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Gut Microbiota and Inflammation

Håkansson, Åsa LU and Molin, Göran LU (2011) In Nutrients 3(6). p.637-682
Abstract
Systemic and local inflammation in relation to the resident microbiota of the human gastro-intestinal (GI) tract and administration of probiotics are the main themes of the present review. The dominating taxa of the human GI tract and their potential for aggravating or suppressing inflammation are described. The review focuses on human trials with probiotics and does not include in vitro studies and animal experimental models. The applications of probiotics considered are systemic immune-modulation, the metabolic syndrome, liver injury, inflammatory bowel disease, colorectal cancer and radiation-induced enteritis. When the major genomic differences between different types of probiotics are taken into account, it is to be expected that the... (More)
Systemic and local inflammation in relation to the resident microbiota of the human gastro-intestinal (GI) tract and administration of probiotics are the main themes of the present review. The dominating taxa of the human GI tract and their potential for aggravating or suppressing inflammation are described. The review focuses on human trials with probiotics and does not include in vitro studies and animal experimental models. The applications of probiotics considered are systemic immune-modulation, the metabolic syndrome, liver injury, inflammatory bowel disease, colorectal cancer and radiation-induced enteritis. When the major genomic differences between different types of probiotics are taken into account, it is to be expected that the human body can respond differently to the different species and strains of probiotics. This fact is often neglected in discussions of the outcome of clinical trials with probiotics. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
probiotics, inflammation, gut microbiota
in
Nutrients
volume
3
issue
6
pages
637 - 682
publisher
MDPI AG
external identifiers
  • wos:000298246000001
  • scopus:79959861780
ISSN
2072-6643
DOI
10.3390/nu3060637
language
English
LU publication?
yes
id
b2a91710-fa20-40ff-aa3d-a9f7aae439ce (old id 2333559)
date added to LUP
2012-01-31 08:34:24
date last changed
2017-11-05 04:01:49
@article{b2a91710-fa20-40ff-aa3d-a9f7aae439ce,
  abstract     = {Systemic and local inflammation in relation to the resident microbiota of the human gastro-intestinal (GI) tract and administration of probiotics are the main themes of the present review. The dominating taxa of the human GI tract and their potential for aggravating or suppressing inflammation are described. The review focuses on human trials with probiotics and does not include in vitro studies and animal experimental models. The applications of probiotics considered are systemic immune-modulation, the metabolic syndrome, liver injury, inflammatory bowel disease, colorectal cancer and radiation-induced enteritis. When the major genomic differences between different types of probiotics are taken into account, it is to be expected that the human body can respond differently to the different species and strains of probiotics. This fact is often neglected in discussions of the outcome of clinical trials with probiotics.},
  author       = {Håkansson, Åsa and Molin, Göran},
  issn         = {2072-6643},
  keyword      = {probiotics,inflammation,gut microbiota},
  language     = {eng},
  number       = {6},
  pages        = {637--682},
  publisher    = {MDPI AG},
  series       = {Nutrients},
  title        = {Gut Microbiota and Inflammation},
  url          = {http://dx.doi.org/10.3390/nu3060637},
  volume       = {3},
  year         = {2011},
}