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Coffee and tea consumption and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition

Sen, Abhijit; Papadimitriou, Nikos; Lagiou, Pagona; Perez-Cornago, Aurora; Travis, Ruth C.; Key, Timothy J.; Murphy, Neil; Gunter, Marc; Freisling, Heinz and Tzoulaki, Ioanna, et al. (2019) In International Journal of Cancer 144(2). p.240-250
Abstract

The epidemiological evidence regarding the association of coffee and tea consumption with prostate cancer risk is inconclusive, and few cohort studies have assessed these associations by disease stage and grade. We examined the associations of coffee (total, caffeinated and decaffeinated) and tea intake with prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition. Among 142,196 men, 7,036 incident prostate cancer cases were diagnosed over 14 years of follow-up. Data on coffee and tea consumption were collected through validated country-specific food questionnaires at baseline. We used Cox proportional hazards regression models to compute hazard ratios (HRs) and 95% confidence intervals (CI). Models were... (More)

The epidemiological evidence regarding the association of coffee and tea consumption with prostate cancer risk is inconclusive, and few cohort studies have assessed these associations by disease stage and grade. We examined the associations of coffee (total, caffeinated and decaffeinated) and tea intake with prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition. Among 142,196 men, 7,036 incident prostate cancer cases were diagnosed over 14 years of follow-up. Data on coffee and tea consumption were collected through validated country-specific food questionnaires at baseline. We used Cox proportional hazards regression models to compute hazard ratios (HRs) and 95% confidence intervals (CI). Models were stratified by center and age, and adjusted for anthropometric, lifestyle and dietary factors. Median coffee and tea intake were 375 and 106 mL/day, respectively, but large variations existed by country. Comparing the highest (median of 855 mL/day) versus lowest (median of 103 mL/day) consumers of coffee and tea (450 vs. 12 mL/day) the HRs were 1.02 (95% CI, 0.94–1.09) and 0.98 (95% CI, 0.90–1.07) for risk of total prostate cancer and 0.97 (95% CI, 0.79–1.21) and 0.89 (95% CI, 0.70–1.13) for risk of fatal disease, respectively. No evidence of association was seen for consumption of total, caffeinated or decaffeinated coffee or tea and risk of total prostate cancer or cancer by stage, grade or fatality in this large cohort. Further investigations are needed to clarify whether an association exists by different preparations or by concentrations and constituents of these beverages.

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published
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keywords
caffeinated, coffee, decaffeinated, EPIC, prostate cancer, tea
in
International Journal of Cancer
volume
144
issue
2
pages
240 - 250
publisher
John Wiley & Sons
external identifiers
  • scopus:85056735946
ISSN
0020-7136
DOI
10.1002/ijc.31634
language
English
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yes
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0b1420dc-5390-47a1-8909-abbb8a3d133a
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2018-11-29 08:56:59
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2019-02-26 11:21:45
@article{0b1420dc-5390-47a1-8909-abbb8a3d133a,
  abstract     = {<p>The epidemiological evidence regarding the association of coffee and tea consumption with prostate cancer risk is inconclusive, and few cohort studies have assessed these associations by disease stage and grade. We examined the associations of coffee (total, caffeinated and decaffeinated) and tea intake with prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition. Among 142,196 men, 7,036 incident prostate cancer cases were diagnosed over 14 years of follow-up. Data on coffee and tea consumption were collected through validated country-specific food questionnaires at baseline. We used Cox proportional hazards regression models to compute hazard ratios (HRs) and 95% confidence intervals (CI). Models were stratified by center and age, and adjusted for anthropometric, lifestyle and dietary factors. Median coffee and tea intake were 375 and 106 mL/day, respectively, but large variations existed by country. Comparing the highest (median of 855 mL/day) versus lowest (median of 103 mL/day) consumers of coffee and tea (450 vs. 12 mL/day) the HRs were 1.02 (95% CI, 0.94–1.09) and 0.98 (95% CI, 0.90–1.07) for risk of total prostate cancer and 0.97 (95% CI, 0.79–1.21) and 0.89 (95% CI, 0.70–1.13) for risk of fatal disease, respectively. No evidence of association was seen for consumption of total, caffeinated or decaffeinated coffee or tea and risk of total prostate cancer or cancer by stage, grade or fatality in this large cohort. Further investigations are needed to clarify whether an association exists by different preparations or by concentrations and constituents of these beverages.</p>},
  author       = {Sen, Abhijit and Papadimitriou, Nikos and Lagiou, Pagona and Perez-Cornago, Aurora and Travis, Ruth C. and Key, Timothy J. and Murphy, Neil and Gunter, Marc and Freisling, Heinz and Tzoulaki, Ioanna and Muller, David C. and Cross, Amanda J. and Lopez, David S. and Bergmann, Manuela and Boeing, Heiner and Bamia, Christina and Kotanidou, Anastasia and Karakatsani, Anna and Tjønneland, Anne and Kyrø, Cecilie and Outzen, Malene and Redondo, María Luisa and Cayssials, Valerie and Chirlaque, Maria Dolores and Barricarte, Aurelio and Sánchez, Maria Jose and Larrañaga, Nerea and Tumino, Rosario and Grioni, Sara and Palli, Domenico and Caini, Saverio and Sacerdote, Carlotta and Bueno-de-Mesquita, Bas and Kühn, Tilman and Kaaks, Rudolf and Nilsson, Lena Maria and Landberg, Rikard and Wallström, Peter and Drake, Isabel and Bech, Bodil Hammer and Overvad, Kim and Aune, Dagfinn and Khaw, Kay Tee and Riboli, Elio and Trichopoulos, Dimitrios and Trichopoulou, Antonia and Tsilidis, Konstantinos K.},
  issn         = {0020-7136},
  keyword      = {caffeinated,coffee,decaffeinated,EPIC,prostate cancer,tea},
  language     = {eng},
  number       = {2},
  pages        = {240--250},
  publisher    = {John Wiley & Sons},
  series       = {International Journal of Cancer},
  title        = {Coffee and tea consumption and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition},
  url          = {http://dx.doi.org/10.1002/ijc.31634},
  volume       = {144},
  year         = {2019},
}