Phase equilibria of model milk membrane lipid systems.
(2003) In Chemistry and Physics of Lipids 125(1). p.59-68- Abstract
- The phase behaviour of mixtures of recombined milk membrane lipids dioleoylphosphatidylcholine (DOPC), sphingomyelin (SM), dioleoylphosphatidylethanolamine (DOPE), phosphatidylinositol (PI) and dioleoylphosphatidylserine (DOPS) in 60% water was examined as a function of temperature between 5 and 90 °C. The aim was to examine under which lipid composition the average properties turn from balanced over to hydrophobic. The phase boundaries were determined by small angle X-ray diffraction (SAXD) and differential scanning calorimetry (DSC). The lamellar phase was dominating in the DOPC/SM/DOPE system. The phase boundary for the reversed hexagonal phase was only observed at high DOPE content within the examined temperature interval. The anionic... (More)
- The phase behaviour of mixtures of recombined milk membrane lipids dioleoylphosphatidylcholine (DOPC), sphingomyelin (SM), dioleoylphosphatidylethanolamine (DOPE), phosphatidylinositol (PI) and dioleoylphosphatidylserine (DOPS) in 60% water was examined as a function of temperature between 5 and 90 °C. The aim was to examine under which lipid composition the average properties turn from balanced over to hydrophobic. The phase boundaries were determined by small angle X-ray diffraction (SAXD) and differential scanning calorimetry (DSC). The lamellar phase was dominating in the DOPC/SM/DOPE system. The phase boundary for the reversed hexagonal phase was only observed at high DOPE content within the examined temperature interval. The anionic phospholipids PI and DOPS induced a swollen lamellar phase, but no significant change of the transition between the lamellar phase and the reversed hexagonal phase was observed. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/129486
- author
- Waninge, Rianne LU ; Nylander, Tommy LU ; Paulsson, Marie LU and Bergenståhl, Björn LU
- organization
- publishing date
- 2003
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Small angle X-ray diffraction (SAXD), Differential scanning calorimetry (DSC), Phase behaviour, Milk fat globule membrane (MFGM), Phospholipid bilayer
- in
- Chemistry and Physics of Lipids
- volume
- 125
- issue
- 1
- pages
- 59 - 68
- publisher
- Elsevier
- external identifiers
-
- pmid:14625076
- wos:000185498500006
- scopus:0242539733
- ISSN
- 0009-3084
- DOI
- 10.1016/S0009-3084(03)00070-7
- language
- English
- LU publication?
- yes
- id
- b0f75ee3-4809-49e1-9373-0efbcd5db78a (old id 129486)
- date added to LUP
- 2016-04-01 16:15:09
- date last changed
- 2023-09-04 15:15:41
@article{b0f75ee3-4809-49e1-9373-0efbcd5db78a, abstract = {{The phase behaviour of mixtures of recombined milk membrane lipids dioleoylphosphatidylcholine (DOPC), sphingomyelin (SM), dioleoylphosphatidylethanolamine (DOPE), phosphatidylinositol (PI) and dioleoylphosphatidylserine (DOPS) in 60% water was examined as a function of temperature between 5 and 90 °C. The aim was to examine under which lipid composition the average properties turn from balanced over to hydrophobic. The phase boundaries were determined by small angle X-ray diffraction (SAXD) and differential scanning calorimetry (DSC). The lamellar phase was dominating in the DOPC/SM/DOPE system. The phase boundary for the reversed hexagonal phase was only observed at high DOPE content within the examined temperature interval. The anionic phospholipids PI and DOPS induced a swollen lamellar phase, but no significant change of the transition between the lamellar phase and the reversed hexagonal phase was observed.}}, author = {{Waninge, Rianne and Nylander, Tommy and Paulsson, Marie and Bergenståhl, Björn}}, issn = {{0009-3084}}, keywords = {{Small angle X-ray diffraction (SAXD); Differential scanning calorimetry (DSC); Phase behaviour; Milk fat globule membrane (MFGM); Phospholipid bilayer}}, language = {{eng}}, number = {{1}}, pages = {{59--68}}, publisher = {{Elsevier}}, series = {{Chemistry and Physics of Lipids}}, title = {{Phase equilibria of model milk membrane lipid systems.}}, url = {{http://dx.doi.org/10.1016/S0009-3084(03)00070-7}}, doi = {{10.1016/S0009-3084(03)00070-7}}, volume = {{125}}, year = {{2003}}, }