Short-term outcome predictors in infants born at 23-24 gestational weeks
(2008) In Acta Pædiatrica 97(5). p.551-556- Abstract
- Aim: Outcome is uncertain in infants born at 23-24 gestational weeks. The aim of the present study was to identify possible early predictors of outcome in these infants. Materials and Methods: Data from the Swedish medical birth register (MBR) for live-born infants with gestational ages (GAs) 23 and 24 weeks, born during the time-period 2000-2002, were analysed in relation to short-term outcomes, that is survival and survival without severe brain damage (intraventricular haemorrhage [IVH] grades 3 and 4 and/or periventricular leukomalacia [PVL]). Results: In 57 infants born at 23 gestational weeks, survival was associated with birthweight (BW) (p = 0.018) and 5-min Apgar score (p = 0.020) on univariate analyses. In 99 infants born at 24... (More)
- Aim: Outcome is uncertain in infants born at 23-24 gestational weeks. The aim of the present study was to identify possible early predictors of outcome in these infants. Materials and Methods: Data from the Swedish medical birth register (MBR) for live-born infants with gestational ages (GAs) 23 and 24 weeks, born during the time-period 2000-2002, were analysed in relation to short-term outcomes, that is survival and survival without severe brain damage (intraventricular haemorrhage [IVH] grades 3 and 4 and/or periventricular leukomalacia [PVL]). Results: In 57 infants born at 23 gestational weeks, survival was associated with birthweight (BW) (p = 0.018) and 5-min Apgar score (p = 0.020) on univariate analyses. In 99 infants born at 24 weeks of gestation, survival without severe brain damage correlated with BW (p = 0.039), birth type (singleton/multiple) (p = 0.017) and Apgar score at 1, 5 and 10 min (p = 0.028, 0.014 and 0.030, respectively). The best model for predicting survival without severe brain damage in infants born at 24 gestational weeks was based on 5-min Apgar score and birth type. The small number of live-born infants at 23 weeks of gestation did not allow for multiple logistic regression analyses. Conclusion: The 5-min Apgar score is associated with short-term outcome in live-born infants at 23-24 gestational weeks. The association is stronger for infants born at 24 weeks of gestation. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1206550
- author
- Forsblad, Kristina LU ; Källén, Karin LU ; Marsal, Karel LU and Hellström-Westas, Lena LU
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- survival, prognosis, preterm, Apgar score, outcome
- in
- Acta Pædiatrica
- volume
- 97
- issue
- 5
- pages
- 551 - 556
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000254988600009
- scopus:41749125030
- pmid:18394098
- ISSN
- 1651-2227
- DOI
- 10.1111/j.1651-2227.2008.00737.x
- language
- English
- LU publication?
- yes
- id
- dd4f1eee-9b94-43d6-8154-5d93987c4ed8 (old id 1206550)
- date added to LUP
- 2016-04-01 14:45:16
- date last changed
- 2022-03-14 07:38:13
@article{dd4f1eee-9b94-43d6-8154-5d93987c4ed8, abstract = {{Aim: Outcome is uncertain in infants born at 23-24 gestational weeks. The aim of the present study was to identify possible early predictors of outcome in these infants. Materials and Methods: Data from the Swedish medical birth register (MBR) for live-born infants with gestational ages (GAs) 23 and 24 weeks, born during the time-period 2000-2002, were analysed in relation to short-term outcomes, that is survival and survival without severe brain damage (intraventricular haemorrhage [IVH] grades 3 and 4 and/or periventricular leukomalacia [PVL]). Results: In 57 infants born at 23 gestational weeks, survival was associated with birthweight (BW) (p = 0.018) and 5-min Apgar score (p = 0.020) on univariate analyses. In 99 infants born at 24 weeks of gestation, survival without severe brain damage correlated with BW (p = 0.039), birth type (singleton/multiple) (p = 0.017) and Apgar score at 1, 5 and 10 min (p = 0.028, 0.014 and 0.030, respectively). The best model for predicting survival without severe brain damage in infants born at 24 gestational weeks was based on 5-min Apgar score and birth type. The small number of live-born infants at 23 weeks of gestation did not allow for multiple logistic regression analyses. Conclusion: The 5-min Apgar score is associated with short-term outcome in live-born infants at 23-24 gestational weeks. The association is stronger for infants born at 24 weeks of gestation.}}, author = {{Forsblad, Kristina and Källén, Karin and Marsal, Karel and Hellström-Westas, Lena}}, issn = {{1651-2227}}, keywords = {{survival; prognosis; preterm; Apgar score; outcome}}, language = {{eng}}, number = {{5}}, pages = {{551--556}}, publisher = {{Wiley-Blackwell}}, series = {{Acta Pædiatrica}}, title = {{Short-term outcome predictors in infants born at 23-24 gestational weeks}}, url = {{http://dx.doi.org/10.1111/j.1651-2227.2008.00737.x}}, doi = {{10.1111/j.1651-2227.2008.00737.x}}, volume = {{97}}, year = {{2008}}, }