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Socker triggar våra belöningssystem. Sött frisätter opiater som sätter fart på sötsuget - insulin kan dämpa det

Erlanson-Albertsson, Charlotte LU (2005) In Läkartidningen 102(21). p.1620-1927
Abstract (Swedish)
Intag av söta livsmedel har ökat i Sverige och övriga

västvärlden. Typ av söta livsmedel har också ändrat

karaktär; sött finns idag främst som dryck – läskkonsumtionen

står i särklass över andra söta drycker.

Aptitreglering för socker har beskrivits i djurmodeller,

där det visats att opiatfrisättning triggar sockerintag i

en uppåtgående spiral. Troligen gäller samma för

människa. Sött frisätter opiater och ger smärtlindring.

Sött, särskilt som dryck, stimulerar också aptiten. Insulin

minskar konsumtionen av sött genom att blockera

opiatfrisättning, enligt djurförsök.

Sockerberoende har beskrivits i djurmodell. Med sockerlösning

som... (More)
Intag av söta livsmedel har ökat i Sverige och övriga

västvärlden. Typ av söta livsmedel har också ändrat

karaktär; sött finns idag främst som dryck – läskkonsumtionen

står i särklass över andra söta drycker.

Aptitreglering för socker har beskrivits i djurmodeller,

där det visats att opiatfrisättning triggar sockerintag i

en uppåtgående spiral. Troligen gäller samma för

människa. Sött frisätter opiater och ger smärtlindring.

Sött, särskilt som dryck, stimulerar också aptiten. Insulin

minskar konsumtionen av sött genom att blockera

opiatfrisättning, enligt djurförsök.

Sockerberoende har beskrivits i djurmodell. Med sockerlösning

som dryck utvecklades beroende, dvs ökad

konsumtion av sött, abstinenssymtom då drycken

togs bort och ångest då opiatsystemet blockerades.

Sockerberoende hos människa är ännu inte redovisat

i vetenskapliga studier. Ökat sug efter sött hos nyktra

alkoholister stöder hypotesen att socker är kraftigt belönande,

även hos människa. Utveckling av sockerberoende

kräver troligen viss genetisk uppsättning av

belöningssystemet, som är nära kopplat till beroende.

Vi bör begränsa tillgången till sött, framför allt de

söta dryckerna. Insulin och insulinkänslighet kan

vara en viktig faktor för att hejda överintag av sött. (Less)
Abstract
The consumption of sweet food has increased in Sweden, as in other Western countries. The type of food item has changed. The sweet is dominated by soft drinks. Appetite regulation for sucrose has been described in experimental animal models. It has been found that opioids stimulate appetite for sucrose. At the same time sucrose releases endogenous opioids so that a triggering of sucrose consumption occurs. Insulin has been shown to decrease sucrose intake by blocking the opioid response. Sucrose addiction has been described in rat model. With a concentrated sucrose solution to drink an opioid dependence developed with 1) increased consumption of sucrose 2) abstinence symptoms with no sucrose and 3) anxiety with an opiate blocker. Sucrose... (More)
The consumption of sweet food has increased in Sweden, as in other Western countries. The type of food item has changed. The sweet is dominated by soft drinks. Appetite regulation for sucrose has been described in experimental animal models. It has been found that opioids stimulate appetite for sucrose. At the same time sucrose releases endogenous opioids so that a triggering of sucrose consumption occurs. Insulin has been shown to decrease sucrose intake by blocking the opioid response. Sucrose addiction has been described in rat model. With a concentrated sucrose solution to drink an opioid dependence developed with 1) increased consumption of sucrose 2) abstinence symptoms with no sucrose and 3) anxiety with an opiate blocker. Sucrose addiction in man has not been described in the scientific literature. There is an increased liking of sweets with alcoholic persons, which may be significant to support a strongly rewarding effect of sucrose, also in man. We should limit the access to sweet foods, in particular the sweet drinks. Insulin and insulin sensitivity may be an important factor to restrict the intake of sweet food. (Less)
Please use this url to cite or link to this publication:
author
organization
alternative title
Sugar triggers our reward-system. Sweets release opiates which stimulates the appetite for sucrose--insulin can depress it
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Insulin: administration & dosage, Insulin: physiology, Humans, Opioid: drug effects, Receptors, Opioid: physiology, Reward, Risk Factors, Substance Withdrawal Syndrome: psychology, Taste: drug effects, Taste: physiology, Animals, Appetite: drug effects, Appetite: physiology, Beverages: adverse effects, English Abstract, Food Habits, Dietary Sucrose: adverse effects, Dietary Sucrose: administration & dosage, Brain Mapping, Candy: adverse effects, Opioid Peptides: administration & dosage, Opioid Peptides: secretion, Rats
in
Läkartidningen
volume
102
issue
21
pages
1620 - 1927
external identifiers
  • scopus:20444369530
ISSN
0023-7205
language
Swedish
LU publication?
yes
id
b95a7dcf-7a49-4bfd-b356-c43ad99cba9b (old id 1134191)
alternative location
http://ltarkiv.lakartidningen.se/2005/temp/pda30239.pdf
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15962882&dopt=Abstract
date added to LUP
2008-06-18 11:41:43
date last changed
2017-01-01 07:27:56
@article{b95a7dcf-7a49-4bfd-b356-c43ad99cba9b,
  abstract     = {The consumption of sweet food has increased in Sweden, as in other Western countries. The type of food item has changed. The sweet is dominated by soft drinks. Appetite regulation for sucrose has been described in experimental animal models. It has been found that opioids stimulate appetite for sucrose. At the same time sucrose releases endogenous opioids so that a triggering of sucrose consumption occurs. Insulin has been shown to decrease sucrose intake by blocking the opioid response. Sucrose addiction has been described in rat model. With a concentrated sucrose solution to drink an opioid dependence developed with 1) increased consumption of sucrose 2) abstinence symptoms with no sucrose and 3) anxiety with an opiate blocker. Sucrose addiction in man has not been described in the scientific literature. There is an increased liking of sweets with alcoholic persons, which may be significant to support a strongly rewarding effect of sucrose, also in man. We should limit the access to sweet foods, in particular the sweet drinks. Insulin and insulin sensitivity may be an important factor to restrict the intake of sweet food.},
  author       = {Erlanson-Albertsson, Charlotte},
  issn         = {0023-7205},
  keyword      = {Insulin: administration & dosage,Insulin: physiology,Humans,Opioid: drug effects,Receptors,Opioid: physiology,Reward,Risk Factors,Substance Withdrawal Syndrome: psychology,Taste: drug effects,Taste: physiology,Animals,Appetite: drug effects,Appetite: physiology,Beverages: adverse effects,English Abstract,Food Habits,Dietary Sucrose: adverse effects,Dietary Sucrose: administration & dosage,Brain Mapping,Candy: adverse effects,Opioid Peptides: administration & dosage,Opioid Peptides: secretion,Rats},
  language     = {swe},
  number       = {21},
  pages        = {1620--1927},
  series       = {Läkartidningen},
  title        = {Socker triggar våra belöningssystem. Sött frisätter opiater som sätter fart på sötsuget - insulin kan dämpa det},
  volume       = {102},
  year         = {2005},
}