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Phase equilibria of model milk membrane lipid systems.

Waninge, Rianne LU ; Nylander, Tommy LU ; Paulsson, Marie LU and Bergenståhl, Björn LU (2003) In Chemistry and Physics of Lipids 125(1). p.59-68
Abstract
The phase behaviour of mixtures of recombined milk membrane lipids dioleoylphosphatidylcholine (DOPC), sphingomyelin (SM), dioleoylphosphatidylethanolamine (DOPE), phosphatidylinositol (PI) and dioleoylphosphatidylserine (DOPS) in 60% water was examined as a function of temperature between 5 and 90 °C. The aim was to examine under which lipid composition the average properties turn from balanced over to hydrophobic. The phase boundaries were determined by small angle X-ray diffraction (SAXD) and differential scanning calorimetry (DSC). The lamellar phase was dominating in the DOPC/SM/DOPE system. The phase boundary for the reversed hexagonal phase was only observed at high DOPE content within the examined temperature interval. The anionic... (More)
The phase behaviour of mixtures of recombined milk membrane lipids dioleoylphosphatidylcholine (DOPC), sphingomyelin (SM), dioleoylphosphatidylethanolamine (DOPE), phosphatidylinositol (PI) and dioleoylphosphatidylserine (DOPS) in 60% water was examined as a function of temperature between 5 and 90 °C. The aim was to examine under which lipid composition the average properties turn from balanced over to hydrophobic. The phase boundaries were determined by small angle X-ray diffraction (SAXD) and differential scanning calorimetry (DSC). The lamellar phase was dominating in the DOPC/SM/DOPE system. The phase boundary for the reversed hexagonal phase was only observed at high DOPE content within the examined temperature interval. The anionic phospholipids PI and DOPS induced a swollen lamellar phase, but no significant change of the transition between the lamellar phase and the reversed hexagonal phase was observed. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Small angle X-ray diffraction (SAXD), Differential scanning calorimetry (DSC), Phase behaviour, Milk fat globule membrane (MFGM), Phospholipid bilayer
in
Chemistry and Physics of Lipids
volume
125
issue
1
pages
59 - 68
publisher
Elsevier
external identifiers
  • pmid:14625076
  • wos:000185498500006
  • scopus:0242539733
ISSN
0009-3084
DOI
10.1016/S0009-3084(03)00070-7
language
English
LU publication?
yes
id
b0f75ee3-4809-49e1-9373-0efbcd5db78a (old id 129486)
date added to LUP
2007-07-12 14:01:15
date last changed
2018-01-14 04:02:22
@article{b0f75ee3-4809-49e1-9373-0efbcd5db78a,
  abstract     = {The phase behaviour of mixtures of recombined milk membrane lipids dioleoylphosphatidylcholine (DOPC), sphingomyelin (SM), dioleoylphosphatidylethanolamine (DOPE), phosphatidylinositol (PI) and dioleoylphosphatidylserine (DOPS) in 60% water was examined as a function of temperature between 5 and 90 °C. The aim was to examine under which lipid composition the average properties turn from balanced over to hydrophobic. The phase boundaries were determined by small angle X-ray diffraction (SAXD) and differential scanning calorimetry (DSC). The lamellar phase was dominating in the DOPC/SM/DOPE system. The phase boundary for the reversed hexagonal phase was only observed at high DOPE content within the examined temperature interval. The anionic phospholipids PI and DOPS induced a swollen lamellar phase, but no significant change of the transition between the lamellar phase and the reversed hexagonal phase was observed.},
  author       = {Waninge, Rianne and Nylander, Tommy and Paulsson, Marie and Bergenståhl, Björn},
  issn         = {0009-3084},
  keyword      = {Small angle X-ray diffraction (SAXD),Differential scanning calorimetry (DSC),Phase behaviour,Milk fat globule membrane (MFGM),Phospholipid bilayer},
  language     = {eng},
  number       = {1},
  pages        = {59--68},
  publisher    = {Elsevier},
  series       = {Chemistry and Physics of Lipids},
  title        = {Phase equilibria of model milk membrane lipid systems.},
  url          = {http://dx.doi.org/10.1016/S0009-3084(03)00070-7},
  volume       = {125},
  year         = {2003},
}