Advanced

Methodological Challenges In the Application of the Glycemic Index In Epidemiological Studies Using Data from the European Prospective Investigation into Cancer and Nutrition

van Bakel, Marit M. E.; Slimani, Nadia; Feskens, Edith J. M.; Du, Huaidong; Beulens, Joline W. J.; van der Schouw, Yvonne T.; Brighenti, Furio; Halkjaer, Jytte; Cust, Anne E. and Ferrari, Pietro, et al. (2009) In Journal of Nutrition 139(3). p.568-575
Abstract
Associations between the glycemic index (GI) or glycemic load (GL) and diseases are heterogeneous in epidemiological studies. Differences in assigning GI values to food items may contribute to this inconsistency. Our objective was to address methodological issues related to the use of current GI and GL values in epidemiological studies. We performed ecological comparison and correlation studies by calculating dietary GI and GL from country-specific dietary questionnaires (DO) from 422,837 participants from 9 countries participating in the European Prospective Investigation into Cancer and Nutrition study and single standardized 24-h dietary recalls (24-HDR) obtained from a representative sample (n = 33,404) using mainly Foster Powell's... (More)
Associations between the glycemic index (GI) or glycemic load (GL) and diseases are heterogeneous in epidemiological studies. Differences in assigning GI values to food items may contribute to this inconsistency. Our objective was to address methodological issues related to the use of current GI and GL values in epidemiological studies. We performed ecological comparison and correlation studies by calculating dietary GI and GL from country-specific dietary questionnaires (DO) from 422,837 participants from 9 countries participating in the European Prospective Investigation into Cancer and Nutrition study and single standardized 24-h dietary recalls (24-HDR) obtained from a representative sample (n = 33,404) using mainly Foster Powell's international table as a reference source. Further, 2 inter-rater and 1 inter-method comparison were conducted, comparing DO GI values assigned by independent groups with values linked by us. The ecological correlation between DO and 24-HDR was good for GL (overall r = 0.76; P < 0.005) and moderate for GI (r = 0.57; P < 0.05). Mean GI/GL differences between DQ and 24-HDR were significant for most centers. GL but not GI from DO was highly correlated with total carbohydrate (r = 0.98 and 0.15, respectively; P < 0.0001) and this was higher for starch (r = 0.72; P < 0.0001) than for sugars (r = 0.36; P < 0.0001). The inter-rater and inter-method variations were considerable for GI (weighted kappa coefficients of 0.49 and 0.65 for inter-rater and 0.25 for inter-method variation, respectively) but only mild for GL (weighted kappa Coefficients > 0.80). A more consistent methodology to attribute GI values to foods and validated DO is needed to derive meaningful GI/GL estimates for nutritional epidemiology. J. Nutr. 139: 568-575, 2009. (Less)
Please use this url to cite or link to this publication:
author
, et al. (More)
(Less)
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Nutrition
volume
139
issue
3
pages
568 - 575
publisher
American Society for Nutrition
external identifiers
  • wos:000263666600023
  • scopus:62749189916
ISSN
1541-6100
DOI
10.3945/jn.108.097121
language
English
LU publication?
yes
id
8e28801f-485d-4ef1-859c-1dc72aeb3b5c (old id 1371090)
date added to LUP
2009-05-08 15:25:13
date last changed
2017-04-16 03:30:02
@article{8e28801f-485d-4ef1-859c-1dc72aeb3b5c,
  abstract     = {Associations between the glycemic index (GI) or glycemic load (GL) and diseases are heterogeneous in epidemiological studies. Differences in assigning GI values to food items may contribute to this inconsistency. Our objective was to address methodological issues related to the use of current GI and GL values in epidemiological studies. We performed ecological comparison and correlation studies by calculating dietary GI and GL from country-specific dietary questionnaires (DO) from 422,837 participants from 9 countries participating in the European Prospective Investigation into Cancer and Nutrition study and single standardized 24-h dietary recalls (24-HDR) obtained from a representative sample (n = 33,404) using mainly Foster Powell's international table as a reference source. Further, 2 inter-rater and 1 inter-method comparison were conducted, comparing DO GI values assigned by independent groups with values linked by us. The ecological correlation between DO and 24-HDR was good for GL (overall r = 0.76; P &lt; 0.005) and moderate for GI (r = 0.57; P &lt; 0.05). Mean GI/GL differences between DQ and 24-HDR were significant for most centers. GL but not GI from DO was highly correlated with total carbohydrate (r = 0.98 and 0.15, respectively; P &lt; 0.0001) and this was higher for starch (r = 0.72; P &lt; 0.0001) than for sugars (r = 0.36; P &lt; 0.0001). The inter-rater and inter-method variations were considerable for GI (weighted kappa coefficients of 0.49 and 0.65 for inter-rater and 0.25 for inter-method variation, respectively) but only mild for GL (weighted kappa Coefficients &gt; 0.80). A more consistent methodology to attribute GI values to foods and validated DO is needed to derive meaningful GI/GL estimates for nutritional epidemiology. J. Nutr. 139: 568-575, 2009.},
  author       = {van Bakel, Marit M. E. and Slimani, Nadia and Feskens, Edith J. M. and Du, Huaidong and Beulens, Joline W. J. and van der Schouw, Yvonne T. and Brighenti, Furio and Halkjaer, Jytte and Cust, Anne E. and Ferrari, Pietro and Brand-Miller, Jennie and Bueno-de-Mesquita, H. Bas and Peeters, Petra and Ardanaz, Eva and Dorronsoro, Miren and Crowe, Francesca L. and Bingham, Sheila and Rohrmann, Sabine and Boeing, Heiner and Johansson, Ingegerd and Manjer, Jonas and Tjonneland, Anne and Overvad, Kim and Lund, Eiliv and Skeie, Guri and Mattiello, Amalia and Salvini, Simonetta and Clavel-Chapelon, Francoise and Kaakszs, Rudolf},
  issn         = {1541-6100},
  language     = {eng},
  number       = {3},
  pages        = {568--575},
  publisher    = {American Society for Nutrition},
  series       = {Journal of Nutrition},
  title        = {Methodological Challenges In the Application of the Glycemic Index In Epidemiological Studies Using Data from the European Prospective Investigation into Cancer and Nutrition},
  url          = {http://dx.doi.org/10.3945/jn.108.097121},
  volume       = {139},
  year         = {2009},
}