Salam Al-Karadaghi

Biochemistry and Structural Biology

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2022
Mark Crystal structure of DNA polymerase I from Thermus phage G20c
Ahlqvist, Josefin ^LU ; Linares-Pastén, Javier A. ^LU ; Jasilionis, Andrius ^LU ; Welin, Martin ^LU ; Håkansson, Maria ^LU ; Svensson, L. Anders ; Wang, Lei ^LU ; Watzlawick, Hildegard ; Ævarsson, Arnþór and Friðjónsson, Ólafur H. , et al. (2022) In Acta crystallographica. Section D, Structural biology 78(Pt 11). p.1384-1398
- Contribution to journal › Article
Mark Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold : SAR of the Aryloxyaryl Moiety
Sainas, Stefano ; Giorgis, Marta ; Circosta, Paola ; Poli, Giulio ; Alberti, Marta ; Passoni, Alice ; Gaidano, Valentina ; Pippione, Agnese C. ; Vitale, Nicoletta and Bonanni, Davide , et al. (2022) In Journal of Medicinal Chemistry 65(19). p.12701-12724
- Contribution to journal › Article
Mark Crystal structure and initial characterization of a novel archaeal-like Holliday junction-resolving enzyme from Thermus thermophilus phage Tth15-6
Ahlqvist, Josefin ^LU ; Linares-Pastén, Javier A ^LU ; Håkansson, Maria ^LU ; Jasilionis, Andrius ^LU ; Kwiatkowska-Semrau, Karolina ; Friðjónsson, Ólafur H. ; Kaczorowska, Anna-Karina ; Dabrowski, Slawomir ; Ævarsson, Arnþór and Hreggviðsson, Guðmundur Ó. , et al. (2022) In Acta crystallographica. Section D, Structural biology 78(Pt 2). p.212-227
- Contribution to journal › Article
2021
Mark Going to extremes - a metagenomic journey into the dark matter of life
Aevarsson, Arnthór ; Kaczorowska, Anna-Karina ; Adalsteinsson, Björn Thor ; Ahlqvist, Josefin ^LU ; Al-Karadaghi, Salam ^LU ; Altenbuchner, Joseph ; Arsin, Hasan ; Átlasson, Úlfur Áugúst ; Brandt, David and Cichowicz-Cieślak, Magdalena , et al. (2021) In FEMS Microbiology Letters 368(12).
- Contribution to journal › Scientific review
Mark Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold : SAR of the Biphenyl Moiety
Sainas, Stefano ; Giorgis, Marta ; Circosta, Paola ; Gaidano, Valentina ; Bonanni, Davide ; Pippione, Agnese C. ; Bagnati, Renzo ; Passoni, Alice ; Qiu, Yaqi and Cojocaru, Carina Florina , et al. (2021) In Journal of Medicinal Chemistry 64(9). p.5404-5428
- Contribution to journal › Article
2019
Mark Hydroxyazole scaffold-based Plasmodium falciparum dihydroorotate dehydrogenase inhibitors : Synthesis, biological evaluation and X-ray structural studies
Pippione, Agnese C. ; Sainas, Stefano ; Goyal, Parveen ; Fritzson, Ingela ^LU ; Cassiano, Gustavo C. ; Giraudo, Alessandro ; Giorgis, Marta ; Tavella, Tatyana A. ; Bagnati, Renzo and Rolando, Barbara , et al. (2019) In European Journal of Medicinal Chemistry 163. p.266-280
- Contribution to journal › Article
2018
Mark Structural modelling of the DNAJB6 oligomeric chaperone shows a peptide-binding cleft lined with conserved S/T-residues at the dimer interface
Söderberg, Christopher A.G. ^LU ; Månsson, Cecilia ^LU ; Bernfur, Katja ^LU ; Rutsdottir, Gudrun ^LU ; Härmark, Johan ; Rajan, Sreekanth ^LU ; Al-Karadaghi, Salam ^LU ; Rasmussen, Morten ; Höjrup, Peter and Hebert, Hans ^LU , et al. (2018) In Scientific Reports 8(1).
- Contribution to journal › Article
2017
Mark Iron-induced oligomerization of human FXN^81-210 and bacterial CyaY frataxin and the effect of iron chelators
Ahlgren, Eva Christina ^LU ; Fekry, Mostafa ; Wiemann, Mathias ; Söderberg, Christopher A. ^LU ; Bernfur, Katja ^LU ; Gakh, Olex ; Rasmussen, Morten ; Højrup, Peter ; Emanuelsson, Cecilia ^LU and Isaya, Grazia , et al. (2017) In PLoS ONE 12(12).
- Contribution to journal › Article
Mark Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds
Sainas, Stefano ; Pippione, Agnese C. ; Giorgis, Marta ; Lupino, Elisa ; Goyal, Parveen ; Ramondetti, Cristina ; Buccinnà, Barbara ; Piccinini, Marco ; Braga, Rodolpho C. and Andrade, Carolina H. , et al. (2017) In European Journal of Medicinal Chemistry 129. p.287-302
- Contribution to journal › Article
Mark SAXS and stability studies of iron-induced oligomers of bacterial frataxin CyaY
Fekry, Mostafa ; Alshokry, Wessen ; Grela, Przemysław ; Tchórzewski, Marek ^LU ; Ahlgren, Eva Christina ^LU ; Söderberg, Christopher A. ^LU ; Gakh, Oleksandr ; Isaya, Grazia and Al-Karadaghi, Salam ^LU (2017) In PLoS ONE 12(9). p.0184961-0184961
- Contribution to journal › Article

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