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Candida albicans- a pre-whole genome duplication yeast is predominantly aerobic and a poor ethanol producer.

Rozpedowska, Elzbieta LU ; Galafassi, Silvia LU ; Johansson, Louise LU ; Hagman, Arne LU ; Piskur, Jure LU and Compagno, Concetta (2011) In FEMS Yeast Research 11(3). p.285-291
Abstract
Yeast species belonging to the lineage that underwent the whole genome duplication (WGD), and including Saccharomyces cerevisiae, can grow under anaerobiosis and accumulate ethanol in the presence of glucose and oxygen. The pre-WGD yeasts, which branched from the S. cerevisiae lineage just prior to the WGD event, including Kluyveromyces lactis, are more dependent on oxygen and do not accumulate large amounts of ethanol in the presence of excess oxygen. Yeasts that belong to the so-called 'lower branches' of the yeast phylogenetic tree and diverged from S. cerevisiae more than 200 million years ago, have so far not been thoroughly investigated for their physiology and carbon metabolism. We have hereby studied several isolates of Candida... (More)
Yeast species belonging to the lineage that underwent the whole genome duplication (WGD), and including Saccharomyces cerevisiae, can grow under anaerobiosis and accumulate ethanol in the presence of glucose and oxygen. The pre-WGD yeasts, which branched from the S. cerevisiae lineage just prior to the WGD event, including Kluyveromyces lactis, are more dependent on oxygen and do not accumulate large amounts of ethanol in the presence of excess oxygen. Yeasts that belong to the so-called 'lower branches' of the yeast phylogenetic tree and diverged from S. cerevisiae more than 200 million years ago, have so far not been thoroughly investigated for their physiology and carbon metabolism. We have hereby studied several isolates of Candida albicans and Debaryomyces hansenii for their dependence on oxygen. C. albicans grew very poorly at oxygen concentration below 1 p.p.m. and D. hansenii could not grow at all. In aerobic batch cultivations C. albicans exhibited a predominately aerobic metabolism, accumulating only small amounts of ethanol (0.01-0.09 g g(-1) glucose). Apparently, C. albicans and several other pre-WGD yeasts still exhibit the original traits of the yeast progenitor: poor accumulation of ethanol under aerobic conditions and strong dependence on the presence of oxygen. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
molecular evolution, yeast progenitor, respiration, fermentation, obligate aerobes
in
FEMS Yeast Research
volume
11
issue
3
pages
285 - 291
publisher
Elsevier
external identifiers
  • wos:000289364400005
  • scopus:79953901945
ISSN
1567-1364
DOI
10.1111/j.1567-1364.2010.00715.x
language
English
LU publication?
yes
id
c8b6e5fe-f091-45b3-b7d6-344c0364a347 (old id 1777798)
date added to LUP
2011-02-07 12:45:19
date last changed
2017-01-01 04:06:49
@article{c8b6e5fe-f091-45b3-b7d6-344c0364a347,
  abstract     = {Yeast species belonging to the lineage that underwent the whole genome duplication (WGD), and including Saccharomyces cerevisiae, can grow under anaerobiosis and accumulate ethanol in the presence of glucose and oxygen. The pre-WGD yeasts, which branched from the S. cerevisiae lineage just prior to the WGD event, including Kluyveromyces lactis, are more dependent on oxygen and do not accumulate large amounts of ethanol in the presence of excess oxygen. Yeasts that belong to the so-called 'lower branches' of the yeast phylogenetic tree and diverged from S. cerevisiae more than 200 million years ago, have so far not been thoroughly investigated for their physiology and carbon metabolism. We have hereby studied several isolates of Candida albicans and Debaryomyces hansenii for their dependence on oxygen. C. albicans grew very poorly at oxygen concentration below 1 p.p.m. and D. hansenii could not grow at all. In aerobic batch cultivations C. albicans exhibited a predominately aerobic metabolism, accumulating only small amounts of ethanol (0.01-0.09 g g(-1) glucose). Apparently, C. albicans and several other pre-WGD yeasts still exhibit the original traits of the yeast progenitor: poor accumulation of ethanol under aerobic conditions and strong dependence on the presence of oxygen.},
  author       = {Rozpedowska, Elzbieta and Galafassi, Silvia and Johansson, Louise and Hagman, Arne and Piskur, Jure and Compagno, Concetta},
  issn         = {1567-1364},
  keyword      = {molecular evolution,yeast progenitor,respiration,fermentation,obligate aerobes},
  language     = {eng},
  number       = {3},
  pages        = {285--291},
  publisher    = {Elsevier},
  series       = {FEMS Yeast Research},
  title        = {Candida albicans- a pre-whole genome duplication yeast is predominantly aerobic and a poor ethanol producer.},
  url          = {http://dx.doi.org/10.1111/j.1567-1364.2010.00715.x},
  volume       = {11},
  year         = {2011},
}