Socker triggar våra belöningssystem. Sött frisätter opiater som sätter fart på sötsuget - insulin kan dämpa det
(2005) In Läkartidningen 102(21). p.1620-1927- Abstract
- The consumption of sweet food has increased in Sweden, as in other Western countries. The type of food item has changed. The sweet is dominated by soft drinks. Appetite regulation for sucrose has been described in experimental animal models. It has been found that opioids stimulate appetite for sucrose. At the same time sucrose releases endogenous opioids so that a triggering of sucrose consumption occurs. Insulin has been shown to decrease sucrose intake by blocking the opioid response. Sucrose addiction has been described in rat model. With a concentrated sucrose solution to drink an opioid dependence developed with 1) increased consumption of sucrose 2) abstinence symptoms with no sucrose and 3) anxiety with an opiate blocker. Sucrose... (More)
- The consumption of sweet food has increased in Sweden, as in other Western countries. The type of food item has changed. The sweet is dominated by soft drinks. Appetite regulation for sucrose has been described in experimental animal models. It has been found that opioids stimulate appetite for sucrose. At the same time sucrose releases endogenous opioids so that a triggering of sucrose consumption occurs. Insulin has been shown to decrease sucrose intake by blocking the opioid response. Sucrose addiction has been described in rat model. With a concentrated sucrose solution to drink an opioid dependence developed with 1) increased consumption of sucrose 2) abstinence symptoms with no sucrose and 3) anxiety with an opiate blocker. Sucrose addiction in man has not been described in the scientific literature. There is an increased liking of sweets with alcoholic persons, which may be significant to support a strongly rewarding effect of sucrose, also in man. We should limit the access to sweet foods, in particular the sweet drinks. Insulin and insulin sensitivity may be an important factor to restrict the intake of sweet food. (Less)
- Abstract (Swedish)
- Intag av söta livsmedel har ökat i Sverige och övriga
västvärlden. Typ av söta livsmedel har också ändrat
karaktär; sött finns idag främst som dryck – läskkonsumtionen
står i särklass över andra söta drycker.
Aptitreglering för socker har beskrivits i djurmodeller,
där det visats att opiatfrisättning triggar sockerintag i
en uppåtgående spiral. Troligen gäller samma för
människa. Sött frisätter opiater och ger smärtlindring.
Sött, särskilt som dryck, stimulerar också aptiten. Insulin
minskar konsumtionen av sött genom att blockera
opiatfrisättning, enligt djurförsök.
Sockerberoende har beskrivits i djurmodell. Med sockerlösning
som... (More) - Intag av söta livsmedel har ökat i Sverige och övriga
västvärlden. Typ av söta livsmedel har också ändrat
karaktär; sött finns idag främst som dryck – läskkonsumtionen
står i särklass över andra söta drycker.
Aptitreglering för socker har beskrivits i djurmodeller,
där det visats att opiatfrisättning triggar sockerintag i
en uppåtgående spiral. Troligen gäller samma för
människa. Sött frisätter opiater och ger smärtlindring.
Sött, särskilt som dryck, stimulerar också aptiten. Insulin
minskar konsumtionen av sött genom att blockera
opiatfrisättning, enligt djurförsök.
Sockerberoende har beskrivits i djurmodell. Med sockerlösning
som dryck utvecklades beroende, dvs ökad
konsumtion av sött, abstinenssymtom då drycken
togs bort och ångest då opiatsystemet blockerades.
Sockerberoende hos människa är ännu inte redovisat
i vetenskapliga studier. Ökat sug efter sött hos nyktra
alkoholister stöder hypotesen att socker är kraftigt belönande,
även hos människa. Utveckling av sockerberoende
kräver troligen viss genetisk uppsättning av
belöningssystemet, som är nära kopplat till beroende.
Vi bör begränsa tillgången till sött, framför allt de
söta dryckerna. Insulin och insulinkänslighet kan
vara en viktig faktor för att hejda överintag av sött. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1134191
- author
- Erlanson-Albertsson, Charlotte LU
- organization
- alternative title
- Sugar triggers our reward-system. Sweets release opiates which stimulates the appetite for sucrose--insulin can depress it
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Insulin: administration & dosage, Insulin: physiology, Humans, Opioid: drug effects, Receptors, Opioid: physiology, Reward, Risk Factors, Substance Withdrawal Syndrome: psychology, Taste: drug effects, Taste: physiology, Animals, Appetite: drug effects, Appetite: physiology, Beverages: adverse effects, English Abstract, Food Habits, Dietary Sucrose: adverse effects, Dietary Sucrose: administration & dosage, Brain Mapping, Candy: adverse effects, Opioid Peptides: administration & dosage, Opioid Peptides: secretion, Rats
- in
- Läkartidningen
- volume
- 102
- issue
- 21
- pages
- 1620 - 1927
- publisher
- Swedish Medical Association
- external identifiers
-
- scopus:20444369530
- ISSN
- 0023-7205
- language
- Swedish
- LU publication?
- yes
- id
- b95a7dcf-7a49-4bfd-b356-c43ad99cba9b (old id 1134191)
- alternative location
- http://ltarkiv.lakartidningen.se/2005/temp/pda30239.pdf
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15962882&dopt=Abstract
- date added to LUP
- 2016-04-01 17:13:56
- date last changed
- 2022-01-29 01:17:11
@article{b95a7dcf-7a49-4bfd-b356-c43ad99cba9b,
abstract = {{The consumption of sweet food has increased in Sweden, as in other Western countries. The type of food item has changed. The sweet is dominated by soft drinks. Appetite regulation for sucrose has been described in experimental animal models. It has been found that opioids stimulate appetite for sucrose. At the same time sucrose releases endogenous opioids so that a triggering of sucrose consumption occurs. Insulin has been shown to decrease sucrose intake by blocking the opioid response. Sucrose addiction has been described in rat model. With a concentrated sucrose solution to drink an opioid dependence developed with 1) increased consumption of sucrose 2) abstinence symptoms with no sucrose and 3) anxiety with an opiate blocker. Sucrose addiction in man has not been described in the scientific literature. There is an increased liking of sweets with alcoholic persons, which may be significant to support a strongly rewarding effect of sucrose, also in man. We should limit the access to sweet foods, in particular the sweet drinks. Insulin and insulin sensitivity may be an important factor to restrict the intake of sweet food.}},
author = {{Erlanson-Albertsson, Charlotte}},
issn = {{0023-7205}},
keywords = {{Insulin: administration & dosage; Insulin: physiology; Humans; Opioid: drug effects; Receptors; Opioid: physiology; Reward; Risk Factors; Substance Withdrawal Syndrome: psychology; Taste: drug effects; Taste: physiology; Animals; Appetite: drug effects; Appetite: physiology; Beverages: adverse effects; English Abstract; Food Habits; Dietary Sucrose: adverse effects; Dietary Sucrose: administration & dosage; Brain Mapping; Candy: adverse effects; Opioid Peptides: administration & dosage; Opioid Peptides: secretion; Rats}},
language = {{swe}},
number = {{21}},
pages = {{1620--1927}},
publisher = {{Swedish Medical Association}},
series = {{Läkartidningen}},
title = {{Socker triggar våra belöningssystem. Sött frisätter opiater som sätter fart på sötsuget - insulin kan dämpa det}},
url = {{http://ltarkiv.lakartidningen.se/2005/temp/pda30239.pdf}},
volume = {{102}},
year = {{2005}},
}