Beta camera low activity tumor imaging
(1993) In Acta Oncologica 32(7-8). p.869-872- Abstract
- A new technique, the beta camera, to complement film autoradiography, with fast quantitative imaging of beta particle-emitting radionuclides has been developed. It consists of a thin plastic scintillator and a light-sensitive microchannel plate detector. The thin tissue sample is mounted on the scintillator. Our first system had a high background and a moderate spatial resolution of 900 microns. We now report an improved system with a photomultiplier tube mounted on the scintillator of the microchannel plate detector. Only events registered by both detectors are accepted. A fast coincidence unit processes the signals, and if a time overlap exists, an event is generated in the beta camera. In the coincidence mode, images with low activity... (More)
- A new technique, the beta camera, to complement film autoradiography, with fast quantitative imaging of beta particle-emitting radionuclides has been developed. It consists of a thin plastic scintillator and a light-sensitive microchannel plate detector. The thin tissue sample is mounted on the scintillator. Our first system had a high background and a moderate spatial resolution of 900 microns. We now report an improved system with a photomultiplier tube mounted on the scintillator of the microchannel plate detector. Only events registered by both detectors are accepted. A fast coincidence unit processes the signals, and if a time overlap exists, an event is generated in the beta camera. In the coincidence mode, images with low activity distribution of 201Tl (count rate 1 s-1) in 50 microns-thick slices of a human glioma tumor could be recorded with a spatial resolution of 500 microns. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1107461
- author
- Ljunggren, Kaj
LU
; Strand, Sven-Erik
LU
; Ceberg, Crister
LU
; Sjöholm, Hans ; Elmqvist, Dan ; Brun, Arne LU and Salford, Leif LU
- organization
- publishing date
- 1993
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Acta Oncologica
- volume
- 32
- issue
- 7-8
- pages
- 869 - 872
- publisher
- Taylor & Francis
- external identifiers
-
- pmid:8305238
- scopus:0027716103
- ISSN
- 1651-226X
- DOI
- 10.3109/02841869309096148
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Radiation Physics, Lund (013034000), Neurosurgery (013026000), Pathology, (Lund) (013030000)
- id
- 2ea0f501-15e5-4dbe-a2f4-14bae7ead844 (old id 1107461)
- date added to LUP
- 2016-04-01 15:27:10
- date last changed
- 2021-01-03 04:01:47
@article{2ea0f501-15e5-4dbe-a2f4-14bae7ead844, abstract = {{A new technique, the beta camera, to complement film autoradiography, with fast quantitative imaging of beta particle-emitting radionuclides has been developed. It consists of a thin plastic scintillator and a light-sensitive microchannel plate detector. The thin tissue sample is mounted on the scintillator. Our first system had a high background and a moderate spatial resolution of 900 microns. We now report an improved system with a photomultiplier tube mounted on the scintillator of the microchannel plate detector. Only events registered by both detectors are accepted. A fast coincidence unit processes the signals, and if a time overlap exists, an event is generated in the beta camera. In the coincidence mode, images with low activity distribution of 201Tl (count rate 1 s-1) in 50 microns-thick slices of a human glioma tumor could be recorded with a spatial resolution of 500 microns.}}, author = {{Ljunggren, Kaj and Strand, Sven-Erik and Ceberg, Crister and Sjöholm, Hans and Elmqvist, Dan and Brun, Arne and Salford, Leif}}, issn = {{1651-226X}}, language = {{eng}}, number = {{7-8}}, pages = {{869--872}}, publisher = {{Taylor & Francis}}, series = {{Acta Oncologica}}, title = {{Beta camera low activity tumor imaging}}, url = {{http://dx.doi.org/10.3109/02841869309096148}}, doi = {{10.3109/02841869309096148}}, volume = {{32}}, year = {{1993}}, }