Advanced

SPECT findings in children with specific language impairment.

Ors, Marianne LU ; Ryding, Erik LU ; Lindgren, Magnus LU ; Gustafsson, Peik LU ; Blennow, Gösta LU and Rosén, Ingmar LU (2005) In Cortex 41(3). p.316-326
Abstract
Findings from 99mTc-HMPAO SPECT measurements at rest in a group of 19 school-age children with specific language

impairment (SLI) were compared to a group of 12 children with attention-deficit hyperactivity disorder (ADHD). The

regional cerebral blood flow (CBF) distributions were different in the two groups. Children with SLI showed significantly lower CBF values in the right parietal region and in the subcortical region compared to the ADHD group. In addition, the SLI group had symmetric CBF distributions in the left and right temporal regions, whereas the ADHD group showed the usual asymmetry with left-sided hemispheric predominance in the temporal regions. The findings give further evidence for anomalous... (More)
Findings from 99mTc-HMPAO SPECT measurements at rest in a group of 19 school-age children with specific language

impairment (SLI) were compared to a group of 12 children with attention-deficit hyperactivity disorder (ADHD). The

regional cerebral blood flow (CBF) distributions were different in the two groups. Children with SLI showed significantly lower CBF values in the right parietal region and in the subcortical region compared to the ADHD group. In addition, the SLI group had symmetric CBF distributions in the left and right temporal regions, whereas the ADHD group showed the usual asymmetry with left-sided hemispheric predominance in the temporal regions. The findings give further evidence for anomalous neurodevelopment with deviant hemispheric lateralization as an important factor in the aetiology of SLI. They also point to the role of subcortical structures in language impairment in childhood. Earlier focus on cortical structures in SLI research needs to be widened to include subcortical regions as well. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
lateralization, ADHD, specific language impairment, thalamus, language disorders, SPECT, basal ganglia
in
Cortex
volume
41
issue
3
pages
316 - 326
publisher
Elsevier
external identifiers
  • wos:000228941100005
  • pmid:15871597
  • scopus:17644363685
ISSN
1973-8102
language
English
LU publication?
yes
id
ef4c0a0d-c304-4200-8d52-66e76146919e (old id 138190)
alternative location
http://www.cortex-online.org/ftp/ftpDownloader.asp?action=downloadFile&dirID=158&fileID=812
date added to LUP
2007-06-25 14:38:33
date last changed
2017-01-01 07:37:07
@article{ef4c0a0d-c304-4200-8d52-66e76146919e,
  abstract     = {Findings from 99mTc-HMPAO SPECT measurements at rest in a group of 19 school-age children with specific language<br/><br>
impairment (SLI) were compared to a group of 12 children with attention-deficit hyperactivity disorder (ADHD). The<br/><br>
regional cerebral blood flow (CBF) distributions were different in the two groups. Children with SLI showed significantly lower CBF values in the right parietal region and in the subcortical region compared to the ADHD group. In addition, the SLI group had symmetric CBF distributions in the left and right temporal regions, whereas the ADHD group showed the usual asymmetry with left-sided hemispheric predominance in the temporal regions. The findings give further evidence for anomalous neurodevelopment with deviant hemispheric lateralization as an important factor in the aetiology of SLI. They also point to the role of subcortical structures in language impairment in childhood. Earlier focus on cortical structures in SLI research needs to be widened to include subcortical regions as well.},
  author       = {Ors, Marianne and Ryding, Erik and Lindgren, Magnus and Gustafsson, Peik and Blennow, Gösta and Rosén, Ingmar},
  issn         = {1973-8102},
  keyword      = {lateralization,ADHD,specific language impairment,thalamus,language disorders,SPECT,basal ganglia},
  language     = {eng},
  number       = {3},
  pages        = {316--326},
  publisher    = {Elsevier},
  series       = {Cortex},
  title        = {SPECT findings in children with specific language impairment.},
  volume       = {41},
  year         = {2005},
}