Cerebral perfusion information obtained by dynamic contrast-enhanced phase-shift magnetic resonance imaging: comparison with model-free arterial spin labelling.
Wirestam, Ronnie LU
; Lindgren, Emelie
LU
; van Westen, Danielle
LU
; Markenroth Bloch, Karin
LU
; Ståhlberg, Freddy
LU
and Knutsson, Linda
LU
(2010)
In Clinical Physiology and Functional Imaging
30(5).
p.375-379
- Abstract
- Summary Phase-shift time curves following a bolus injection of gadolinium contrast agent were registered for grey-matter regions and large vessels in 14 subjects. Deconvolving a tissue phase-shift curve with a phase-based arterial input function resulted in a tissue residue function R(t). The peak value of R(t) provided a relative cerebral blood flow (CBF) index, while the area-to-height ratio of R(t) provided quantitative mean transit time (MTT). For comparison, quantitative CBF values in grey matter were acquired using model-free arterial spin labelling (ASL). The phase-based relative CBF estimates showed good linear correlation with ASL-based CBF (r = 0.82). Grey-matter MTT was 4.9 +/- 1.1 s (mean +/- SD).
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1645132
- author
- Wirestam, Ronnie
LU
; Lindgren, Emelie
LU
; van Westen, Danielle
LU
; Markenroth Bloch, Karin
LU
; Ståhlberg, Freddy
LU
and Knutsson, Linda
LU
- organization
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Clinical Physiology and Functional Imaging
- volume
- 30
- issue
- 5
- pages
- 375 - 379
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000280630600012
- pmid:20618360
- scopus:77955815940
- pmid:20618360
- ISSN
- 1475-0961
- DOI
- 10.1111/j.1475-097X.2010.00947.x
- project
- MRI brain perfusion quantification at 3 tesla using arterial spin labeling
- Optimisation and Validation of Dynamic Susceptibility Contrast MRI
- language
- English
- LU publication?
- yes
- id
- e501f7ca-9693-4bcb-9763-507309e3ed75 (old id 1645132)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/20618360?dopt=Abstract
- date added to LUP
- 2016-04-01 09:49:15
- date last changed
- 2022-03-07 14:21:03
@article{e501f7ca-9693-4bcb-9763-507309e3ed75,
abstract = {{Summary Phase-shift time curves following a bolus injection of gadolinium contrast agent were registered for grey-matter regions and large vessels in 14 subjects. Deconvolving a tissue phase-shift curve with a phase-based arterial input function resulted in a tissue residue function R(t). The peak value of R(t) provided a relative cerebral blood flow (CBF) index, while the area-to-height ratio of R(t) provided quantitative mean transit time (MTT). For comparison, quantitative CBF values in grey matter were acquired using model-free arterial spin labelling (ASL). The phase-based relative CBF estimates showed good linear correlation with ASL-based CBF (r = 0.82). Grey-matter MTT was 4.9 +/- 1.1 s (mean +/- SD).}},
author = {{Wirestam, Ronnie and Lindgren, Emelie and van Westen, Danielle and Markenroth Bloch, Karin and Ståhlberg, Freddy and Knutsson, Linda}},
issn = {{1475-0961}},
language = {{eng}},
number = {{5}},
pages = {{375--379}},
publisher = {{John Wiley & Sons Inc.}},
series = {{Clinical Physiology and Functional Imaging}},
title = {{Cerebral perfusion information obtained by dynamic contrast-enhanced phase-shift magnetic resonance imaging: comparison with model-free arterial spin labelling.}},
url = {{http://dx.doi.org/10.1111/j.1475-097X.2010.00947.x}},
doi = {{10.1111/j.1475-097X.2010.00947.x}},
volume = {{30}},
year = {{2010}},
}