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Changes in serum lipids and postprandial glucose and insulin concentrations after consumption of beverages with beta-glucans from oats or barley: a randomised dose-controlled trial

Biörklund, Maria LU ; van Rees, A; Mensink, R P and Önning, Gunilla LU (2005) In European Journal of Clinical Nutrition 59(11). p.1272-1281
Abstract
Objectives: To investigate side by side the effects on serum lipoproteins and postprandial glucose and insulin concentrations of beverages enriched with 5 or 10 g of beta-glucans from oats or barley.



Design and setting: An 8-week single blind, controlled study with five parallel groups carried out at two centres under identical conditions.



Interventions: During a 3-week run-in period all subjects consumed a control beverage. For the following 5-week period four groups received a beverage with 5 or 10 g beta-glucans from oats or barley and one group continued with the control beverage. Blood samples in weeks 0, 2, 3, 7 and 8 were analysed for serum lipids, lipoproteins, glucose and insulin. Postprandial... (More)
Objectives: To investigate side by side the effects on serum lipoproteins and postprandial glucose and insulin concentrations of beverages enriched with 5 or 10 g of beta-glucans from oats or barley.



Design and setting: An 8-week single blind, controlled study with five parallel groups carried out at two centres under identical conditions.



Interventions: During a 3-week run-in period all subjects consumed a control beverage. For the following 5-week period four groups received a beverage with 5 or 10 g beta-glucans from oats or barley and one group continued with the control beverage. Blood samples in weeks 0, 2, 3, 7 and 8 were analysed for serum lipids, lipoproteins, glucose and insulin. Postprandial concentrations of glucose and insulin were compared between control and the beverage with 5 g of beta-glucans from oats or barley.



Results: Compared to control, 5 g of beta-glucans from oats significantly lowered total-cholesterol by 7.4% ( P<0.01), and postprandial concentrations of glucose ( 30 min, P = 0.005) and insulin ( 30 min, P = 0.025). The beverage with 10 g of beta-glucans from oats did not affect serum lipids significantly in comparison with control. No statistically significant effects compared to control of the beverages with barley beta-glucans were found.



Conclusions: A daily consumption of 5 g of oat beta-glucans in a beverage improved the lipid and glucose metabolism, while barley beta-glucans did not. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European Journal of Clinical Nutrition
volume
59
issue
11
pages
1272 - 1281
publisher
Nature Publishing Group
external identifiers
  • wos:000233019000007
  • pmid:16015250
  • scopus:27844510122
ISSN
1476-5640
DOI
10.1038/sj.ejcn.1602240
language
English
LU publication?
yes
id
64b7e55e-9690-4fd0-8d75-31b744ecd133 (old id 153227)
date added to LUP
2007-07-16 08:40:25
date last changed
2017-10-01 04:35:26
@article{64b7e55e-9690-4fd0-8d75-31b744ecd133,
  abstract     = {Objectives: To investigate side by side the effects on serum lipoproteins and postprandial glucose and insulin concentrations of beverages enriched with 5 or 10 g of beta-glucans from oats or barley.<br/><br>
<br/><br>
Design and setting: An 8-week single blind, controlled study with five parallel groups carried out at two centres under identical conditions.<br/><br>
<br/><br>
Interventions: During a 3-week run-in period all subjects consumed a control beverage. For the following 5-week period four groups received a beverage with 5 or 10 g beta-glucans from oats or barley and one group continued with the control beverage. Blood samples in weeks 0, 2, 3, 7 and 8 were analysed for serum lipids, lipoproteins, glucose and insulin. Postprandial concentrations of glucose and insulin were compared between control and the beverage with 5 g of beta-glucans from oats or barley.<br/><br>
<br/><br>
Results: Compared to control, 5 g of beta-glucans from oats significantly lowered total-cholesterol by 7.4% ( P&lt;0.01), and postprandial concentrations of glucose ( 30 min, P = 0.005) and insulin ( 30 min, P = 0.025). The beverage with 10 g of beta-glucans from oats did not affect serum lipids significantly in comparison with control. No statistically significant effects compared to control of the beverages with barley beta-glucans were found.<br/><br>
<br/><br>
Conclusions: A daily consumption of 5 g of oat beta-glucans in a beverage improved the lipid and glucose metabolism, while barley beta-glucans did not.},
  author       = {Biörklund, Maria and van Rees, A and Mensink, R P and Önning, Gunilla},
  issn         = {1476-5640},
  language     = {eng},
  number       = {11},
  pages        = {1272--1281},
  publisher    = {Nature Publishing Group},
  series       = {European Journal of Clinical Nutrition},
  title        = {Changes in serum lipids and postprandial glucose and insulin concentrations after consumption of beverages with beta-glucans from oats or barley: a randomised dose-controlled trial},
  url          = {http://dx.doi.org/10.1038/sj.ejcn.1602240},
  volume       = {59},
  year         = {2005},
}