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Risk factors and treatment at recurrent stroke onset: Results from the recurrent stroke quality and epidemiology (RESQUE) study

Leoo, T; Lindgren, Arne LU ; Petersson, Jesper LU and von Arbin, M (2008) In Cerebrovascular Diseases 25(3). p.254-260
Abstract
Background: Much effort has been made to study first-ever stroke patients. However, recurrent stroke has not been investigated as extensively. It is unclear which risk factors dominate, and whether adequate secondary prevention has been provided to patients who suffer from recurrent stroke. Also, the different types of recurrent stroke need further evaluation. Methods: The study included patients with recurrent stroke admitted to twenty-three Swedish stroke centers. The type of previous and recurrent stroke was determined, as well as evaluation ( when applicable) of recurrent ischemic stroke according to the TOAST classification. Presence of vascular risk factors was registered and compared to the type of stroke. Also assessed was ongoing... (More)
Background: Much effort has been made to study first-ever stroke patients. However, recurrent stroke has not been investigated as extensively. It is unclear which risk factors dominate, and whether adequate secondary prevention has been provided to patients who suffer from recurrent stroke. Also, the different types of recurrent stroke need further evaluation. Methods: The study included patients with recurrent stroke admitted to twenty-three Swedish stroke centers. The type of previous and recurrent stroke was determined, as well as evaluation ( when applicable) of recurrent ischemic stroke according to the TOAST classification. Presence of vascular risk factors was registered and compared to the type of stroke. Also assessed was ongoing secondary prevention treatment at recurrent stroke onset. Results: A total of 889 patients with recurrent stroke ( mean age 77) were included in the study. Of these, 805 (91%) had ischemic stroke, 78 (9%) had intracerebral hemorrhage and 6 (< 1%) stroke of unknown origin. The most frequent vascular risk factors were hypertension (75%) and hyperlipidemia (56%). Among the 889 patients, 29% had atrial fibrillation. Of the patients in the ischemic group with cardiac embolism, only 21% were on anticoagulation treatment. The majority of the patients (75%) had their most recent previous stroke > 12 months before admission. Conclusions: Few patients had a recurrent stroke shortly after the previous stroke in this study. This indicates that it is meaningful to prevent a second event with an adequate long-term treatment strategy for secondary prevention after first-ever stroke. There also seems to be a clear potential for improving secondary prevention after stroke. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
cardiovascular risk factors, ischemic stroke, recurrent stroke, intracerebral hemorrhage
in
Cerebrovascular Diseases
volume
25
issue
3
pages
254 - 260
publisher
Karger
external identifiers
  • wos:000253911800009
  • scopus:41349117377
ISSN
1421-9786
DOI
10.1159/000113864
language
English
LU publication?
yes
id
8ad1306a-78d7-486f-89f2-d1d5dedb5143 (old id 1186281)
date added to LUP
2008-09-03 14:19:43
date last changed
2017-11-19 03:32:48
@article{8ad1306a-78d7-486f-89f2-d1d5dedb5143,
  abstract     = {Background: Much effort has been made to study first-ever stroke patients. However, recurrent stroke has not been investigated as extensively. It is unclear which risk factors dominate, and whether adequate secondary prevention has been provided to patients who suffer from recurrent stroke. Also, the different types of recurrent stroke need further evaluation. Methods: The study included patients with recurrent stroke admitted to twenty-three Swedish stroke centers. The type of previous and recurrent stroke was determined, as well as evaluation ( when applicable) of recurrent ischemic stroke according to the TOAST classification. Presence of vascular risk factors was registered and compared to the type of stroke. Also assessed was ongoing secondary prevention treatment at recurrent stroke onset. Results: A total of 889 patients with recurrent stroke ( mean age 77) were included in the study. Of these, 805 (91%) had ischemic stroke, 78 (9%) had intracerebral hemorrhage and 6 (&lt; 1%) stroke of unknown origin. The most frequent vascular risk factors were hypertension (75%) and hyperlipidemia (56%). Among the 889 patients, 29% had atrial fibrillation. Of the patients in the ischemic group with cardiac embolism, only 21% were on anticoagulation treatment. The majority of the patients (75%) had their most recent previous stroke &gt; 12 months before admission. Conclusions: Few patients had a recurrent stroke shortly after the previous stroke in this study. This indicates that it is meaningful to prevent a second event with an adequate long-term treatment strategy for secondary prevention after first-ever stroke. There also seems to be a clear potential for improving secondary prevention after stroke.},
  author       = {Leoo, T and Lindgren, Arne and Petersson, Jesper and von Arbin, M},
  issn         = {1421-9786},
  keyword      = {cardiovascular risk factors,ischemic stroke,recurrent stroke,intracerebral hemorrhage},
  language     = {eng},
  number       = {3},
  pages        = {254--260},
  publisher    = {Karger},
  series       = {Cerebrovascular Diseases},
  title        = {Risk factors and treatment at recurrent stroke onset: Results from the recurrent stroke quality and epidemiology (RESQUE) study},
  url          = {http://dx.doi.org/10.1159/000113864},
  volume       = {25},
  year         = {2008},
}