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Molecular exchange in thermal equilibrium between dissolved and crystalline tripalmitin by NMR

Löfborg, N; Smith, P; Furó, I and Bergenståhl, Björn LU (2003) In Journal of the American Oil Chemists Society 80(12). p.1187-1192
Abstract
An NMR technique to measure exchange kinetics at thermal equilibrium in dispersions of moderately soluble crystalline material is presented. By monitoring the exchange of molecules between pools in solid and dissolved form, one can characterize the surface specific exchange rate. Illustrative experiments were performed in a model system with beta-type crystals of tripalmitin as the solid phase and tripalmitin, a fraction of it deuterated, dissolved in a medium-chain TG oil as the liquid phase. The concentration of deuterated tripalmitin in the solvent was followed by H-2 NMR after the crystals, which initially lack deuterated tripalmitin, were immersed in the liquid. The variation of the H-2 concentration in the solvent provided the... (More)
An NMR technique to measure exchange kinetics at thermal equilibrium in dispersions of moderately soluble crystalline material is presented. By monitoring the exchange of molecules between pools in solid and dissolved form, one can characterize the surface specific exchange rate. Illustrative experiments were performed in a model system with beta-type crystals of tripalmitin as the solid phase and tripalmitin, a fraction of it deuterated, dissolved in a medium-chain TG oil as the liquid phase. The concentration of deuterated tripalmitin in the solvent was followed by H-2 NMR after the crystals, which initially lack deuterated tripalmitin, were immersed in the liquid. The variation of the H-2 concentration in the solvent provided the surface specific exchange rate. No systematic errors, due to the slight difference in properties of the deuterated tripalmitin compared to hydrogenated tripalmitin, were observed. The methodology worked well between crystal concentrations of 2 and 4 wt%. (Less)
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author
organization
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type
Contribution to journal
publication status
published
subject
in
Journal of the American Oil Chemists Society
volume
80
issue
12
pages
1187 - 1192
publisher
The American Oil Chemists' Society
external identifiers
  • wos:000187584400006
  • scopus:18244428623
ISSN
0003-021X
DOI
language
English
LU publication?
yes
id
f7750221-72a9-434a-9a85-43181509a7ff (old id 139363)
date added to LUP
2007-07-18 15:41:31
date last changed
2018-05-29 09:23:04
@article{f7750221-72a9-434a-9a85-43181509a7ff,
  abstract     = {An NMR technique to measure exchange kinetics at thermal equilibrium in dispersions of moderately soluble crystalline material is presented. By monitoring the exchange of molecules between pools in solid and dissolved form, one can characterize the surface specific exchange rate. Illustrative experiments were performed in a model system with beta-type crystals of tripalmitin as the solid phase and tripalmitin, a fraction of it deuterated, dissolved in a medium-chain TG oil as the liquid phase. The concentration of deuterated tripalmitin in the solvent was followed by H-2 NMR after the crystals, which initially lack deuterated tripalmitin, were immersed in the liquid. The variation of the H-2 concentration in the solvent provided the surface specific exchange rate. No systematic errors, due to the slight difference in properties of the deuterated tripalmitin compared to hydrogenated tripalmitin, were observed. The methodology worked well between crystal concentrations of 2 and 4 wt%.},
  author       = {Löfborg, N and Smith, P and Furó, I and Bergenståhl, Björn},
  issn         = {0003-021X},
  language     = {eng},
  number       = {12},
  pages        = {1187--1192},
  publisher    = {The American Oil Chemists' Society},
  series       = {Journal of the American Oil Chemists Society},
  title        = {Molecular exchange in thermal equilibrium between dissolved and crystalline tripalmitin by NMR},
  url          = {http://dx.doi.org/},
  volume       = {80},
  year         = {2003},
}