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Inhibition of ConA-induced proliferative response in human lymphocytes by podophyllotoxin and a detergent, Tween80

Månsson, Bengt LU ; Geborek, Pierre LU ; Hallberg, T and Sturfelt, Gunnar LU (1988) In Clinical and Experimental Rheumatology 6(4). p.405-407
Abstract
Podophyllotoxin (CPH86), at concentrations of 5 ng/ml or more, inhibited [3H]-thymidine uptake of ConA-induced proliferation of human peripheral mononuclear blood cells. Tween80, the detergent included in the anti-inflammatory drug Proresid, containing podophyllum lignan derivatives, also inhibited lymphocyte proliferation in a dose-dependent manner. Combination of the two drugs did not, or did only weakly, potentiate the inhibitory effect of each drug.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Clinical and Experimental Rheumatology
volume
6
issue
4
pages
405 - 407
publisher
Pacini
external identifiers
  • pmid:3229031
ISSN
1593-098X
language
English
LU publication?
yes
id
1e9713ca-a79d-4e09-bd4f-dc1734300b14 (old id 1104258)
date added to LUP
2008-08-07 13:26:06
date last changed
2016-04-15 20:15:30
@article{1e9713ca-a79d-4e09-bd4f-dc1734300b14,
  abstract     = {Podophyllotoxin (CPH86), at concentrations of 5 ng/ml or more, inhibited [3H]-thymidine uptake of ConA-induced proliferation of human peripheral mononuclear blood cells. Tween80, the detergent included in the anti-inflammatory drug Proresid, containing podophyllum lignan derivatives, also inhibited lymphocyte proliferation in a dose-dependent manner. Combination of the two drugs did not, or did only weakly, potentiate the inhibitory effect of each drug.},
  author       = {Månsson, Bengt and Geborek, Pierre and Hallberg, T and Sturfelt, Gunnar},
  issn         = {1593-098X},
  language     = {eng},
  number       = {4},
  pages        = {405--407},
  publisher    = {Pacini},
  series       = {Clinical and Experimental Rheumatology},
  title        = {Inhibition of ConA-induced proliferative response in human lymphocytes by podophyllotoxin and a detergent, Tween80},
  volume       = {6},
  year         = {1988},
}