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Beta camera low activity tumor imaging

Ljunggren, Kaj LU ; Strand, Sven-Erik LU ; Ceberg, Crister LU ; Sjöholm, Hans; Elmqvist, Dan; Brun, Arne LU and Salford, Leif LU (1993) In Acta Oncologica 32(7-8). p.869-872
Abstract
A new technique, the beta camera, to complement film autoradiography, with fast quantitative imaging of beta particle-emitting radionuclides has been developed. It consists of a thin plastic scintillator and a light-sensitive microchannel plate detector. The thin tissue sample is mounted on the scintillator. Our first system had a high background and a moderate spatial resolution of 900 microns. We now report an improved system with a photomultiplier tube mounted on the scintillator of the microchannel plate detector. Only events registered by both detectors are accepted. A fast coincidence unit processes the signals, and if a time overlap exists, an event is generated in the beta camera. In the coincidence mode, images with low activity... (More)
A new technique, the beta camera, to complement film autoradiography, with fast quantitative imaging of beta particle-emitting radionuclides has been developed. It consists of a thin plastic scintillator and a light-sensitive microchannel plate detector. The thin tissue sample is mounted on the scintillator. Our first system had a high background and a moderate spatial resolution of 900 microns. We now report an improved system with a photomultiplier tube mounted on the scintillator of the microchannel plate detector. Only events registered by both detectors are accepted. A fast coincidence unit processes the signals, and if a time overlap exists, an event is generated in the beta camera. In the coincidence mode, images with low activity distribution of 201Tl (count rate 1 s-1) in 50 microns-thick slices of a human glioma tumor could be recorded with a spatial resolution of 500 microns. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Oncologica
volume
32
issue
7-8
pages
869 - 872
publisher
Taylor & Francis
external identifiers
  • pmid:8305238
  • scopus:0027716103
ISSN
1651-226X
DOI
10.3109/02841869309096148
language
English
LU publication?
yes
id
2ea0f501-15e5-4dbe-a2f4-14bae7ead844 (old id 1107461)
date added to LUP
2008-07-31 09:29:09
date last changed
2017-01-01 06:39:56
@article{2ea0f501-15e5-4dbe-a2f4-14bae7ead844,
  abstract     = {A new technique, the beta camera, to complement film autoradiography, with fast quantitative imaging of beta particle-emitting radionuclides has been developed. It consists of a thin plastic scintillator and a light-sensitive microchannel plate detector. The thin tissue sample is mounted on the scintillator. Our first system had a high background and a moderate spatial resolution of 900 microns. We now report an improved system with a photomultiplier tube mounted on the scintillator of the microchannel plate detector. Only events registered by both detectors are accepted. A fast coincidence unit processes the signals, and if a time overlap exists, an event is generated in the beta camera. In the coincidence mode, images with low activity distribution of 201Tl (count rate 1 s-1) in 50 microns-thick slices of a human glioma tumor could be recorded with a spatial resolution of 500 microns.},
  author       = {Ljunggren, Kaj and Strand, Sven-Erik and Ceberg, Crister and Sjöholm, Hans and Elmqvist, Dan and Brun, Arne and Salford, Leif},
  issn         = {1651-226X},
  language     = {eng},
  number       = {7-8},
  pages        = {869--872},
  publisher    = {Taylor & Francis},
  series       = {Acta Oncologica},
  title        = {Beta camera low activity tumor imaging},
  url          = {http://dx.doi.org/10.3109/02841869309096148},
  volume       = {32},
  year         = {1993},
}