ; Hägerbrand, Karin ^LU ; Dahlman, Anna ^LU ; Smith, Karin Enell ^LU ; Fritzell, Sara ^LU ; Von Schantz, Laura ^LU ; Thagesson, Mia ; Werchau, Doreen and Smedenfors, Kristine , et al. (2019) In Journal for ImmunoTherapy of Cancer 7(1).
- Contribution to journal › Article
Mark First-in-human study with intratumoral administration of a CD40 agonistic antibody, ADC-1013, in advanced solid malignancies
Irenaeus, Sandra M.M. ; Nielsen, Dorte ; Ellmark, Peter ^LU ; Yachnin, Jeffrey ; Deronic, Adnan ^LU ; Nilsson, Anneli ^LU ; Norlén, Per ^LU ; Veitonmäki, Niina ; Wennersten, Camilla S. and Ullenhag, Gustav J. (2019) In International Journal of Cancer 145(5). p.1189-1199
- Contribution to journal › Article
2018
Mark Administration of low-dose combination anti-CTLA4, anti-CD137, and anti-OX40 into murine tumor or proximal to the tumor draining lymph node induces systemic tumor regression
Hebb, Jonathan P.O. ; Mosley, Adriane R. ; Vences-Catalán, Felipe ; Rajasekaran, Narendiran ; Rosén, Anna ; Ellmark, Peter ^LU and Felsher, Dean W. (2018) In Cancer Immunology, Immunotherapy 67(1). p.47-60
- Contribution to journal › Article