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Inhibition of ConA-induced proliferative response in human lymphocytes by podophyllotoxin and a detergent, Tween80

Månsson, Bengt LU orcid ; Geborek, Pierre LU ; Hallberg, T and Sturfelt, Gunnar LU (1988) In Clinical and Experimental Rheumatology 6(4). p.405-407
Abstract
Podophyllotoxin (CPH86), at concentrations of 5 ng/ml or more, inhibited [3H]-thymidine uptake of ConA-induced proliferation of human peripheral mononuclear blood cells. Tween80, the detergent included in the anti-inflammatory drug Proresid, containing podophyllum lignan derivatives, also inhibited lymphocyte proliferation in a dose-dependent manner. Combination of the two drugs did not, or did only weakly, potentiate the inhibitory effect of each drug.
Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Clinical and Experimental Rheumatology
volume
6
issue
4
pages
405 - 407
publisher
Pacini
external identifiers
  • pmid:3229031
ISSN
1593-098X
language
English
LU publication?
yes
id
1e9713ca-a79d-4e09-bd4f-dc1734300b14 (old id 1104258)
date added to LUP
2016-04-01 12:21:44
date last changed
2018-11-21 20:06:39
@article{1e9713ca-a79d-4e09-bd4f-dc1734300b14,
  abstract     = {{Podophyllotoxin (CPH86), at concentrations of 5 ng/ml or more, inhibited [3H]-thymidine uptake of ConA-induced proliferation of human peripheral mononuclear blood cells. Tween80, the detergent included in the anti-inflammatory drug Proresid, containing podophyllum lignan derivatives, also inhibited lymphocyte proliferation in a dose-dependent manner. Combination of the two drugs did not, or did only weakly, potentiate the inhibitory effect of each drug.}},
  author       = {{Månsson, Bengt and Geborek, Pierre and Hallberg, T and Sturfelt, Gunnar}},
  issn         = {{1593-098X}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{405--407}},
  publisher    = {{Pacini}},
  series       = {{Clinical and Experimental Rheumatology}},
  title        = {{Inhibition of ConA-induced proliferative response in human lymphocytes by podophyllotoxin and a detergent, Tween80}},
  volume       = {{6}},
  year         = {{1988}},
}