Reperfusion of Free Full-Thickness Skin Grafts in Periocular Reconstructive Surgery Monitored Using Laser Speckle Contrast Imaging
(2021) In Ophthalmic Plastic and Reconstructive Surgery 37(4). p.324-328- Abstract
PURPOSE: Free skin grafts are frequently used in reconstructive surgery. However, little is known about the course of reperfusion due to the previous lack of reliable perfusion monitoring techniques. The aim of this study was to use state-of-the-art laser speckle contrast imaging to monitor free skin grafts in the periocular area.
METHODS: Seven patients needing surgery due to tumor removal or cicatricial ectropion in the periocular region underwent reconstructive surgery using free skin grafts from either the contralateral upper eyelid or the upper inner arm. The free skin grafts measured 10-30 mm horizontally and 9-30 mm vertically. Blood perfusion was monitored using laser speckle contrast imaging immediately postoperatively (0... (More)
PURPOSE: Free skin grafts are frequently used in reconstructive surgery. However, little is known about the course of reperfusion due to the previous lack of reliable perfusion monitoring techniques. The aim of this study was to use state-of-the-art laser speckle contrast imaging to monitor free skin grafts in the periocular area.
METHODS: Seven patients needing surgery due to tumor removal or cicatricial ectropion in the periocular region underwent reconstructive surgery using free skin grafts from either the contralateral upper eyelid or the upper inner arm. The free skin grafts measured 10-30 mm horizontally and 9-30 mm vertically. Blood perfusion was monitored using laser speckle contrast imaging immediately postoperatively (0 weeks) and at follow-up after 1, 3, and 7 weeks.
RESULTS: All grafts were reperfused gradually during healing, the median value being 46% in the central part of the graft after 1 week and 79% after 3 weeks. The grafts were completely reperfused after 7 weeks. No difference was observed in the rate of reperfusion between the center and periphery of the grafts (p = not significant). The cosmetic and functional outcome was excellent in all but 1 patient, who developed ectropion that had to be surgically corrected.
CONCLUSIONS: Skin grafts in the periorbital area are fully reperfused after 7 weeks. The periocular area is known to be well-vascularized and thus forgiving to reconstructive surgery. Future investigations of the reperfusion of free skin grafts in other parts of the body or in higher-risk populations should be carried out.
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- author
- Berggren, Johanna LU ; Castelo, Nazia LU ; Tenland, Kajsa LU ; Dahlstrand, Ulf LU ; Engelsberg, Karl LU ; Lindstedt, Sandra LU ; Sheikh, Rafi LU and Malmsjö, Malin LU
- organization
-
- Ophthalmology Imaging Research Group (research group)
- Ophthalmology, Lund
- Clinical Sciences, Helsingborg
- Clinical and experimental lung transplantation (research group)
- LUCC: Lund University Cancer Centre
- WCMM-Wallenberg Centre for Molecular Medicine
- StemTherapy: National Initiative on Stem Cells for Regenerative Therapy
- Lung Bioengineering and Regeneration (research group)
- NPWT technology (research group)
- DCD transplantation of lungs (research group)
- Thoracic Surgery
- publishing date
- 2021
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Ophthalmic Plastic and Reconstructive Surgery
- volume
- 37
- issue
- 4
- pages
- 324 - 328
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- pmid:32991497
- scopus:85110185282
- ISSN
- 1537-2677
- DOI
- 10.1097/IOP.0000000000001851
- language
- English
- LU publication?
- yes
- id
- 2202cca1-e31f-41b4-aad8-439e6f3af690
- date added to LUP
- 2020-12-30 11:39:18
- date last changed
- 2024-09-05 11:12:08
@article{2202cca1-e31f-41b4-aad8-439e6f3af690, abstract = {{<p>PURPOSE: Free skin grafts are frequently used in reconstructive surgery. However, little is known about the course of reperfusion due to the previous lack of reliable perfusion monitoring techniques. The aim of this study was to use state-of-the-art laser speckle contrast imaging to monitor free skin grafts in the periocular area.</p><p>METHODS: Seven patients needing surgery due to tumor removal or cicatricial ectropion in the periocular region underwent reconstructive surgery using free skin grafts from either the contralateral upper eyelid or the upper inner arm. The free skin grafts measured 10-30 mm horizontally and 9-30 mm vertically. Blood perfusion was monitored using laser speckle contrast imaging immediately postoperatively (0 weeks) and at follow-up after 1, 3, and 7 weeks.</p><p>RESULTS: All grafts were reperfused gradually during healing, the median value being 46% in the central part of the graft after 1 week and 79% after 3 weeks. The grafts were completely reperfused after 7 weeks. No difference was observed in the rate of reperfusion between the center and periphery of the grafts (p = not significant). The cosmetic and functional outcome was excellent in all but 1 patient, who developed ectropion that had to be surgically corrected.</p><p>CONCLUSIONS: Skin grafts in the periorbital area are fully reperfused after 7 weeks. The periocular area is known to be well-vascularized and thus forgiving to reconstructive surgery. Future investigations of the reperfusion of free skin grafts in other parts of the body or in higher-risk populations should be carried out.</p>}}, author = {{Berggren, Johanna and Castelo, Nazia and Tenland, Kajsa and Dahlstrand, Ulf and Engelsberg, Karl and Lindstedt, Sandra and Sheikh, Rafi and Malmsjö, Malin}}, issn = {{1537-2677}}, language = {{eng}}, number = {{4}}, pages = {{324--328}}, publisher = {{Lippincott Williams & Wilkins}}, series = {{Ophthalmic Plastic and Reconstructive Surgery}}, title = {{Reperfusion of Free Full-Thickness Skin Grafts in Periocular Reconstructive Surgery Monitored Using Laser Speckle Contrast Imaging}}, url = {{http://dx.doi.org/10.1097/IOP.0000000000001851}}, doi = {{10.1097/IOP.0000000000001851}}, volume = {{37}}, year = {{2021}}, }