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Modified Mediterranean diet and survival: EPIC-elderly prospective cohort study

Trichopoulou, Antonia; Orfanos, Philippos; Norat, Teresa; Bueno-de-Mesquita, Bas; Ocke, Marga C; Peeters, Petra H M; van der Schouw, Yvonne T; Boeing, Heiner; Hoffmann, Kurt and Boffetta, Paolo, et al. (2005) In BMJ (Clinical research ed.) 330(7498).
Abstract
OBJECTIVE: To examine whether adherence to the modified Mediterranean diet, in which unsaturates were substituted for monounsaturates, is associated with longer life expectancy among elderly Europeans. DESIGN: Multicentre, prospective cohort study. SETTING: Nine European countries (Denmark, France, Germany, Greece, Italy, the Netherlands, Spain, Sweden, United Kingdom). PARTICIPANTS: 74,607 men and women, aged 60 or more, without coronary heart disease, stroke, or cancer at enrolment and with complete information about dietary intake and potentially confounding variables. MAIN OUTCOME MEASURES: Extent of adherence to a modified Mediterranean diet using a scoring system on a 10 point scale, and death from any cause by time of occurrence,... (More)
OBJECTIVE: To examine whether adherence to the modified Mediterranean diet, in which unsaturates were substituted for monounsaturates, is associated with longer life expectancy among elderly Europeans. DESIGN: Multicentre, prospective cohort study. SETTING: Nine European countries (Denmark, France, Germany, Greece, Italy, the Netherlands, Spain, Sweden, United Kingdom). PARTICIPANTS: 74,607 men and women, aged 60 or more, without coronary heart disease, stroke, or cancer at enrolment and with complete information about dietary intake and potentially confounding variables. MAIN OUTCOME MEASURES: Extent of adherence to a modified Mediterranean diet using a scoring system on a 10 point scale, and death from any cause by time of occurrence, modelled through Cox regression. RESULTS: An increase in the modified Mediterranean diet score was associated with lower overall mortality, a two unit increment corresponding to a statistically significant reduction of 8% (95% confidence interval 3% to 12%). No statistically significant evidence of heterogeneity was found among countries in the association of the score with overall mortality even though the association was stronger in Greece and Spain. When dietary exposures were calibrated across countries, the reduction in mortality was 7% (1% to 12%). CONCLUSION: The Mediterranean diet, modified so as to apply across Europe, was associated with increased survival among older people. (Less)
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BMJ (Clinical research ed.)
volume
330
issue
7498
publisher
BioMed Central
external identifiers
  • pmid:15820966
  • scopus:18044368276
ISSN
1468-5833
DOI
10.1136/bmj.38415.644155.8F
language
English
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yes
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b8a5d6c1-cb73-4e97-bf9e-5a05c3019093 (old id 1133754)
date added to LUP
2008-06-17 12:38:38
date last changed
2017-11-19 04:07:16
@article{b8a5d6c1-cb73-4e97-bf9e-5a05c3019093,
  abstract     = {OBJECTIVE: To examine whether adherence to the modified Mediterranean diet, in which unsaturates were substituted for monounsaturates, is associated with longer life expectancy among elderly Europeans. DESIGN: Multicentre, prospective cohort study. SETTING: Nine European countries (Denmark, France, Germany, Greece, Italy, the Netherlands, Spain, Sweden, United Kingdom). PARTICIPANTS: 74,607 men and women, aged 60 or more, without coronary heart disease, stroke, or cancer at enrolment and with complete information about dietary intake and potentially confounding variables. MAIN OUTCOME MEASURES: Extent of adherence to a modified Mediterranean diet using a scoring system on a 10 point scale, and death from any cause by time of occurrence, modelled through Cox regression. RESULTS: An increase in the modified Mediterranean diet score was associated with lower overall mortality, a two unit increment corresponding to a statistically significant reduction of 8% (95% confidence interval 3% to 12%). No statistically significant evidence of heterogeneity was found among countries in the association of the score with overall mortality even though the association was stronger in Greece and Spain. When dietary exposures were calibrated across countries, the reduction in mortality was 7% (1% to 12%). CONCLUSION: The Mediterranean diet, modified so as to apply across Europe, was associated with increased survival among older people.},
  articleno    = {991},
  author       = {Trichopoulou, Antonia and Orfanos, Philippos and Norat, Teresa and Bueno-de-Mesquita, Bas and Ocke, Marga C and Peeters, Petra H M and van der Schouw, Yvonne T and Boeing, Heiner and Hoffmann, Kurt and Boffetta, Paolo and Nagel, Gabriele and Masala, Giovanna and Krogh, Vittorio and Panico, Sal and Tumino, Rosario and Vineis, Paolo and Bamia, Christina and Naska, Androniki and Benetou, Vassiliki and Ferrari, Pietro and Slimani, Nadia and Pera, Guillem and Martinez-Garcia, Carmen and Navarro, Carmen and Rodriguez-Barranco, Miguel and Dorronsoro, Miren and Spencer, Elizabeth A and Key, Timothy J and Bingham, Sheila and Khaw, Kay-Tee and Kesse, Emmanuelle and Clavel-Chapelon, Francoise and Boutron-Ruault,, Marie-Christine and Berglund, Göran and Wirfält, Elisabet and Hallmans, Goran and Johansson, Ingegerd and Tjonneland, Anne and Olsen, Anja and Overvad, Kim and Hundborg, Heidi H and Riboli, Elio and Trichopoulos, Dimitrios},
  issn         = {1468-5833},
  language     = {eng},
  number       = {7498},
  publisher    = {BioMed Central},
  series       = {BMJ (Clinical research ed.)},
  title        = {Modified Mediterranean diet and survival: EPIC-elderly prospective cohort study},
  url          = {http://dx.doi.org/10.1136/bmj.38415.644155.8F},
  volume       = {330},
  year         = {2005},
}