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Impact of exercise intensity and duration on insulin sensitivity in women with T2D.

Tornberg, Åsa LU ; Glans, Forouzan LU ; Eriksson, Karl-Fredrik LU ; Drake, Anna Maria LU ; Groop, Leif LU ; Thorsson, Ola LU and Wollmer, Per LU (2010) In European Journal of Internal Medicine 21(5). p.404-408
Abstract
BACKGROUND: Clinical guidelines seldom provide in depth information about the most suitable type and intensity of exercise to obtain optimal benefit in different subgroups of T2D individuals. The aim of this study was to examine the effect of group exercise training on exercise capacity, insulin sensitivity and HbA1c in women with diabetes. METHODS: Twenty-two women with T2D participated in a supervised group exercise program for six months. The program combined endurance and resistance exercise. The duration and intensity of exercise for each subject was recorded. The volume of exercise was calculated as the product of exercise duration and intensity. Exercise capacity, insulin sensitivity and HbA1c were measured at baseline and after six... (More)
BACKGROUND: Clinical guidelines seldom provide in depth information about the most suitable type and intensity of exercise to obtain optimal benefit in different subgroups of T2D individuals. The aim of this study was to examine the effect of group exercise training on exercise capacity, insulin sensitivity and HbA1c in women with diabetes. METHODS: Twenty-two women with T2D participated in a supervised group exercise program for six months. The program combined endurance and resistance exercise. The duration and intensity of exercise for each subject was recorded. The volume of exercise was calculated as the product of exercise duration and intensity. Exercise capacity, insulin sensitivity and HbA1c were measured at baseline and after six months of training. The subjects were dichotomized with respect to training volume in a high training volume group and a low training volume group. RESULTS: Exercise capacity did not change significantly during the training period. Insulin sensitivity increased significantly and HbA1c decreased significantly from baseline in the high volume group but not in the low volume group. The increase in insulin sensitivity was explained with the intensity of exercise by 30%. The reduction in HbA1c was explained with exercise by 25%. CONCLUSION: Improvement in insulin sensitivity after six months combined supervised group training in female diabetic subjects is related to exercise intensity, whereas the reduction in HbA1c is related mainly to training volume. Metabolic effects of training may be seen in the absence of improved exercise capacity. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European Journal of Internal Medicine
volume
21
issue
5
pages
404 - 408
publisher
Elsevier
external identifiers
  • wos:000281603900012
  • pmid:20816594
  • scopus:77956414755
ISSN
1879-0828
DOI
10.1016/j.ejim.2010.05.003
language
English
LU publication?
yes
id
50b00b1d-c919-46f4-bd3d-ff6eed8ed31d (old id 1688551)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/20816594?dopt=Abstract
date added to LUP
2010-10-05 08:37:28
date last changed
2018-05-29 09:22:35
@article{50b00b1d-c919-46f4-bd3d-ff6eed8ed31d,
  abstract     = {BACKGROUND: Clinical guidelines seldom provide in depth information about the most suitable type and intensity of exercise to obtain optimal benefit in different subgroups of T2D individuals. The aim of this study was to examine the effect of group exercise training on exercise capacity, insulin sensitivity and HbA1c in women with diabetes. METHODS: Twenty-two women with T2D participated in a supervised group exercise program for six months. The program combined endurance and resistance exercise. The duration and intensity of exercise for each subject was recorded. The volume of exercise was calculated as the product of exercise duration and intensity. Exercise capacity, insulin sensitivity and HbA1c were measured at baseline and after six months of training. The subjects were dichotomized with respect to training volume in a high training volume group and a low training volume group. RESULTS: Exercise capacity did not change significantly during the training period. Insulin sensitivity increased significantly and HbA1c decreased significantly from baseline in the high volume group but not in the low volume group. The increase in insulin sensitivity was explained with the intensity of exercise by 30%. The reduction in HbA1c was explained with exercise by 25%. CONCLUSION: Improvement in insulin sensitivity after six months combined supervised group training in female diabetic subjects is related to exercise intensity, whereas the reduction in HbA1c is related mainly to training volume. Metabolic effects of training may be seen in the absence of improved exercise capacity.},
  author       = {Tornberg, Åsa and Glans, Forouzan and Eriksson, Karl-Fredrik and Drake, Anna Maria and Groop, Leif and Thorsson, Ola and Wollmer, Per},
  issn         = {1879-0828},
  language     = {eng},
  number       = {5},
  pages        = {404--408},
  publisher    = {Elsevier},
  series       = {European Journal of Internal Medicine},
  title        = {Impact of exercise intensity and duration on insulin sensitivity in women with T2D.},
  url          = {http://dx.doi.org/10.1016/j.ejim.2010.05.003},
  volume       = {21},
  year         = {2010},
}