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Use of an enhanced gradient system for diffusion MR imaging with motion-artifact reduction

Brockstedt, Sara LU ; Thomsen, C; Wirestam, Ronnie LU ; De Poorter, J; De Wagter, C; Salford, Leif LU ; Holtås, Stig LU and Ståhlberg, Freddy LU (1995) In Acta Radiologica 36(6). p.662-670
Abstract
PURPOSE: A spin-echo diffusion-sensitized pulse sequence using high gradients (23 mT/m) is introduced. MATERIAL AND METHODS: In order to minimize motion artefacts, velocity-compensating gradients, ECG-triggering and post-processing with phase correction and raw data averaging using navigator echoes was performed. The in vitro ratio of diffusion coefficients for water and acetone was determined and the water self-diffusion coefficient at different temperatures was evaluated. The pulse sequence was tested in 7 healthy volunteers and in 2 tumour patients with astrocytomas of grades I-II and III-IV. Both single-slice and multi-slice techniques were used. RESULTS: The incorporation of phase correction clearly improved the quality of both... (More)
PURPOSE: A spin-echo diffusion-sensitized pulse sequence using high gradients (23 mT/m) is introduced. MATERIAL AND METHODS: In order to minimize motion artefacts, velocity-compensating gradients, ECG-triggering and post-processing with phase correction and raw data averaging using navigator echoes was performed. The in vitro ratio of diffusion coefficients for water and acetone was determined and the water self-diffusion coefficient at different temperatures was evaluated. The pulse sequence was tested in 7 healthy volunteers and in 2 tumour patients with astrocytomas of grades I-II and III-IV. Both single-slice and multi-slice techniques were used. RESULTS: The incorporation of phase correction clearly improved the quality of both diffusion-encoded images and the calculated diffusion maps. Mean values of the diffusion coefficients in vivo were for CSF 2.66 x 10(-9) m2/s and for white and grey matter 0.69 x 10(-9) m2/s and 0.87 x 10(-9) m2/s, respectively. CONCLUSION: Velocity-compensating gradients in combination with a high gradient strength were shown to be useful for in vivo diffusion MR imaging. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Radiologica
volume
36
issue
6
pages
662 - 670
publisher
John Wiley & Sons
external identifiers
  • pmid:8519581
  • scopus:0029400612
ISSN
1600-0455
language
English
LU publication?
yes
id
844cb989-59eb-4d49-b27e-d44a08872878 (old id 1108736)
date added to LUP
2008-07-24 15:57:26
date last changed
2017-09-10 04:37:30
@article{844cb989-59eb-4d49-b27e-d44a08872878,
  abstract     = {PURPOSE: A spin-echo diffusion-sensitized pulse sequence using high gradients (23 mT/m) is introduced. MATERIAL AND METHODS: In order to minimize motion artefacts, velocity-compensating gradients, ECG-triggering and post-processing with phase correction and raw data averaging using navigator echoes was performed. The in vitro ratio of diffusion coefficients for water and acetone was determined and the water self-diffusion coefficient at different temperatures was evaluated. The pulse sequence was tested in 7 healthy volunteers and in 2 tumour patients with astrocytomas of grades I-II and III-IV. Both single-slice and multi-slice techniques were used. RESULTS: The incorporation of phase correction clearly improved the quality of both diffusion-encoded images and the calculated diffusion maps. Mean values of the diffusion coefficients in vivo were for CSF 2.66 x 10(-9) m2/s and for white and grey matter 0.69 x 10(-9) m2/s and 0.87 x 10(-9) m2/s, respectively. CONCLUSION: Velocity-compensating gradients in combination with a high gradient strength were shown to be useful for in vivo diffusion MR imaging.},
  author       = {Brockstedt, Sara and Thomsen, C and Wirestam, Ronnie and De Poorter, J and De Wagter, C and Salford, Leif and Holtås, Stig and Ståhlberg, Freddy},
  issn         = {1600-0455},
  language     = {eng},
  number       = {6},
  pages        = {662--670},
  publisher    = {John Wiley & Sons},
  series       = {Acta Radiologica},
  title        = {Use of an enhanced gradient system for diffusion MR imaging with motion-artifact reduction},
  volume       = {36},
  year         = {1995},
}